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GS-4415241191237-69-0 buy - large image1
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GS-4415241191237-69-0

50 Inquiries

Unit Price: Get Latest Price
CAS No.:

1191237-69-0

Port:

shanghai

Packaging:

1kg/bag

Price valid (until):

2024-12-21

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


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    Items Specifications





    ECHEMI Editorial Reference
    GS-441524 is a nucleoside analogue that terminates the RNA chain of viral RNA-dependent RNA polymerase. GS-441524 was developed by Gilead Sciences, Inc as part of their research into human RNA virus disease such as Ebola. GS-441524 is a small molecule that exhibits potent antiviral activity against a number of RNA viruses, including the zoonotic severe acute respiratory syndrome (SARS) coronavirus ( Cho et al., 2012).
    GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as a drug metabolite, an antiviral agent and an anticoronaviral agent. It is a pyrrolotriazine, a nitrile, a C-nucleoside and an aromatic amine.|GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.

    Basic Info
    Product Name:

    GS-441524

    Other Name:

    (2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furancarbonitrile;GS-441524;GS441524;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;GS-441524 solution;EVO984;EVO 984;EVO-984;GS 441524

    CAS No.:

    1191237-69-0

    Molecular Formula:

    C12H13N5O4

    InChIKeys:

    BRDWIEOJOWJCLU-LTGWCKQJSA-N

    Molecular Weight:

    291.26

    Exact Mass:

    291.096754

    UNII:

    1BQK176DT6

    Categories:

    Respiratory Drugs

    Characteristics
    PSA:

    150

    XLogP3:

    -1.27552

    Density:

    1.84±0.1 g/cm3(Predicted)

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

    Location:

    hisense intelligence valley,no 2116,of phoenix road

    Payment Terms:

    TT against copy of documents,D/P,L/C

    Average lead Time:

    7

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

     SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful “Spring City”-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of “Integrity management,Quality controlling and Customer orientation”.  Web : www.chinalookchemical.com 

        We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.

  • Inquiry History
    50 Inquiries
    Country Product Purchase Quantity Date Posted
    Switzerland

    GS-441524 Liquid CAS 1191237-69-0 Hot selling Overseas stock

    10000 MT Sep 13, 2023
    Turkey

    GS441524 powder CAS 1191237-69-0 Remdesivir GS-5734 Alprostadil pge

    1 PCS Jan 6, 2026
    Bulgaria

    Lowest price in the whole network 1191237-69-0 GS-441524

    100 BOU Nov 8, 2023
    United States

    GS441524 CAS 1191237-69-0 Cat Fip GS441 liquid 20mg 30mg 6ml 8ml 10ml

    4 MT Oct 18, 2023
    China

    GS 441524

    1 KG Dec 5, 2023
    Thailand

    gs-441524

    4 G Jan 16, 2026
    United States

    GS-441524

    20 KG Jan 9, 2026
    Germany

    Ga 441524

    100 G Oct 9, 2025
    Brazil

    GS441524

    1 KG Aug 6, 2025
    Pakistan

    GS-441524

    1 KG Aug 4, 2025
    Pakistan

    gs 441524

    1 KG Oct 6, 2024
    Turkey

    gs441524

    1 KG Jul 16, 2024
    India

    GS441524

    100.00 KG May 13, 2024
    Turkey

    GS-441524

    100 G Mar 10, 2024
    Poland

    GS-441524

    16  Jan 2, 2024
    Mexico

    Fip Cat Gs-441524 Fipv

    1 KG Jul 3, 2026
    Malaysia

    Gs-441524

    10 MG Jun 15, 2026
    China

    GS-441524

    1680 MG May 2, 2026
    Poland

    GS-441524

    100 G Feb 25, 2026
    Poland

    GS-441524

    1 KG Feb 25, 2026
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