High Purity α-Naphthoflavone (CAS 604-59-1) Supplier

As a leading chemical manufacturer with over a decade of experience, we specialize in producing premium-grade α-Naphthoflavone (CAS 604-59-1), a potent aryl hydrocarbon receptor antagonist with extensive applications in biochemical research. This synthetic flavonoid derivative demonstrates remarkable biological activity in modulating cytochrome P450 enzymes and estrogen receptor interactions. Our α-Naphthoflavone undergoes rigorous HPLC purification to achieve ≥98% purity, validated through comprehensive NMR and mass spectrometry analysis. Available in crystalline powder form with batch-specific COA, this compound meets strict research-grade standards for pharmacology and molecular biology studies.

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Chemical Specifications

• Molecular Formula: C₁₉H₁₄O₂
• Molecular Weight: 274.32 g/mol
• Appearance: Yellow crystalline powder
• Solubility: DMSO >50 mg/mL
• Purity: ≥98% (HPLC)
• Storage: -20°C, protected from light

Why Choose Our α-Naphthoflavone?

• High Purity: Rigorous purification processes ensure ≥98% purity, validated by advanced analytical techniques.
• Batch Consistency: Each batch comes with a Certificate of Analysis (COA) for traceability and quality assurance.
• Global Compliance: Meets REACH, ISO, and GMP standards for international distribution.
• Custom Packaging: Available in various quantities, from milligrams to kilograms, with customized packaging options.
• Technical Support: Our team of experts provides comprehensive technical documentation and application guidance.

Research Applications

α-Naphthoflavone is widely used in biochemical and pharmacological research due to its unique properties:

• CYP1A Enzyme Studies: As a selective inhibitor, it helps elucidate the role of cytochrome P450 enzymes in drug metabolism.
• Estrogen Receptor Research: Its ability to modulate estrogen receptor activity makes it valuable in hormone-related studies.
• Xenobiotic Metabolism: Used to investigate the metabolism of foreign compounds in biological systems.
• Cancer Research: Potential applications in studying the role of aryl hydrocarbon receptors in tumorigenesis.

Quality Control

Our α-Naphthoflavone undergoes a multi-step quality control process to ensure the highest standards:

1. Raw Material Screening: Sourcing from certified suppliers with strict quality criteria.
2. Purification: Advanced HPLC and crystallization techniques to achieve high purity.
3. Analytical Testing: Comprehensive characterization using NMR, MS, and FTIR.
4. Batch Documentation: Detailed COA provided with each shipment.

Safety & Handling

Proper handling and storage are essential for maintaining the integrity of α-Naphthoflavone:

• Store at -20°C in a tightly sealed container, protected from light.
• Use appropriate personal protective equipment (PPE), including gloves and lab coats.
• Avoid inhalation or direct contact with skin and eyes.
• Refer to the Safety Data Sheet (SDS) for detailed handling instructions.