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Pure Nimesulide buy - large image1
Pure Nimesulide buy - image1

Pure Nimesulide

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

51803-78-2

Port:

Rotterdam

Packaging:

bags

Price valid (until):

2025-02-13

Company Type:
Distributor
Location:
Netherlands
Qualification:
Main Products:

ethanol,ascorbic acid,acetone,Poly(ethylene) LDPE,Polypropylene,sodium carbonate

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) commonly used to reduce pain, inflammation, and fever. It is primarily used to treat conditions such as osteoarthritis, rheumatoid arthritis, and acute pain, including pain associated with dental procedures, musculoskeletal injuries, or surgery. Nimesulide works by inhibiting the enzyme cyclooxygenase (COX), which plays a role in producing prostaglandins, chemicals in the body that promote inflammation, pain, and fever.

    Common Uses:

    • Pain relief: For conditions like headache, back pain, dental pain, or menstrual cramps.
    • Anti-inflammatory: Used in conditions like osteoarthritis and other joint-related issues.
    • Fever reduction: It can help reduce fever associated with various infections.

    Dosage and Administration:

    The dosage of Nimesulide typically varies depending on the patient's age, condition, and the severity of symptoms. It is usually prescribed to be taken in tablet or oral suspension form. Always follow the doctor's recommendations or the instructions provided by the pharmacist.

    Side Effects:

    Common side effects of Nimesulide may include:

    • Nausea or upset stomach
    • Dizziness or drowsiness
    • Headache
    • Skin rash

    More serious side effects (though rare) can include liver damage, gastrointestinal bleeding, or kidney problems. Therefore, it should be used with caution, especially in individuals with liver or kidney issues, or those taking other medications that may interact with Nimesulide.

    Warnings:

    • Liver concerns: Nimesulide has been associated with liver toxicity in some cases, and its use is restricted or limited in some countries due to concerns over liver damage.
    • Gastrointestinal issues: Like other NSAIDs, Nimesulide may cause ulcers or bleeding in the stomach or intestines.
    • Kidney function: It should be used with caution in people with pre-existing kidney conditions.
    • Pregnancy and breastfeeding: Nimesulide should generally be avoided during pregnancy and breastfeeding unless specifically advised by a doctor.

    Conclusion:

    As with any medication, it is important to use Nimesulide only under the supervision of a healthcare provider to minimize risks and ensure it is appropriate for your specific condition. Always read the label and follow medical advice carefully.

     


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    Items Specifications






    Basic Info
    Product Name:

    Nimesulide

    Other Name:

    nimed;4-NITRO-2-PHENOXYMETHANE SULPHONANILIDE;CETIRIZINE DIHYDROCHLORIDE EPC(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE IMP. E (EP):(RS)-2-[2-[2-[4-[(4-CHLOROPHENYL)-PHENYLMETHYL]PIPERAZIN-1-YL]ETHOXY]ETHOXY]ACETIC ACID MM(CRM STANDARD);CETIRIZINE DIHYDROCHLORIDE MM(CRM STANDARD);4-Nitro-2-phenoxymethanesulfonamide;Nide;Nidol

    CAS No.:

    51803-78-2

    Molecular Formula:

    C13H12N2O5S

    InChIKeys:

    HYWYRSMBCFDLJT-UHFFFAOYSA-N

    Molecular Weight:

    308.31

    Exact Mass:

    308.31

    EC Number:

    257-431-4

    Color/Form:

    Light orange to Yellow to Green

    HScode:

    2935.90.9500

    Categories:

    Organic Reagents

    Characteristics
    λmax:

    391nm(H2O)(lit.)

    PSA:

    110

    XLogP3:

    2.6

    Appearance:

    Yellow Needle-Like Crystals

    Density:

    1.451±0.06 g/cm3(Predicted)

    Melting Point:

    140-146°C

    Boiling Point:

    442.0±55.0 °C(Predicted)

    Flash Point:

    221.1±31.5 °C

    Refractive Index:

    1.638

    Water Solubility:

    Soluble in water (<50 µg/ml), 1:10 DMSO:PBS (pH 7.2) (<200 µg/ml), ethanol (1 mg/ml), DMSO (15 mg/ml), DMF (15 mg/ml), chloroform, dichloromethane, acetone (freely soluble), and 1N NaOH.

    Storage Conditions:

    2-8°C

    Toxicity:

    LD50 orally in rats: 324 mg/kg (Swingle, Moore)

    PKA:

    pKa 6.56± 0.03(H2O,t =25,I=0.02)(Approximate)

    Critical Temperature & Pressure:

    2-8°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    ethanol,ascorbic acid,acetone,Poly(ethylene) LDPE,Polypropylene,sodium carbonate

    Location:

    Admiraal Banckertweg 12 2315 SR, Leiden, Zuid-Holland

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment

    Average lead Time:

    45

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2010

    Certifications:

    business

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Kazakstan

    Nimesulide

    20 MT Jan 14, 2025
    India

    Nimesulide powder BP grade

    50.00 KG Mar 11, 2024
    Post an enquiry for this product
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