GMP Factory Made Cheap Price Pramoxine hydrochloride CAS 637-58-1
GMP FDA
637-58-1
Pharmaceutical Grade
99%
SHANGHAI
KDG
1KG/BAG
Yes
2025-04-11
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferencePramocaine hydrochloride is a topical anesthetic, and used as an antipruritic.
Pramoxine hydrochloride is an aromatic ether.|Pramocaine Hydrochloride is the hydrochloride salt form of pramoxine, a morpholine derivative with local anesthetic property. Pramocaine hydrochloride decreases the permeability of the neuronal membrane to sodium ions by reversibly binding to and inhibiting voltage-gated sodium channels. This results in stabilization of the membrane and, thereby inhibiting the ionic fluxes required for membrane depolarization, hence resulting in the failure to initiate a propagated action potential and subsequent conduction blockade.CertificatesBasic Info-
Product Name:
Pramoxine hydrochloride
Other Name:Morpholine,4-[3-(4-butoxyphenoxy)propyl]-,hydrochloride (1:1);Morpholine,4-[3-(p-butoxyphenoxy)propyl]-,hydrochloride;Pramoxine hydrochloride;Morpholine,4-[3-(4-butoxyphenoxy)propyl]-,hydrochloride;4-[3-(p-Butoxyphenoxy)propyl]morpholine hydrochloride;Tronothane hydrochloride;Pramocaine hydrochloride;Proctofoam;Tronothan;Tronothane;Tronolaine;Pramacort
CAS No.:637-58-1
Molecular Formula:C17H27NO3.ClH
InChIKeys:InChIKey=SYCBXBCPLUFJID-UHFFFAOYSA-N
Molecular Weight:329.86
Exact Mass:329.175781
EC Number:211-293-1
UNII:88AYB867L5
NSC Number:757847|25573
DSSTox ID:DTXSID2047777
NCI Thesaurus Code:C47682
Color/Form:Crystals
HScode:2934999090
Categories:
Characteristics-
PSA:
30.93000
XLogP3:3.70650
Appearance:White or off white crystalline powder
Melting Point:181-183 °C
Boiling Point:427ºC at 760 mmHg
Flash Point:123.5ºC
Water Solubility:>49.5 [ug/mL]
Storage Conditions:Preparations containing pramoxine hydrochloride cream or ointment should be stored in tight containers at at temperatures of 15-30 deg C. Pramoxine hydrochloride aerosol preparations should be stored at room temperature. Because the contents are under pressure, the aerosol container should not be punctured, used or stored near hear or an open flame, exposed to temperatures greater than 49 deg C, ... .
Toxicity:LD50 i.v. in mice: 79.5 ±2.7 mg/kg (Schmidt); LD50 in mice (mg/kg): 300 i.p., 750 s.c. (Monash, Gibbs)
Collision Cross Section:178.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Preparations containing pramoxine hydrochloride cream or ointment should be stored in tight containers at at temperatures of 15-30 deg C. Pramoxine hydrochloride aerosol preparations should be stored at room temperature. Because the contents are under pressure, the aerosol container should not be punctured, used or stored near hear or an open flame, exposed to temperatures greater than 49 deg C, .
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Seller Information
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Business Type:
Trader
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Main Products:
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin
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Location:
Room H0413, Building 1, No. 58, Guanggu Avenue, East Lake New Technology Development,Wuhan
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Year of Establishment:
2020
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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