Factory Direct Supply High Quality 99% Purity Vonoprazan fumarate 1260141-27-2

  Product Detail  

Function&Application:

• 1. Compared with traditional proton pump inhibitor Lansoprazole, Vonoprazan acts by competitive and reversible inhibition of K+ in proton pump. Clinical and animal experiments have shown that Vonoprazan acts faster than PPI or H2 blockers, has a stronger effect on increasing pH, can rapidly relieve digestive tract symptoms, and restore enzyme activity after digestion. Few adverse reactions, several clinical trials have confirmed that Onorazan has a significant therapeutic effect on erosive esophagitis, prevention and treatment of gastric and duodenal ulcers, and eradication of Helicobacter pylori as a first-line treatment, the efficacy is higher than lansoprazole, and the adverse reactions are small. 2, Vonorazan has high lipophilicity, high dissociation constant Chemicalbook, and does not require acid activation to take effect in an acidic environment. Vonorazan inhibits the proton pump without acid activation and enters the stomach in high concentrations, producing the greatest inhibitory effect on the first dose and lasting for 24 hours. Vonorazan is stable in acid, and can rapidly increase the pH value in the stomach, exerting an acid inhibitory effect. 3. At the therapeutic dose, Vonorazan has little effect on other enzymes, little effect on physiological function of the body, good safety, and easier to tolerate. Traditional PPI is metabolized by CYP2C19, while Vonorazan is not mainly metabolized by CYP2C19, and the efficacy and effective dose are not significantly different in different patients, which can better meet the individualized medication regimen of patients.

Our advantage ：

★ The company has been established for more than 10 years with      rich export experience and experienced transportation team.

★ Awesome after sales.1 to 1 customer service to solve any problems from the beginning of the inquiry to the receipt of goods

★ Quality is guaranteed.

 Shipping Advise

1. By Express 

------Suitable for under 50kg, Fast:3-7 days.

High cost; Door to door service. Easy to pick up the goods.

2. By Air 

------Suitable for more than 50 kg, Fast:3-7 days,

High cost, airport to airport. professional broker needed.

3. By sea

------Suitable for more than 500kg. Slow: 5-45 days,

Low cost. Port to Port, professional broker needed.

                                                                                                            Service

1. Any inquiries will be replied within 24 hours.

2. Dedication to quality, supply & service.

3. Strictly on selecting raw materials.

4. OEM/ODM Available.

5. Reasonable & competitive price, fast lead time.

6. Sample is available for your evaluation & formulation development.