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Conjugated Estrogen

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CAS No.:

12126-59-9

Grade:

Pharmaceutical Grade

Port:

Any China Port

Packaging:

1 kgs/bag

Price valid (until):

2024-12-05

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

API,Intermediate

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Conjugated estrogens are a medicine that contains a mixture of estrogen hormones. It is used to treat moderate to severe hot flashes, changes in and around the vagina, and other symptoms of menopause or low amounts of estrogen (hypoestrogenism). This medicine is also used to prevent osteoporosis (thinning of the bones) after menopause.

    Before Using

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies on the relationship of age to the effects of conjugated estrogens have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medication in teenagers are not expected.

    Geriatric

    Although appropriate studies on the relationship of age to the effects of conjugated estrogens have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have breast cancer, stroke, or dementia, which may require caution in patients receiving conjugated estrogens.

    Breastfeeding

    Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

    Drug Interactions

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    • Amifampridine
    • Bupropion
    • Cosyntropin
    • Donepezil

    Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

    • Etoricoxib
    • Ginseng
    • Levothyroxine
    • Licorice
    • Tipranavir

    Basic Info
    Product Name:

    Estrogens, conjugated

    Other Name:

    Estrogens,conjugated;Estrogens,conjugates;Presomen;Conjugates,estrogens;Premarin;Conjugated estrogens;Cenestin;Azumon;C.E.S.;Climarest;Conjugen;Dagynil;Emopremarin;Ayerogen Crema Vaginal;Femavit;Hyphorin;Mannest;Menopak E;Menpoz;Neo-Menovar;Equin;Ovest;Premaril;Premarin Crema V;Premarin Creme;Premarin Vaginal Creme;Premarina;Premarose;Prevagin-Premaril;Romeda;Sefac;Srogen;Sukingpo;Transannon;Oestro-Feminal;Ayerogen;Conjugated equine estrogen

    CAS No.:

    12126-59-9

    InChIKeys:

    JKKFKPJIXZFSSB-CBZIJGRNSA-N

    Molecular Weight:

    370.4

    Exact Mass:

    370.085083

    EC Number:

    235-199-5

    UNII:

    7XY8FW3E68

    DSSTox ID:

    DTXSID00872961

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    91.88000

    XLogP3:

    3.95170

    Appearance:

    Solid

    Melting Point:

    254.5°C

    Storage Conditions:

    Commercially available conjugated estrogens USP tablets, synthetic conjugated estrogens A tablets, synthetic conjugated estrogens B tablets, and conjugated estrogens USP vaginal cream should be stored at controlled room temperature (20-25 °C). Conjugated estrogens USP powder for injection should be stored at a temperature of 2-8 °C prior to reconstitution. Following reconstitution, solutions of the drug should be used immediately.

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    Carcinogenicity, Category 1B

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    H350 May cause cancer

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    API,Intermediate

    Payment Terms:

    TT against copy of documents,L/C

    Average lead Time:

    30

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    201-300

    About Echemi Pharmaceutical 

    Echemi’s philosophy is to seek for higher quality, to explore frontier area. The progress of human society, the extension of life expectancy, and the conquest of disease are all derived from the numerous businesses and individuals who have quietly dedicated themselves in the pharmaceutical industry. It’s the controlling of supply chain quality that ensures the efficacy. It’s the continuous exploration that promotes the development of the pharmaceutical industry and benefits more future generations. The pursuit of high quality requires all partners of Echemi Pharmaceutical to be screened, whether its certificate, qualification or scale. In the field of renewal, we will embrace all new changes and make more contributions to the development of pharmaceutical industry.

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    Advantage for Pharmaceutical 

    • Having been working in pharmaceutical field for more then 15 years, we have experienced regulatory team, quality control team, sourcing team, technical support team, and logistics team. And we are familiar with the regulatory requirements from different areas, can offer tailored service for our customers.

    • We have hundreds of strategic partners for APIs, intermediates, and custom synthesis. All of our partners are ready to support our customers with documents, and be audited.

    • We can offer custom synthesis for some new chemical structures and some materials which there are no reliable suppliers.

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    Product Category 

    We care for human and animal health and we are committed to creating a better social environment.

    •  Human API

    • Intermediate

    • Veterinary API

    • Agrochemical

    • Fine Chemical

    • Custom Synthesis



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