Cilnidipine CAS 132203-70-4
132203-70-4
Pharmaceutical Grade
99%
SHANGHAI
airuike
25kg/Cardboard Drum
2025-07-20
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceYellow Crystalline SolidChEBI: A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.Clinidipine is a kind of calcium channel blocker. It is a kind of novel calcium antagonist with the blocking effect on both L-type and N-type calcium channels. It is mainly used for the treatment of hypertension. Based on its effect on both N-type and L-type calcium channel, it can dilate both arterioles and venules, further reducing the pressure
Cilnidipine is a diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive. It has a role as a calcium channel blocker, an antihypertensive agent and a cardiovascular drug. It is a dihydropyridine, a 2-methoxyethyl ester and a C-nitro compound.|Cilnidipine is a dihydropyridine calcium antagonist. It was jointly developed by Fuji Viscera Pharmaceutical Company, Japan and Ajinomoto, Japan and approved in 1995. Compared with other calcium antagonists, cilnidipine can act on the N-type calcium channel that existing sympathetic nerve end besides acting on L-type calcium channel that similar to most of the calcium antagonists. This drug is approved in China, Japan, Korea, India, and several countries in the European Union.Basic Info-
Product Name:
Cilnidipine
Other Name:3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-(2-methoxyethyl) 5-[(2E)-3-phenyl-2-propen-1-yl] ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl 3-phenyl-2-propenyl ester,(E)-(±)-;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl (2E)-3-phenyl-2-propenyl ester;(±)-FRC 8653;FRC 8653;Cilnidipine;Atelec;Cinalong;Siscard;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl 3-phenyl-2-propenyl ester,(E)-;FRG 8653;Cinaldipine;Cilacar 10;153220-67-8
CAS No.:132203-70-4
Molecular Formula:C27H28N2O7
InChIKeys:InChIKey=KJEBULYHNRNJTE-DHZHZOJONA-N
Molecular Weight:492.52
Exact Mass:492.52
EC Number:1806241-263-5
UNII:S85436ZG85|4LNU2SU262
DSSTox ID:DTXSID0046309
ATC Code:C - Cardiovascular system
HScode:29333990
Categories:
Characteristics-
PSA:
120
XLogP3:4.4
Appearance:light yellow
Density:1.240±0.06 g/cm3(Predicted)
Melting Point:115.5-116.6 °C
Boiling Point:653ºC
Flash Point:348.5±31.5 °C
Refractive Index:1.592
Water Solubility:H2O: Insoluble
Storage Conditions:Store at +4°C
Vapor Pressure:0mmHg at 25°C
Toxicity:LD50 in male, female mice, rats (mg/kg): 5000, 5000, 5000, 4412 orally; 5000 all species s.c.; 1845, 2353, 441, 426 i.p. (Wada)
PKA:11.39None
Dissociation Constants:11.39
Hazard IdentificationClassification of the substance or mixture
Serious eye damage, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H318 Causes serious eye damage
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
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Certifications:
Credit rating certificate,Hazardous Chemicals Business License
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
