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Rifapentine 100%

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CAS No.:

61379-65-5

Grade:

Pharmaceutical Grade

Content:

100%

Port:

HANGZHOU

Brand:

Hyper Chem

Packaging:

1/CTNS

Price valid (until):

2025-01-26

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Name

    Rifapentine

    CAS number

    61379-65-5

    Synonym

    Rifapentine; DL 473; DL-473; DL473; R 773; R-773; R773;

    Molecular Formula

    C47H64N4O12

    Molecular Weight

    877.040

    Appearance

    Bright red crystallinepowder

    Quality Standard

    API QC

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Stock Solution Storage

    0 - 4 C for short term (days to weeks), or -20 C for long term (months).

    Commercial package

    Medical plastic bottle

    Origin

    China

    Rifapentine More Info

    Rifapentine (also known as Rifapentine) is a long-acting rifamycin-class antibiotic, which is a cyclopentyl derivative of rifamycin. It is primarily used to treat infections caused by Mycobacterium tuberculosis and other related bacteria. Rifapentine works by inhibiting the β-subunit of the DNA-dependent RNA polymerase in susceptible bacteria, thereby suppressing bacterial RNA synthesis and exhibiting a broad-spectrum of antimicrobial activity, particularly against most Gram-positive and Gram-negative bacteria (including Pseudomonas aeruginosa) and especially Mycobacterium tuberculosis.

    The uses of Rifapentine mainly include:

    In combination with other anti-tuberculosis drugs for the treatment of various types of tuberculosis, including initial and retreatment cases.Suitable for use in directly observed short-course chemotherapy under the supervision of medical personnel.

    Also used in the treatment of non-tuberculosis mycobacterial infections.

    In combination with other anti-leprosy drugs, it may be effective in the treatment of leprosy.

    One of the characteristics of Rifapentine is its long half-life, which allows it to be used in intermittent therapy, potentially improving patient compliance and reducing the development of drug resistance. Additionally, Rifapentine has strong bactericidal activity against Mycobacterium tuberculosis in vitro, and Mycobacterium leprae and other mycobacteria are also sensitive to this drug. In the treatment of tuberculosis, Rifapentine is often used in combination with other drugs such as isoniazid, pyrazinamide, and ethambutol to enhance therapeutic efficacy.

    Certificates

    Basic Info
    Product Name:

    Rifapentine

    Other Name:

    Rifamycin,3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-;2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan,rifamycin deriv.;3-[[(4-Cyclopentyl-1-piperazinyl)imino]methyl]rifamycin;Rifamycin AF/ACPP;DL 473;Antibiotic DL 473IT;Rifapentine;MDL 473;Cyclopentylrifampicin;R 77-3;KTC 1;Priftin;Rifapentin;Prifitin;71950-35-1;773848-08-1

    CAS No.:

    61379-65-5

    Molecular Formula:

    C47H64N4O12

    InChIKeys:

    InChIKey=WDZCUPBHRAEYDL-LYDPARFQSA-N

    Molecular Weight:

    877.03

    Exact Mass:

    877.03

    EC Number:

    262-743-9

    UNII:

    XJM390A33U

    DSSTox ID:

    DTXSID8041115

    NCI Thesaurus Code:

    C66516

    ATC Code:

    J - Antiinfectives for systemic use

    HScode:

    2941903000

    Characteristics
    XLogP3:

    4

    Density:

    1.4±0.1 g/cm3

    Melting Point:

    179-180 °C

    Flash Point:

    540.0±34.3 °C

    Refractive Index:

    1.625

    Water Solubility:

    methanol: soluble2mg/mL, clear, red to red-brown

    Storage Conditions:

    -20°C Freezer

    Toxicity:

    LD50 in mice (mg/kg): >2000 orally; 750 i.p. (Cricchio); LD50 in mice (mg/kg): 3300 orally; 710 i.p. (Aroli)

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Rifapentine

    1.00 MT Jun 24, 2024
    Post an enquiry for this product
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