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99% Purity Mazdutide in Stock cas 2259884-03-0

5 Inquiries

Unit Price:

$100-120/G FOB

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CAS No.:

2259884-03-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

guangzhou

Brand:

Packaging:

10mg/vial,10vials/box

Sample Available:

Yes

Price valid (until):

2027-03-31

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Changsha Duole Technology Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,TT against B/L draft before shipment

Average Lead Time:

2 days

Qualification:

Main Products:

Tirzepatide,Retatrutide,Semaglutide,Cagrilintide,NAD+,Bacteriostatic wate

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Product Details
Seller Information
History Price
Inquiry History

Description

Product Detail

Name:Mary

Whatsapp:+86 152 2772 7503

Email Address:sales1@xttch.com

Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).

Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.

In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.

Name	Retatrutide
CAS RN	2381089-83-2
Solubility	Dissolved in dimethyl sulfoxide
Storage condition	-20°C
EINECS	200-001-8

Appearance: Powder

Purity: >99% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Company profile

Changsha Duole Technology Co., Ltd was established in 2020 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures.

With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

Its core team is composed of technical experts in the fields of pharmaceutical engineering, fermentation engineering and protein engineering. The company has built a 3,300-square-meter recombinant drug research and development center in Shibei, Yuelu District, Changsha City. It has a complete pharmaceutical engineering, preparation and quality research system and talent team, and has built a GMP workshop to meet the international market API supply and CDMO services.

At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.

Why choose us

Our company has independent factories, mass production of pharmaceutical intermediates, organic intermediates and other raw materials, widely used in medicine, health care products, cosmetics, nutritional supplements, food additives and other fields.

Our company adheres to the business philosophy of integrity and cooperation. scientific innovation and service first.With absolute quality assurance as the purpose and perfect service system as the basis, our company provides efficient and satisfactory consulting services, sincerely welcomes your business inquiries,and looks forward to working with you to create a new future.

Key Products:
Our primary focus encompasses a range of products, including weight loss peptides, medicinal peptides, cosmetic peptides, and customized peptides. Notable among our weight loss peptide offerings are Semaglutide, Tirzepatide, Retatrutide, and others.

Certificates

ECHEMI Editorial Reference

Mazdutide is a peptide-based GLP-1 and glucagon receptor (GCGR) dual agonist. As a pharmaceutical raw material, Mazdutide is characterized by its dual receptor activity and defined peptide structure. It is suitable for API research, analytical testing, pharmaceutical development, and related manufacturing processes.

Basic Info

Product Name:

Mazdutide

Other Name:

Mazdutide;Mazdutide acetate;Mazdutide 10mg;Mazdutide 5mg 10mg;LY-3305677;Mazdutide (IBI-362;OXM-3)

CAS No.:

2259884-03-0

Molecular Weight:

EC Number:

884-103-0

Color/Form:

White to off-white

Categories:

Bulk Drug Intermediates

Research

Class:

Dual GLP-1R/GCGR agonist (long-acting peptide)

Status:

Investigational — Phase 3 (China)

Mechanism:

A long-acting dual agonist of the GLP-1 receptor (GLP-1R, Ki = 28.6 nM) and glucagon receptor (GCGR, Ki = 17.7 nM). The dual activation provides both glycemic control (via GLP-1R) and increased energy expenditure / hepatic lipolysis (via GCGR), producing weight loss beyond what GLP-1R agonism alone achieves.

EC50 (GLP1R Ki):

28.6 nM

EC50 (GCGR Ki):

17.7 nM

Source:

GlpBio: Mazdutide (CAS 2259884-03-0); Innovent Phase Ib results (eClinicalMedicine 2022).DOI

Clinical Development:

NCT04930343; NCT05592656

References

PubChem:

PubChem

Literature:

GlpBio: Mazdutide (CAS 2259884-03-0); eClinicalMedicine: Innovent Phase Ib results (2022); ClinicalTrials.gov: DREAMS-1 (NCT04930343)

Disclaimer:

Mazdutide is NOT FDA-approved or EMA-approved. It is in Phase 3 clinical trials in China. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

Seller Information

Business Type:
Trader

Main Products:
Tirzepatide,Retatrutide,Semaglutide,Cagrilintide,NAD+,Bacteriostatic wate

Location:
Jinxing Middle Road, Xihu Street, Yuelu District, Changsha City, Hunan Province

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment

Average lead Time:
2 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2023

Changsha Duole Technology Co., Ltd

Changsha Duole Technology Co., Ltd was established in 2020 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures.

With synthetic biology platform technology as the core, it conducts innovative research and development, mainly engaged in the research and development of recombinantly expressed pharmaceutical peptides and proteins. Its products include innovative drugs, APIs, pharmaceutical and green synthetic industrial enzymes, functional peptides and protein products, etc.

Its core team is composed of technical experts in the fields of pharmaceutical engineering, fermentation engineering and protein engineering. The company has built a 3,300-square-meter recombinant drug research and development center in Shibei, Yuelu District, Changsha City. It has a complete pharmaceutical engineering, preparation and quality research system and talent team, and has built a GMP workshop to meet the international market API supply and CDMO services.

At present, our company has realized the industrialization of a variety of biosynthetic peptide products and has obtained cooperation orders from many well-known domestic and foreign pharmaceutical companies.
Weekly Price

 The chart shows the price trend of the product in the past 12 months.

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Mazdutide	25 MG	Aug 12, 2026
Nigeria	Mazdutide 10mg	20 PCS	Mar 7, 2026
United Kingdom	Mazdutide	1 KG	Feb 10, 2026
United States	Mazddultide cas	2 MT	Nov 14, 2025
United States	Mazdutide	30 MG	Jul 15, 2024

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99% Purity Mazdutide in Stock cas 2259884-03-0

Product Details

Seller Information

History Price

Inquiry History

Name

Retatrutide

CAS RN

2381089-83-2

Solubility

Dissolved in dimethyl sulfoxide

Storage condition

-20°C

EINECS

200-001-8

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