Hot Selling Chemicals Raw Peptide CAS 859216-15-2 HKPao
22 Inquiries
859216-15-2
Industrial Grade
99%
Shanghai
Shanghai Jinbei
10vials/box
Yes
2025-05-14
pharmaceutical,Cosmetic,Pregabalin,2,5-Dimethoxybenzaldehyde,Diphenylacetonitrile,2-Dimethylaminoisopropyl chloride hydrochloride,Tildenafil
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial Reference
Adipotide is a synthetic chimeric peptidomimetic composed of a prohibitin-targeting peptide and a pro-apoptotic peptide sequence. Its defined structure, commonly represented as CKGGRAKDC-GG-D(KLAKLAK)₂, combines a vascular-targeting domain with a pro-apoptotic domain. As a specialized peptide research and pharmaceutical raw material, Adipotide is suitable for biochemical research, analytical studies, and pharmaceutical development.
Basic Info-
Product Name:
HKPao
Other Name:D-Lysine, L-cysteinyl-L-lysylglycylglycyl-L-arginyl-L-alanyl-L-lysyl-L-α-aspartyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-;Adipotide Powder;Weight Loss Peptides Adipotide Adipotide Ftpp;HKPao;Adipotide (FTPP) 5mg 10mg;Prohibitin-targeting peptide 1
CAS No.:859216-15-2
Molecular Formula:C111H206N36O28S2
InChIKeys:GZESIPHLGJDZRG-XRIURATCNA-N
Molecular Weight:2557.21
EC Number:200-001-8
Categories:
Characteristics-
Density:
1.40±0.1 g/cm3(Predicted)
Research-
Class:
Chimeric peptidomimetic (fat-targeting vascular disruptor)
Status:Research compound — Not FDA approved, clinical development discontinued
Mechanism:A synthetic chimeric peptide composed of a fat-vascular-targeting cyclic peptide (CKGGRAKDC) linked via a GG spacer to a pro-apoptotic peptide (KLAKLAK)2. Adipotide selectively binds prohibitin in the vasculature of white adipose tissue, then delivers the pro-apoptotic domain to induce vascular disruption, causing fat tissue death. In primate studies (2011), it produced significant weight loss (~11%) but also caused renal toxicity, leading to development discontinuation.
Activity note:Adipotide is not a receptor agonist. It functions as a targeted vascular disruptor. Functional activity is measured by tissue-specific apoptosis, not traditional EC50.
Source:PubChem: Adipotide (CID 163360068); Kolonin MG, et al. Sci Transl Med. 2004;6(148):148ra16.DOI
References-
PubChem:Literature:
Sci Transl Med: Kolonin MG, et al. (2004) — Adipotide mechanism; ChemicalBook: Adipotide (CAS 859216-15-2)
Disclaimer:Adipotide is NOT FDA-approved or EMA-approved. It is a research compound only. Clinical development was discontinued due to renal toxicity observed in primate studies. This listing is for industrial and laboratory research use only. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
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Seller Information
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Business Type:
Trader
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Main Products:
pharmaceutical,Cosmetic,Pregabalin,2,5-Dimethoxybenzaldehyde,Diphenylacetonitrile,2-Dimethylaminoisopropyl chloride hydrochloride,Tildenafil
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Location:
shanghai fengqianqu
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Inquiry History22 Inquiries
Country Product Purchase Quantity Date Posted
United States
Adipotide
10 MG Jun 6, 2025
United States
adipotide
10 May 30, 2025
United States
Adipotide
2 BOU Nov 26, 2024
Germany
Adipotide
100 Nov 6, 2024
United States
Adipotide
1 MT Sep 18, 2026
Mexico
adipotide
5 G Sep 8, 2025
United States
adipotide
10 MG Aug 21, 2025
United States
adipotide
15 MG Jun 15, 2025
Germany
Adipotide FTPP
200 MG Oct 18, 2024
United States
Adipotide 10mg
3 MT Sep 27, 2026
United States
adipotide
1 KG Feb 24, 2026
Philippines
Adipotide
10 PCS Oct 20, 2025
United States
ADIPOTIDE
100 MG Jul 21, 2025
Thailand
adipotide
100 Apr 23, 2025
United States
Adipotide
10 G Apr 18, 2025
United States
Adipotide
5 G Apr 12, 2025
United States
Adipotide
5 MG Jan 9, 2025
United States
99% Purity Weight Loss Peptide Adipotide for Slimdown
57 KG Nov 30, 2024
United States
Adipotide
500 MG Nov 20, 2024
United States
Adipotide
10 G Sep 25, 2024 Post an enquiry for this product
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