GMP TNJONE High Quality 99% High Purity Top Quality API Veterinary Medicine CAS123997-26-2 Eprinomectin

What is Eprinomectin  ?

Indications:
This product is a broad spectrum anti-parasite product. It is used for expelling parasites in the cow such as nematode in gastrointestinal tract, nematode in lung and epizoic parasites such as acarid, tick, louse, wrbles, mange mite.
Pharmacological actions
Eprinomectin has expelling effect on nematode and arthropod. Firstly it contributes to liberation of inhibitory neurotransmitter GABA from polypide and also contributes to openness of the chloridion channel controlled by glutamic acid to strengthen the permeability of neurilemma for chloridion and to forbid transferring nerve signal. Secondly it makes nerve paralyse and make muscles's cell lose shrinking power and finally it makes polypide die.
Character: White to gray-white powder, with hygroscopicity.
This product is not only the most active broad-spectrum antiparasitic agent of avermectins, but also one of these products with the lowest distribution coefficient. It can highly prevent and cure parastic nematodes in seven kinds of cattle and sheep. It is very safe.

• Eprinomectin is moderately used in ruminants, mainly in pour-ons and injectables. So far it is not used in swine, poultry or horses. Use in cats as a spot-on (in combination with other actives) is still rather scarce. So far it is not used in dogs.
  In most finished products, efficacy and safety depend not only on the amount of active ingredient(s) but also on their formulations (i.e. the type and amount of so-called inert ingredients), particularly in injectables and in topical pour-ons and spot-ons. These inert ingredients can significantly affect the pharmacokinetic behavior (e.g. absorption through the skin or from the injection site, distribution within the body, spreading throughout the body surface, etc.). Generic products usually contain the same amount of active ingredient(s) as the original product, but often in quite different formulations. In many cases, the curative (therapeutic) efficacy of the different formulations is quite comparable, but the protective (prophylactic) efficacy that determines the length of protection against re-infestations may be rather different.