Demeclocycline hydrochloride 95% lightly yellow powder CAS NO 64-73-3 DIDEU
TDS 1 Inquiries
64-73-3
Pharmaceutical Grade
95%
By Fedex door to door
Dideu
25kg/Drum
Yes
2025-02-17
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceDemeclocycline Hcl is a tetracycline antibiotic; is an antibiotic in the treatment of Lyme disease, acne, and bronchitis.
Demeclocycline hydrochloride is the hydrochloride salt of demeclocycline. A tetracycline antibiotic, it is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. It has a role as an antibacterial drug. It contains a demeclocycline.|Demeclocycline Hydrochloride is the hydrochloride salt of demeclocycline, a broad-spectrum, tetracycline derivative exhibiting antimicrobial, aquaretic and chelating activities. In bacteria, demeclocycline binds reversibly to the 30S ribosomal subunit and blocks the binding of aminoacyl-tRNA to the A-site of the mRNA-ribosome complex, resulting in the inhibition of protein synthesis and bacterial cell death. In mammals, this agent interferes with the action of antidiuretic hormone (ADH) at the level of the renal collecting tubule, resulting in aquaresis. In addition, demeclocycline, which like other tetracyclines chelates calcium in bone and exhibits a yellow fluorescence under ultraviolet (UV) light, may be used as a fluorescent bone-labeling agent in bone histomorphometry.|A TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.CertificatesBasic Info-
Product Name:
Demeclocycline hydrochloride
Other Name:2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,hydrochloride (1:1),(4S,4aS,5aS,6S,12aS)-;2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,monohydrochloride;2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,monohydrochloride,[4S-(4α,4aα,5aα,6β,12aα)]-;2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-,monohydrochloride,(4S,4aS,5aS,6S,12aS)-;7-Chloro-6-demethyltetracycline hydrochloride;7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride;Declomycin hydrochloride;Demeclocycline hydrochloride;Demethylchlorotetracycline hydrochloride;Ledermycin hydrochloride;6-Demethyl-7-chlorotetracycline hydrochloride;Declomycin;Meciclin;Detravis;Demetraciclina;Clortetrin
CAS No.:64-73-3
Molecular Formula:C21H21ClN2O8.ClH
InChIKeys:InChIKey=GVSJQNRGSCOSNJ-KBHRXELFSA-N
Molecular Weight:501.32
Exact Mass:500.075317
EC Number:200-592-2
UNII:29O079NTYT
NSC Number:756708
DSSTox ID:DTXSID0045252
NCI Thesaurus Code:C28975
HScode:29413020
Categories:
Characteristics-
PSA:
182
XLogP3:1.76720
Appearance:powder
Melting Point:>245°C (dec.)
Boiling Point:795.9°C at 760 mmHg
Flash Point:435.2ºC
Water Solubility:soluble in water.H2O: 20 mg/mL, clear, very deep greenish yellow
Storage Conditions:−20°C
Toxicity:LD50 orally in rats: 2372 mg/kg (Goldenthal)
Collision Cross Section:195.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
India
Dimethylchlrtetracycline hcl
1.00 G Jul 24, 2025 Post an enquiry for this product
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