Supply High Quality CAS 116122-36-2 Breviscapin

Overview of Breviscapin

Breviscapin, also known as Scutellarin, is a flavonoid compound extracted from plants such as Erigeron breviscapus. Its chemical name is 7-[(β-D-glucuronosyl)oxy]-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, with a CAS number of 116122-36-2, a molecular formula of C₂₁H₁₈O₁₂, and a molecular weight of approximately 462.36. Breviscapin typically appears as a brownish-yellow powder and exhibits a wide range of pharmacological activities.

Applications of Breviscapin

1. Treatment of Cardiovascular Diseases :
   • Breviscapin possesses cardiovascular pharmacological activities such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation, and preventing thrombus formation.
   • It has been studied for the treatment of cardiovascular diseases, including cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease, and angina pectoris.
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2. Neuroprotection :
   • Breviscapin can downregulate the STAT3/Girdin/Akt signaling pathway in HCC cells and inhibit the RANKL-mediated MAPK and NF-κB signaling pathways in osteoclasts, thereby exerting neuroprotective effects.
   • This makes Breviscapin potentially valuable in the treatment of neurodegenerative diseases, brain injuries, and other neurological disorders.
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3. Anti-inflammatory and Antioxidant Effects:
   • Breviscapin exhibits antioxidant and anti-inflammatory activities, capable of scavenging free radicals and mitigating tissue damage caused by oxidative stress and inflammatory responses.
   • This positions it for potential applications in anti-inflammatory drugs and antioxidant health supplements.
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4. Antitumor Research:
   • Breviscapin demonstrates certain antitumor activities, capable of inhibiting the proliferation and metastasis of tumor cells.
   • Currently, it is being investigated as a potential antitumor drug or adjuvant therapy.
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5. Scientific Research and Drug Development:
   • As a natural product, Breviscapin holds significant importance in drug research and development. It is often used as an active ingredient in cellular and biological experiments to study drug mechanisms of action and screen for new drugs.
   • Additionally, Breviscapin is utilized in the preparation of various pharmaceutical formulations, such as injections, tablets, and capsules, to meet the diverse therapeutic needs of patients.