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Clemastine fumarate CAS 14976-57-9 FAST DELIVERY 99% POWDER

Name: Clemastine fumarate CAS 14976-57-9 FAST DELIVERY 99% POWDER
Brand: Million
SKU: pr2407304809
Price: 2.5 USD
Availability: InStock

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Unit Price:

$2.5/KG EXW

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CAS No.:

14976-57-9

Grade:

Pharmaceutical Grade

Content:

99.78%

Port:

CHINA

Brand:

Million

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2100-12-31

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Jinan Million Pharmaceutical Co., Ltd

Company Type:

Manufactory

Location:

China

Payment Terms:

L/C,100% TT in advance

Average Lead Time:

3 days

Qualification:

Main Products:

Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

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Product Description
Seller Information

Description

Shop Apixaban CAS 503612-47-3 FACTORY supply-Detailed Image 1

-Product Descrition-

Description：An antihistamine with antimuscarinic and moderately sedative effects that can be used to relieve symptoms of allergic diseases such as rhinitis and urticaria.Chloramphenicl fumarat is a potent, long-lasting, fast acting, highly selective histamine H1 receptor antagonist that simultaneously blocks H1 receptors and antagonizes cytotoxicity. It is mainly used clinically for allergic skin diseases, allergic rhinitis, and other allergic diseases. Chloramine can be quickly and almost completely absorbed by the body, reaching a peak in blood concentration within 2-4 hours, and has the strongest antihistamine effect within 5-7 hours.

Описание：Антигистаминный препарат с антимускариновым и умеренно седативным действием, который может использоваться для облегчения симптомов аллергических заболеваний, таких как ринит и крапивница. Хлорамфеникл фумарат - это мощный, длительно действующий, быстродействующий, высокоселективный антагонист гистаминовых H1-рецепторов, который одновременно блокирует H1-рецепторы и антагонизирует цитотоксичность. В основном он используется в клинической практике для лечения аллергических заболеваний кожи, аллергического ринита и других аллергических заболеваний. Хлорамин быстро и почти полностью всасывается в организм, достигая пика концентрации в крови в течение 2-4 часов, и оказывает сильнейший антигистаминный эффект в течение 5-7 часов.

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 2

Why Choose Us ？

1 、 Manufacturer supply, best price and service.

2、 Safe fast delivery.

3、 F ree sample.

4、 Large stock.

5、 Easy payment: bank transfer, moneygram, paypal....

6、 Good reputation, great feedback.

7、 Customers worldwide: Metrochem Api Pvt Ltd;Bdr Lifesciences Pvt.Ltd;Srini Chem;Eva Pharma;Pharmaffiliates Analytics&Synthetics(p)Ltd;....From India,Egypt,Canada ....

-Packing&Shipping-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 3

Ship methods	Special line	Express	By air	By sea
Ship methods	Special line	DHL/TNT/FeDex/UPS	By air	By sea
Delivery	7-15 days	3-10 days	3-5 days	10-30 days
Service	Door to door	Door to door	To airport	To seaport
Customs clearance	No	Possible	Yes	Yes

-Company Profile-

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 4

Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 5

About us:

Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixab a n, Lurasidon e , Bexagliflozin, Vortioxetine, L OXO -292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.

-Certification- Shop Apixaban intermediates 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one CAS 536760-29-9-Detailed Image 6

ECHEMI Editorial Reference

Clemastine Fumarate is a selective histamine H1 receptor antagonist with IC50 of 3 nM.Target: Histamine H1 ReceptorClemastine Fumarate inhibits histamine induced rise in [Ca2+]i in HL-60 cells with an IC50 of 3 nM as compared with that of chlorpheniramine or diphenhydramine with IC50 values of 20 nM and 100 nM, respectively [1]. Clemastine showed a first-pass reduction in the extent of absorption, with oral bioavailability calculated as 39.2 +/- 12.4%. Extravascular distribution of drug

Certificates

Basic Info

Product Name:

Clemastine fumarate

Other Name:

