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Hexapeptide-11

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

161258-30-6

Port:

济南

Packaging:

100g 1kg 10kg 25kg 100kg

Price valid (until):

2024-12-20

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

semaglutide intermediates,tirzepatide intermediate,degludec intermediate,insulin detemir,retatrutide intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Hexapeptide-11;(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid;L-Proline, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-;H-Phe-Val-Ala-Pro-Phe-Pro-OH


    Pentamide-6, or Hexapeptide-11, was originally isolated from Saccharomyces yeast fermentation. Pentamide-6 directly affects dermal cell senescence by downregulating key genes involved in apoptosis. The cellular proteins ataxia telangiectasia mutated (ATM) and p53 have been shown to be hyperactive in degenerative aging pathologies, leading to cellular senescence. Senescent cells in skin can cause dermal thinning, loss of subcutaneous fat, decreased hair growth, and slower wound healing. Pentamide-6 is a hexapeptide with the structure Phe-Val-Ala-Pro-Phe-Pro (FVAPFP). This oligopeptide helps promote younger looking skin by reversibly downregulating ATMP and p53 at peptide concentrations of 0.1%–1.0%. By targeting the cellular aging process, FVAPFP has been shown to modulate senescence in both intrinsically and extrinsically aged fibroblasts, as well as extrinsically aged dermal papillae cells in vitro. This signal oligopeptide has been shown to increase fibrillogenesis through growth factors, and ECPs increase transmembrane and cell shock proteins, and promote hair growth. A clinical trial conducted on 25 subjects showed its ability to increase skin elasticity and reduce deformity in facial skin.
    Items Specifications






    Basic Info
    Product Name:

    Hexapeptide-11

    Other Name:

    Hexapeptide-11;(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid;L-Proline, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-;H-Phe-Val-Ala-Pro-Phe-Pro-OH

    CAS No.:

    161258-30-6

    Molecular Formula:

    C36H48N6O7

    InChIKeys:

    GFEYWOGCSROPRT-OBXVVNIGSA-N

    Molecular Weight:

    676.8

    Exact Mass:

    676.35844789

    EC Number:

    000-000-0

    UNII:

    NCJ63WU6BY

    DSSTox ID:

    DTXSID90648379

    Color/Form:

    White to off-white

    Characteristics
    Density:

    1.269±0.06 g/cm3(Predicted)

    Boiling Point:

    1035.1±65.0 °C(Predicted)

    PKA:

    3.43±0.20(Predicted)

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    semaglutide intermediates,tirzepatide intermediate,degludec intermediate,insulin detemir,retatrutide intermediate

    Location:

    Leize Road, Juancheng County, Heze City, Shandogn Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    20

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    101-200

    Year of Establishment:

    2020

    Certifications:

    is9001

    Shandong Juntai Pharmaceutical Co., LTD. is a high-tech enterprise engaged in the research and manufacture of medicine, cosmetics, food and health care products. Our main product is widely used in the field such as medicine, cosmetics and food and health products. The management team is made up of members from well-known Chinese universities or pharmaceutical companies, now we have established partnerships with most domestic and foreign pharmaceutical companies, such as Gilead Science and so on.Company Profile

    Since establishment, we keep the rapid development, at present,  set up Research and development center on  DIYA double inovation garden, jinan city. Sales company -Jinan Wanxiang chemical products co., LTD is located in tongke new drug research and development base, shun feng road, jinan high-tech zone. Production base is located in YiCheng economic development zone , ZaoZhuang city.

    At present, the company's main products are new pharmaceutical API and advanced intermediates series, cosmetics active ingredients series. The dominant products are unnatural amino acids, long chain binary fatty acids and short peptides.

    In the future, as a science and technology enterprise, according to the idea of"thinking altruistic", we keep to serve customers with continuous innovation service, with better quality and stable product supply. And strive to contribute our Juntai people's wisdom and love to the society and the people. Internally, we pursue the happiness of all employees. At the same time, we follow the management policy of "green, safe and intelligent manufacturing", constantly promote the production and scientific research to be more green, energy-saving and scientific, and undertake the obligations of occupational environment health and safety.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Canada

    Hexapeptide-11

    25 KG Jan 6, 2026
    Post an enquiry for this product
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