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Votioxtine hydrobromide CAS 960203-27-4 supply high quality fast delivery best service

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CAS No.:

960203-27-4

Grade:

Pharmaceutical Grade

Content:

99.36%

Brand:

Million

Packaging:

25kg/Cardboard Drum

Price valid (until):

2024-10-19

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Jinan Million Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

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Product Description
Seller Information
Inquiry History

Description

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 1

-Product Descrition-

General: Votixetin hydrobromide is considered to be a new multi-model antidepressant drug. In vitro studies have shown that it can antagonize 5-HT3, 5-HT7 and 5-HT1D receptors, activate 5-HT1A receptors, and partially activate 5-HT1A receptors. HT1B receptor and inhibition of 5-HT transport. It is a slightly yellowish white powder that is slightly soluble in water. Votexeting is an antidepressant with multiple mechanisms of action, acting not only on 5-HT transporters but also on a variety of 5-HT receptors. This drug has high affinity to 5-HT transporters, which can bind various 5-HT receptors and can exert multiple pharmacological effects by binding to the corresponding transporters and receptors.

Product introduce：Vrtioxetin hydrobromide is a drug used for the treatment of depression and anxiety. Vrtexetine hydrobromide is considered as a new multi-model antidepressant. In vitro studies show that it can antagonize 5-HT3, 5-HT7 and 5-HT1D receptors, activate 5-HT1A receptors, partially activate 5-HT1B receptors and inhibit 5-HT transport.

Function : It is an antidepressant. It is used to treat anxiety and depression. Votisidine hydrobromide is a yellowish white powder, which is slightly soluble in water.

Origi n ：Votioxetne hydrobromide is a new diaryl thioalkylamine antidepressant jointly developed by Takeda, Japan and Lingbei, Denmark, which is used for the treatment of depression and anxiety.In September, 2013, it was approved by the FDA of the United States to be listed as Brintelix, which was used for the treatment of major depression in adults. In October of the same year, the application for marketing permission (MAA) of Voetixtine received positive opinions from the Committee of Medical Products for Human Use (CHMP) of the European Drug Administration (EMA), and CHMP suggested to approve Brintelix for the treatment of major depression (MDD) in adults.In December, 2013, the European Commission of EMA granted the marketing right of Voetixtin in the whole European Union. There are four listing specifications of Voetixetie: 5mg, 10mg, 15mg and 20mg. At present, the application for listing of Vortextine Hydrobromide has been submitted in many countries, but it has not been listed in China.

Vootixetin has high affinity with 5-HT receptor. Compared with duloxeting, Vootixeting can act on 5-HT3, 5-HT1A, 5-HT7, 5-HT1D and 5-HT1B receptors with high selectivity, while regulating mood, the dosage is small, the once-a-day administration scheme is simple, the patient's compliance is improved, and there are few drug interactions, high selectivity and few side effects. As a new antidepressant, Votisidine is considered to be the most successful drug in unipolar affective disorder research.

Name	Votioxtine hydrobromide
MF	C18H23BrN2S
MW	379.36
CAS	960203-27-4

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 2

Why Choose Us ？

1 、 Manufacturer supply, best price and service.

2、 Safe fast delivery.

3、 F ree sample.

4、 Large stock.

5、 Easy payment: bank transfer, moneygram, paypal....

6、 Good reputation, great feedback.

7、 Customers worldwide: Metrochem Api Pvt Ltd;Bdr Lifesciences Pvt.Ltd;Srini Chem;Eva Pharma;Pharmaffiliates Analytics&Synthetics(p)Ltd;....From India,Egypt,Canada ....

-Packing&Shipping-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 3

Ship methods	Special line	Express	By air	By sea
Ship methods	Special line	DHL/TNT/FeDex/UPS	By air	By sea
Delivery	7-15 days	3-10 days	3-5 days	10-30 days
Service	Door to door	Door to door	To airport	To seaport
Customs clearance	No	Possible	Yes	Yes

-Company Profile-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 4

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 5

About us:

Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixab a n, Lurasidon e , Bexagliflozin, Vortioxetine, L OXO -292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

-Certification- Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 6

Basic Info

Product Name:

Vortioxetine hydrobromide

Other Name:

Piperazine,1-[2-[(2,4-dimethylphenyl)thio]phenyl]-,hydrobromide (1:1);Lu AA 21004 hydrobromide;Vortioxetine hydrobromide;1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine hydrobromide;2361026-23-3

CAS No.:

960203-27-4

Molecular Formula:

C18H22N2S.BrH

InChIKeys:

InChIKey=VNGRUFUIHGGOOM-UHFFFAOYSA-N

Molecular Weight:

379.35762

Exact Mass:

378.076538

UNII:

TKS641KOAY

NCI Thesaurus Code:

C125653

ATC Code:

N06AX26

HScode:

29339900

Categories:

Nervous System Drugs

Characteristics

PSA:

40.6

XLogP3:

5.21610

See More Vortioxetine hydrobromide Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction H410 Very toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Vortioxetine hydrobromide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
3

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Certifications:
business license

Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nootropic Powder Vortioxetine Hydrobromide Vortioxetine HCl CAS No. 960203-27-4	100 G	Aug 31, 2023

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