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2-FLUOROACRYLIC ACID

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CAS No.:

430-99-9

Grade:

Pharmaceutical Grade

Packaging:

25kg/Cardboard Drum

Price valid (until):

2025-04-30

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SHANDONG LOOK CHEMICAL CO.,LTD

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

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Product Description
Seller Information

Description

Product Detail

2-Fluoroacrylic acid (CAS 430-99-9) is a fluorinated derivative of acrylic acid with unique chemical properties that make it invaluable in advanced material synthesis. This organofluorine compound features a fluorine atom at the β-position of the acrylic acid structure, significantly altering its reactivity compared to non-fluorinated analogs. The presence of fluorine enhances thermal stability while maintaining the characteristic polymerizability of acrylic acid derivatives. Industrial applications of 2-Fluoroacrylic acid span pharmaceuticals, specialty polymers, and agrochemical intermediates, with growing interest in its use for lithium-ion battery electrolytes due to its electrochemical stability.

Chemical & Physical Properties

Physical Characteristics

Molecular Formula: C₃H₃FO₂
Molecular Weight: 106.05 g/mol
Appearance: Clear colorless liquid
Boiling Point: 152-154°C (760 mmHg)

Chemical Behavior

pKa: 2.68 (25°C)
Solubility: Miscible with polar solvents
Polymerization: Forms fluorinated polyacrylates

Advanced Industrial Applications

Pharmaceutical Manufacturing

Antiviral Drug Synthesis

2-Fluoroacrylic acid serves as critical building block for neuraminidase inhibitors, enabling creation of fluorinated oseltamivir derivatives with enhanced bioavailability. The fluorine moiety improves metabolic stability of protease inhibitors by reducing hepatic clearance rates.

Targeted Drug Delivery

Functionalized 2-Fluoroacrylic acid derivatives form pH-responsive polymer carriers for tumor-specific chemotherapy. Fluorine atoms enhance MRI contrast capabilities in theranostic nanoparticles through 19F magnetic resonance imaging compatibility.

Advanced Polymer Systems

Weather-resistant Coatings

Copolymers containing 2-Fluoroacrylic acid demonstrate exceptional UV stability (95% gloss retention after 3000h QUV testing) through C-F bond protection mechanisms. Widely used in automotive clearcoats and photovoltaic module encapsulants.

Flexible Electronics

Dielectric films incorporating 2-Fluoroacrylic acid achieve low Dk values (2.3-2.7 @10GHz) with high mechanical flexibility (5000+ bend cycles at 5mm radius). Essential for 5G flexible circuit substrates and foldable display components.

Energy Storage Solutions

Lithium Battery Electrolytes

2-Fluoroacrylic acid derivatives improve LiPF6 electrolyte stability at 60°C+ operating temperatures. Fluorinated SEI layers reduce dendritic growth by 73% compared to standard carbonate-based systems.

Fuel Cell Membranes

Sulfonated copolymers using 2-Fluoroacrylic acid maintain proton conductivity >0.1 S/cm at 120°C with 40% lower methanol crossover than Nafion® membranes. Critical for high-temperature PEM fuel cell applications.

Synthesis Methods

Fluorination of propiolic acid derivatives
Catalytic halogen exchange reactions
Electrochemical fluorination processes

Technical Specifications

Parameter	Specification
Purity	≥99.5% (HPLC)
Fluorine Content	17.9-18.2%

Items	Specifications

Basic Info

Product Name:

2-FLUOROACRYLICACID

Other Name:

1g,2g,5g;2-FLUOROACRYLICACID;2-FLUOROPROPENOICACID;alpha-Fluoroacrylicacid;2-FLUOROACRYLICACID97%;2-Fluoroprop-2-enoicacid;2-Propenoicacid,2-fluoro-

CAS No.:

430-99-9

Molecular Formula:

C3H3FO2

InChIKeys:

TYCFGHUTYSLISP-UHFFFAOYSA-N

Molecular Weight:

90.05

Exact Mass:

90.011711

UNII:

BEP1A791CI

HScode:

2916190090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

37.3

XLogP3:

0.7

Density:

1.2±0.1 g/cm3

Melting Point:

51.5ºC

Boiling Point:

181.3°C at 760 mmHg

Flash Point:

63.5±19.0 °C

Refractive Index:

1.388

See More 2-FLUOROACRYLICACID Properties 

Hazard Identification

Classification of the substance or mixture

Skin corrosion, Sub-category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H314 Causes severe skin burns and eye damage
Prevention	P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 Wash contaminated clothing before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P316 Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 2-FLUOROACRYLICACID Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

Location:
hisense intelligence valley,no 2116,of phoenix road

Payment Terms:
TT against copy of documents,D/P,L/C

Average lead Time:
7

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2017

SHANDONG LOOK CHEMICAL CO.LTD, a new chemical enterprise in researching, manufacturing and supplying of chemicals located in beautiful “Spring City”-Jinan.Our company mainly working on the researching new-born APIs, intermediate ( especially Carbohydrate derivatives series). Meanwhile, we made huge breakthrough in industries of food, feed additives, cosmetics ,dye and industrial chemicals. Our company enjoyed great reputation both domestic and abroad under the belief of “Integrity management,Quality controlling and Customer orientation”. Web : www.chinalookchemical.com

We had been cooperated with NingXia University and Shandong University on more than ten projects for years and which had been in mass production on the market. We now have more than 80 people in our team and built research center in Jinan and Ningxia. Our manufacturing site allocated in chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly complying with ISO9001 and ISO 2000 standard in manufacturing process, our lab and workshop tightly in accordance with GMP standard.Our products best selling in Europe, South and North America,Asia pacific area and Africa. We sincerely welcome new and regular customers around the world visit us for business negotiation.
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