Pyrrolidine,2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-,(2R)-,(2E)-2-butenedioate (1:1);Pyrrolidine,2-[2-[(p-chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methyl-,(+)-,fumarate (1:1);Pyrrolidine,2-[2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methyl-,[R-(R*,R*)]-,(E)-2-butenedioate (1:1);HS 592;Tavegil;(+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate;Clemastine fumarate;Clemastine hydrogen fumarate;Tavegyl;Agasten;Tavist;Meclastine fumarate;Mecloprodine;Telgin G;Lacretin;Kinotomin;Marsthine;Masletine;Inbestan;Lecasol;Maikohis;Piloral;Alphamin;Fuluminol;Mallermin F;Trabest;Xolamin;Anhistan;Aloginan;Reconin;Bravegyl;Telgin;52205-67-1

CAS No.:

14976-57-9

Molecular Formula:

C21H26ClNO.C4H4O4

InChIKeys:

PMGQWSIVQFOFOQ-YKVZVUFRSA-N

Molecular Weight:

459.96

Exact Mass:

459.181244

EC Number:

239-055-2

HScode:

2933990090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

87.1

XLogP3:

4.75410

Appearance:

white to beige

Density:

1.097 g/cm3

Melting Point:

177-178 °C

Boiling Point:

154 °C @ Press: 0.02 Torr

Flash Point:

211ºC

Refractive Index:

1.553

Water Solubility:

DMSO: soluble 5mg/mL (clear solution; warmed)

Storage Conditions:

Store at RT

Vapor Pressure:

1.94E-07mmHg at 25°C

Specific rotation:

D21 +16.9° (methanol)

Odor:

Odorless

See More Clemastine fumarate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Clemastine fumarate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Avanafil,Tirzepatide,Semaglutide,Pregabalin,Nootropics,MT2

Location:
Room 1-2208, Lianhecaifu Square, No2177, Tianchen Road, Gaoxin District, Jinan City, Shandong Province, China

Payment Terms:
L/C,100% TT in advance

Average lead Time:
3 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2012

Company Certificates
- business license
Founded in 2012, Jinan Million Pharmaceutical Co., Ltd (Jinan Milin Pharmaceutical Co., Ltd) is a modern pharmaceutical enterprise guided by innovation. Million pharm has excellent research and development capabilities and complete industrial bases with international quality management system. It is dedicated to the research, development, production and customization of pharmaceuticals and advanced pharmaceutical intermediates.

Jinan Million Pharmaceutical Co., Ltd has been focusing on the research of Cerebro-cardiovascular drugs, Central nervous system drugs, Anti-cancer drugs, Antibacterial drugs and others for 12 years; the products are: Apixaban, Lurasidone, Bexagliflozin, Votioxitine, Loxo-292/Selpercatinib, Baricitinib and intermediates. Million has worked with reputable customers, like METROCHEM API PVT LTD; BDR LIFESCIENCES PVT.LTD; INCETPAT PHARM; SRINI CHEM; EVA PHARMA; PHARMAFFILIATES ANALYTICS & SYNTHETICS (P) LTD; ....from India, Egypt, Canada...

Jinan Million Pharmaceutical Co., Ltd has a 1,500㎡ R&D center in the Zhongguancun E Valley (Qihe) Incubator, equipped with complete test equipment, such as high-performance liquid chromatography, nuclear magnetic resonance spectrometer, liquid chromatography mass spectrometer, automatic polarimeter, etc., which can meet the needs of various laboratory scale tests in different conditions. The pilot workshop is equipped with 50L and 100L glass reactors, high and low temperature equipment, etc., which can support organic chemical reactions at -100°C or 200°C. In addition, Million has a production site in Linyi city with many independent production lines, such as: production line of Apixabn intermediate 20 tons/year, production line of Lurasidon intermediate 10 tons/year, which can meet the commercial production of various products.

The technical team is composed of high-level talents in major of pharmacy, bio-pharmaceutical or chemical synthesis, of which 10% has doctor’s degree and 15% has master’s degree. The team members are young and energetic with innovative spirit and willing to overcome obstacles.

Jinan Million Pharmaceutical Co., Ltd adheres to the business philosophy of "dedication and innovation", insists on pioneering and innovating, constantly improves the quality system, and vigorously trains technical and management talents to build an elite team and serves customers better. Looking forward to cooperate with you for joint development and common progress.
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Clemastine fumarate CAS 14976-57-9 FAST DELIVERY 99% POWDER

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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