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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > S-Adenosyl-L-methionine for Sale > CAS 29908-03-0 S Adenosyl L Methionine /Sam-E/S-Adenosyl-L-Methionine with good price
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CAS 29908-03-0 S Adenosyl L Methionine /Sam-E/S-Adenosyl-L-Methionine with good price

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Unit Price: Get Latest Price
CAS No.:

29908-03-0

Grade:

Food Grade

Content:

99%

Port:

QINGDAO

Brand:

HM

Packaging:

1kg ,25kg or according to customer's detail requirement.

Price valid (until):

2025-04-30

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment
Average Lead Time:
5 days
Qualification:
Main Products:

Propylene glycol

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  



    CAS 29908-03-0 S Adenosyl L Methionine /Sam-E/S-Adenosyl-L-Methionine


    Shop Pharmaceutical Intermediate CAS 24729-96-2 Clindamycin Phosphate Powder-Detailed Image 1

    What is  Sam-E /S-Adenosyl-L-Methionine ?

    S-Adenosyl-L-methionine (also called S-adenosyl methionine, S-adenosylmethionine, SAMe, or SAM-e in the United States or ademetionine in Europe, and also often abbreviated as SAM and AdoMet) is a chemical that is found naturally in the body. SAMe is sold in the United States as a dietary supplement.

    S-Adenosyl-L-methionine was discovered in the early 1950s. It's made in the body from methionine, an amino acid found in foods. It has been found to regulate key functions in living cells.

    Abnormal levels of S-Adenosyl-L-methionine in the body have been reported in liver diseases and depression. This prompted researchers to investigate whether S-Adenosyl-L-methionine might be helpful in treating these conditions. The idea that S-Adenosyl-L-methionine might be helpful for osteoarthritis came from studies of S-Adenosyl-L-methionine for depression. Some of the participants in the depression studies who also had osteoarthritis said their joint symptoms improved when they took S-Adenosyl-L-methionine.

    Items Specifications
    Product name Sam-E /S-Adenosyl-L-Methionine
    CAS No. 29908-03-0
    MF C15H22N6O5S
    MW 398.44
    EINECS.No 249-946-8
    Appearance White crystal Powder
    Shelf Life 2 Years When Properly Stored
    Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.


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    Certification 

    Item Test S tandard Testing R esult
    Appearance 99% Complies
    Color White Powder Complies
    Particle Size 100% pass 80 mesh Complies
    Oder Characteristic Complies
    Taste Characteristic Complies
    Loss on Drying ≤5.0% 2.20%
    Residue on Ignition ≤0.1% 0.05%
    Residual  ≤0.1% Complies
    Residual Ethanol ≤0.5% Complies
    Heave Mentals ≤10ppm Complies
    Na ≤0.1% <0.1%
    Pb ≤3 ppm Complies
    Total Plate <1000CFU/g Complies
    Yeast & Mold <100 CFU /g Complies
    E. Coli Negative Complies
    Salmonella Negative Complies



    Function:

    (1) S-Adenosyl methionine is a good nutrition for the liver,can prevent alcohol, drugs and the liver-cell injury;

    (2) S-Adenosyl methionine has remarkable preventive effects on chronic active hepatitis, and other factors caused liver injury,heart disease, cancer and so on.

    (3) S-Adenosyl methionine has been found to be as effective as pharmaceutical treatments for arthritis and major depression as well.   

    (4)In the United States, SAM is sold as a nutritional supplement under the marketing name SAM-e (also spelled SAME or SAMe). Some research has indicated that taking SAM on a regular basis help fight depression, liver disease, and the pain of osteoarthritis. Multiple clinical trials indicate benefits for depression, some liver conditions and osteoarthritis. All other indications are not yet provent.


    Application:

    S-adenosine-L-methionine (SAM) and glutathione (GSH) are two important biologically active molecules in the organism. SAM, also known as adenosylmethionine, is the active form of methionine, which exists widely in animals and plants. It is composed of the substrate L-methionine and adenosine triphosphate (ATP) through S-adenosylmethionine. Synthetase (ECC2.5.1.6) is synthesized enzymatically. SAM is closely related to many metabolic processes in the human body. It is a biochemical drug that improves cell metabolism. It can increase the levels of GSH, sulfate and taurine in the liver through transsulfide groups, and prevent hepatitis, fatty liver, liver fibrosis, and cirrhosis. And liver cancer, it can also prevent alcohol, drugs and cytokines from damaging the liver.


