 Home > Biochemical Engineering > Polypeptide > 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid for Sale > Cheap Price High Quality Cilengitide Powder Cas 188968-51-6 Global Warehouse

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CAS No.:

188968-51-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shang Hai

Brand:

KDG

Packaging:

1g/bottle

Sample Available:

Yes

Price valid (until):

2025-04-07

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Hubei KDG Web Science&Technology Co.,Ltd

Company Type:

Trader

Location:

China

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Main Products:

Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin

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Product Details
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Description

Product Detail

- Cilengitide, a cyclic RGD pentapeptide , is currently in clinical phase III fortreatment of glioblastomas and in phase II for several other tumors. Thisdrug is the first anti-angiogenic small molecule targeting the integrins αvβ3, αvβ5 and α5β1.

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ECHEMI Editorial Reference

Cilengitide is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50s of 4 and 79 nM, respectively.
Cilengitide is an oligopeptide.|Cilengitide has been used in trials studying the treatment of Sarcoma, Gliomas, Lymphoma, Leukemia, and Lung Cancer, among others.|Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. (NCI04)

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Basic Info

Product Name:

2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid

Other Name:

2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid;Cyclo(L-arginylglycyl-L-aspartyl-D-phenylalanyl-N-methyl-L-valyl);Cilengitide;Cilengitide(EMD121974,NSC-707544);NSC 707544;Cilengitide, >=98%;Cyclo(Arg-Gly-Asp-D-Phe-N-Me-Val);c(RGDf(NMe)V)

CAS No.:

188968-51-6

Molecular Formula:

C27H40N8O7

InChIKeys:

AMLYAMJWYAIXIA-VWNVYAMZSA-N

Molecular Weight:

588.662

Exact Mass:

588.302002

UNII:

4EDF46E4GI

DSSTox ID:

DTXSID9044035

NCI Thesaurus Code:

C1834

Categories:

Polypeptide

Characteristics

PSA:

238

XLogP3:

-2.46

Density:

1.4±0.1 g/cm3

Refractive Index:

1.643

See More 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 2-[(2S,5R,8S,11S)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin

Location:
Room H0413, Building 1, No. 58, Guanggu Avenue, East Lake New Technology Development,Wuhan

Year of Establishment:
2020
Country Product Purchase Quantity Date Posted

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Product Name	Grade / Content	Price	Supplier Name	Details
High quality 99% purity Cilengitide CAS 188968-51-6	Pharmaceutical Grade/99	$1/UNIT FOB	Shandong Xinshunyue Energy Co., Ltd.	Inquiry
Cilengitide CAS 188968-51-6 98% Purity Integrin αvβ3/αvβ5 Inhibitor for Anticancer and Angiogenesis Research kr	Reagent Grade/99	$100-130/G FOB	Jinan topfull chemical co.,ltd	Inquiry
Cilengitide (EMD 121974) hot sale high quality white raw powder 5mg	Pharmaceutical Grade/99		Jinshu Peptide Co.,Ltd	Inquiry
Cilengitide	Research and Industrial Grade/98.00		Hangzhou Go Top Peptide Biotech Co.,Ltd.	Inquiry
High Quality Cheap Price Cilengitide Powder Cas 188968-51-6	Pharmaceutical Grade/99		Eternal Wealth (China) Limited	Inquiry

Cheap Price High Quality Cilengitide Powder Cas 188968-51-6 Global Warehouse

Product Details

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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