High Purity API Raw Material Powder Nevirapine CAS:129618-40-2
129618-40-2
Pharmaceutical Grade
99%
shenzhen
1kg/bag;25kg/Cardboard Drum
2025-01-31
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCrystalline SolidChEBI: A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse tr nscriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.Nevirapine (Viramune) is more than 90% absorbed by theoral route and is widely distributed throughout the body. Itdistribute
Solid
Nevirapine is a dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse transcriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is a dipyridodiazepine and a member of cyclopropanes.|A potent, non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with nucleoside analogues for treatment of Human Immunodeficiency Virus Type 1 (HIV-1) infection and AIDS. Structurally, nevirapine belongs to the dipyridodiazepinone chemical class.|Nevirapine is a Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor. The mechanism of action of nevirapine is as a Non-Nucleoside Reverse Transcriptase Inhibitor, and Cytochrome P450 3A Inducer, and Cytochrome P450 2B6 Inducer.|Nevirapine is a nonnucleoside reverse transcriptase inhibitor used in combination with other agents in the therapy of human immunodeficiency virus (HIV) infection and the acquired immune deficiency syndrome (AIDS). Nevirapine is associated with a high rate of serum aminotransferase elevations during therapy and is a well established cause of acute, clinically apparent liver injury.|Nevirapine is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preventing the damage to the immune system and reducing the risk of developing AIDS.|A potent, non-nucleoside reverse transcriptase inhibitor used in combination with nucleoside analogues for treatment of HIV INFECTIONS and AIDS.Basic Info-
Product Name:
Nevirapine
Other Name:6H-Dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one,11-cyclopropyl-5,11-dihydro-4-methyl-;11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one;BI-RG 587;Nevirapine;Nevarapine;Viramune;NSC 641530;NVP;11-Cyclopropyl-4-methylDipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one;339524-51-5
CAS No.:129618-40-2
Molecular Formula:C15H14N4O
InChIKeys:InChIKey=NQDJXKOVJZTUJA-UHFFFAOYSA-N
Molecular Weight:266.3
Exact Mass:266.30
EC Number:1312995-182-4
UNII:99DK7FVK1H
NSC Number:759902|641530
DSSTox ID:DTXSID7031797
NCI Thesaurus Code:C29277
Color/Form:Crystals from pyridine and water
ATC Code:J05AG01|J - Antiinfectives for systemic use
HScode:29339900
Categories:
Characteristics-
PSA:
58.1
XLogP3:2
Appearance:white to tan
Density:1.1300 (rough estimate)
Melting Point:247-249 °C
Boiling Point:409.5°C (rough estimate)
Flash Point:9℃
Refractive Index:1.6200 (estimate)
Water Solubility:DMSO: ≥22mg/mL
Storage Conditions:-20°C Freezer
Vapor Pressure:3.4X10-9 mm Hg @ 25 deg C /Estimated/
Henrys Law Constant:Henry's Law constant = 3.3X10-17 atm-cu m/mol @ 25 °C /Estimated/
Dissociation Constants:pKa = 2.8
Experimental Properties:Hydroxyl radical reaction rate constant = 6.4X10-11 cu cm/molec-sec @ 25 °C /Estimated/
Hazard IdentificationClassification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) H412 Harmful to aquatic life with long lasting effects
Precautionary statement(s) Prevention P273 Avoid release to the environment.
Response none
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Estradiol,Progesterone,GS441524,4-Butylresorcinol,DeoxyArbutin,Coenzyme Q10
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Location:
XINYUAN DADUHUI PHASE 1, NO.258 TAOYUAN NORTH ROAD, LIANHU DISTRICT, XI 'AN , SHAANXI CHINA
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Payment Terms:
TT against copy of documents,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
11-50
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Year of Establishment:
2023
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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