Wholesales Nicotinamide riboside chloride with Best Quality

I. Basic Information

• Chemical Name: Nicotinamide Riboside (abbreviated as NR)
• Molecular Formula: C₁₁H₁₅N₂O₅Cl (chloride form)
• CAS Number: 23111-00-4
• Properties: White crystalline powder, highly water-soluble, chemically stable, and generally recognized as safe (GRAS).

II. Core Functions

1. NAD⁺ Precursor:
   • NR serves as a direct precursor to nicotinamide adenine dinucleotide (NAD⁺), participating in critical physiological processes such as cellular energy metabolism, DNA repair, and circadian rhythm regulation.
   • Supplementation with NR significantly elevates NAD⁺ levels in tissues, activating sirtuins to delay aging and enhance metabolic function.
2. Metabolic Regulation:
   • Promotes the conversion of carbohydrates, fats, and proteins into energy, alleviating fatigue.
   • Enhances insulin sensitivity and ameliorates metabolic abnormalities induced by high-fat diets.
3. Neuroprotection:
   • In Alzheimer’s disease models, NR penetrates the blood-brain barrier, stimulating NAD⁺ synthesis in the brain and mitigating neural damage.
4. Mitochondrial Health:
   • Improves mitochondrial function, induces mitochondrial biogenesis, and boosts cellular energy production.

III. Applications

1. Biopharmaceuticals:
   • Anti-Aging Research: By elevating NAD⁺ levels, NR delays cellular aging and alleviates age-related cognitive and metabolic disorders.
   • Neurodegenerative Diseases: NR’s neuroprotective effects offer potential therapeutic avenues for Alzheimer’s and Parkinson’s diseases.
   • Metabolic Disorders: Used as an adjuvant therapy for obesity, diabetes, and other metabolic syndromes.
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3. Nutritional Supplements:
   • Energy Enhancement: Reduces fatigue and enhances athletic performance.
   • Immune Support: Restores antiviral PARP function and strengthens innate immunity.
   • Cardiovascular Health: Regulates blood lipids and lowers hypertension risk.
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   • Cosmetics:
4. • Antioxidant and Anti-Aging: Scavenges free radicals, improves skin elasticity, and fades age spots.
   • Moisturization and Repair: Strengthens the skin barrier and promotes collagen synthesis.