    Recommended Storage:
    SAME is recommended to store it in a cool, dry place, sealed from outside air. We ship the product in a double sealed bag which can be resealed. Another container is recommended sealing from outside air.


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    ECHEMI Editorial Reference
    Ademetionine is an intermediate metabolite of methionine. Its involvement in methylation assists in cellular growth and repair, maintains the phospho-bilipid layer in cell membranes. It also helps in the maintenance of the action of several hormones and neurotransmitters that affect mood.
    S-adenosyl-L-methioninate is a sulfonium betaine that is a conjugate base of S-adenosyl-L-methionine obtained by the deprotonation of the carboxy group. It has a role as a human metabolite. It derives from a L-methioninate. It is a conjugate base of a S-adenosyl-L-methionine.|Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)

    Certificates
    • CAS 29908-03-0 S Adenosyl L Methionine /Sam-E/S-Adenosyl-L-Methionine with good price Certificates 1 TDS

    Basic Info
    Product Name:

    S-Adenosyl-L-methionine

    Other Name:

    Adenosine,5′-[[(3S)-3-amino-3-carboxypropyl]methylsulfonio]-5′-deoxy-,inner salt;Adenosine,5′-[(L-3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-,hydroxide,inner salt;Adenosine,5′-[(3-amino-3-carboxypropyl)methylsulfonio]-5′-deoxy-,hydroxide,inner salt,(3S)-;Methionine,S-adenosyl-;S-Adenosylmethionine;S-Adenosyl-L-methionine;L-Methionine,S-adenosyl-;L-S-Adenosylmethionine;Ademetionine;SAMe;Adenosyl-L-methionine;Active methionine;S Amet;Donamet;AdoMet;Transmetil;SAM;SAH (S-Adenosylmethionine);S-Adenosyl methionine;2613-02-7;5134-37-2;23095-97-8;28378-99-6;86522-35-2;86866-89-9

    CAS No.:

    29908-03-0

    Molecular Formula:

    C15H22N6O5S

    InChIKeys:

    InChIKey=MEFKEPWMEQBLKI-AIRLBKTGSA-N

    Molecular Weight:

    400.45

    Exact Mass:

    398.13723900 g/mol

    EC Number:

    249-946-8

    UNII:

    6EZ5466ZUX|K093C397UL

    DSSTox ID:

    DTXSID6032019|DTXSID20110014|DTXSID40169160|DTXSID40436187

    ATC Code:

    A - Alimentary tract and metabolism

    HScode:

    2934999090

    Characteristics
    PSA:

    547.02000

    XLogP3:

    -0.26280

    Melting Point:

    247-249ºC

    Boiling Point:

    78

    Storage Conditions:

    -20°C

    Collision Cross Section:

    184.5 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|186.46 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|184 Ų [M]+ [CCS Type: TW, Method: calibrated with polyalanine]|185.7 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|185.6 Ų [M+H]+

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Propylene glycol

    Location:

    No .41 Optics Valley Avenue, East Lake High-tech Development Zone, Wuhan ,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment

    Average lead Time:

    5 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2024

    Nanjing Huaman Import and Export Co., Ltd was established in 2024 with strong research and development capabilities and superb synthesis technology, as well as advanced quality control measures. Effectively promote the joint venture and cooperation with the major enterprises, manufacturers, with the idea of industrial development to serve the society and the majority of users. We always adhere to the market demand as the orientation, constantly synthesizing new high-tech chemical products , mainly exported to the United States, Europe, India, South Africa, Nigeria and other countries and regions, has a wealth of export experience, to ensure transportation safety, can let each customer as soon as possible to safely receive the goods.
  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    S-adenosyl-L-methionine

    5 MT Feb 14, 2025
    Post an enquiry for this product
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