China Most Professional Factory Supply High Qulity GS-441524 CAS no 1191237-69-0

  Product Information  

GS-441524 is a nucleoside analogue antiviral drug which was developed by Gilead Sciences. It is the main plasma metabolite of the antiviral prodrug remdesivir, and has a half-life of around 24 hours in human patients. Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis, a lethal systemic disease affecting domestic cats.

Product name	GS-441524
CAS No.	1191237-69-0
MF	C12H13N5O4
MW	291.26
EINECS No.	200-001-8
Melting point	> 233° C (dec.)
Boiling point	N/A
Density	1.84±0.1 g/cm3(Predicted)
Solubility	Soluble in DMSO (>25 mg/ml)
Storage	-20°C

 

Description

Items	Standard		Test Results
Identification	A.H-NMR:Comply with the structure		Complies
	B.LC-MS:Comply with the structure		Complies
	C.The IR spectrum of sample should be identical with that of reference standard.		Complies
	D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.		Complies
Loss on drying %	≤2.0		0.19
Heavy metals ppm	≤10		<10
Moisture %	≤1.0		0.1
Sulphated ash %	≤0.5 determined on 1.0 g.		0.009
Residue on ignition %	≤0.1		0.03
Related Substances %	Unspecified impurities: for each impurity	≤0.10	<0.10
	Total Impurity	≤0.5	0.18
Purity %	≥99.0		99.7
Assay %	99.0 ~101.0 (anhydrous substance).		99.8
Storage	Preserve in well-closed, light-resistant and airtight containers.		Complies

 

  About Product Technical Details  

CAS: 1191237-69-0 MF: C12H13N5O4 MW: 291.26 EINECS: 200-001-8 Product Categories: GS;API;Intermediates;API;3;1191237-69-0 Mol File: 1191237-69-0.mol GS-441524 Chemical Properties Melting point  > 233° C (dec.) density  1.84±0.1 g/cm3(Predicted) storage temp.  -20°C solubility  Soluble in DMSO (>25 mg/ml) pka 12.13±0.70(Predicted) form  solid color  Off-white Stability: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. InChI InChI=1/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/s3 InChIKey BRDWIEOJOWJCLU-QHRJDZJMNA-N SMILES C([C@]1(C2=CC=C3C(=NC=NN23)N)[C@@H]([C@H](O)[C@@H](CO)O1)O)#N |&1:1,12,13,15,r| CAS DataBase Reference 1191237-69-0

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