2-(9-oxoacridin-10-yl)acetic acid
58880-43-6
Analytical Reagent
99%
qingdao
AIRUIKE
1kg
Yes
2024-08-19
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCridanimod Sodium is the sodium salt form of cridanimod, a small molecule that can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Upon intramuscular administration, cridanimod is able to induce the expression of PR in endometrial cancer. This could increase the sensitivity of endometrial cancer cells to progestin monotherapy. In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone (LH) release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen release from the ovaries. This leads to an inhibition of cellular growth in estrogen-dependent tumor cells. In addition, this agent is able to increase the production and release of interferon (IFN) alpha and beta. PR is often downregulated in endometrial cancer and makes it resistant to progestin-mediated hormone therapy.Basic Info
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Product Name:
2-(9-oxoacridin-10-yl)acetic acid
Other Name:10(9H)-Acridineaceticacid, 9-oxo-, sodium salt (1:1);10-Carboxymethyl-10H-acridine-9-one sodium salt;Camedone;Sodium 9-oxo-10-acridineacetate;10(9H)-Acridineacetic acid, 9-oxo-, sodium salt;9-Oxo-10(9H)-acridineacetic acid sodium salt;acridine sodium acetate;2-(9-oxoacridin-10-yl)acetic acid
CAS No.:58880-43-6
Molecular Formula:C15H11NO3
InChIKeys:InChIKey=DTBMZZDVZAZJNU-UHFFFAOYSA-N
Molecular Weight:0
Exact Mass:275.05583746
UNII:54W868ROLR
NCI Thesaurus Code:C114298
Categories:
Characteristics-
Melting Point:
360-370 °C
Critical Temperature & Pressure:Store at -20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
api,Intermediates,Organic Chemistry,Inorganic Chemistry,Daily Chemicals,Cosmetic Raw Materals
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Location:
Huangdao District, Qingdao City, Shandong Province (formerly Room 606-2, Building 1, No. 10 Beijing Road, Jiaonan City)
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Payment Terms:
TT against copy of documents,D/P,D/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2023
Company Certificates-
Credit rating certificate
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Hazardous Chemicals Business License
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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