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High quality Bortezomib 99%

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

179324-69-7

Grade:

Industrial Grade

Content:

99%

Port:

China

Brand:

JY

Packaging:

25kg/drum

Price valid (until):

2025-06-14

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Peptides

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Bortezomib, a modified dipeptidyl boronic acid, is a therapeutic proteasome inhibitors used for the treatment of cancers. It is indicated for the treatment of relapsed multiple myeloma and mantle cell lymphoma. It is capable of inhibiting the mammalian 26S proteasome, which is important in regulating the intracellular concentration of specific proteins to maintain homeostasis within cells. The disruption of 26S proteasome function disrupts normal cellular homeostasis, leading to cytotoxic effect on various kinds of cancer cells.

    Product Name: Bortezomib
    Synonyms: Bortezomib for Injection;3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butylboronic acid;Bortezomib (Intermediate in China ONLY);Boronic acid, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]bu;MG-341 PS-341;BortezoMib Base;BortezoMib-D8;bortezoMib(other)
    CAS: 179324-69-7
    MF: C19H25BN4O4
    MW: 384.24
    EINECS: 605-854-3
    Product Categories: ProteasomeInhibitors;Apis;Boron Derivatives;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Pepetides;Inhibitor;Final material;API;peptides
    Mol File: 179324-69-7.mol
    Melting point  122-124°C
    density  1.214
    RTECS  ED7771666
    storage temp.  Hygroscopic, -20°C Freezer, Under Inert Atmosphere
    solubility  Soluble in chloroform, dimethyl sulfoxide, ethanol and methanol.
    pka 9.66±0.43(Predicted)
    Stability: Hygroscopic and Moisture Sensitive
    CAS DataBase Reference 179324-69-7(CAS DataBase Reference)
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      Company introduction  


    Our company, Jianyan E-commerce Trading House in Yiwu City, is an innovative company mainly engaged in the research and development, production and sales of pharmaceutical intermediates and fine chemicals. The products are mainly used in the fields of medicine, health products, cosmetics, pesticides and electronic chemistry.
      We have a research and development centre and a production base. The R&D centre has advanced organic synthesis and analytical testing equipment. At the production base, we have large reaction vessels, including various specifications of stainless steel reaction vessels and enamel reaction vessels, capable of high-pressure,high-temperature and low-temperature reactions, with production capacities ranging from kilograms to tonnes. The company has established a comprehensive marketing network and its products are exported to countries and regions such as the United States, South Korea, Japan, India and Europe.

    Our advantage
    1. Own your own chemical plant
    2. Rich professional production experience
    3. Sample free and in stock, delivery
    4. Price, quality and service, we care about all your concerns
    5. Timely reply Keep in touch to save your time
    6. Easy customs clearance, we have all these controlsAll very good
    7. Dedicated researchers customize it for you.
    Customer Trade Show

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    FAQ
    1. I did not find what I was looking for. Do you provide specific pack sizes or different packaging?

    We are all about finding or creating the right solution for you. Our team is ready to work with you to meet your specific needs, even for small quantities. Please contact us.

    2. Can I buy samples?

    Please feel free to contact us.

    3.What is your lead time?

    It depends on the proudct and order quantity. Please contact us.

    4. How can I get a price?

    After we get your inquiry, we usually quote within 24 hours.

    5. How to confirm the quality before placing the order?

    You can get free samples for some products, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.

    7. Do you provide COA?

    Yes. We'll provide certificate of analysis before shipment

    Basic Info
    Product Name:

    Bortezomib

    Other Name:

    Boronic acid,B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-;Boronic acid,[3-methyl-1-[[1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-,[S-(R*,S*)]-;Boronic acid,[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]-;B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid;PS 341;PS 341 (pharmaceutical);MG 341;LDP 341;Bortezomib;MLN 341;Velcade;NSC 681239;DPBA;Radiciol;PS 314;Brotezamide;197730-97-5

    CAS No.:

    179324-69-7

    Molecular Formula:

    C19H25BN4O4

    InChIKeys:

    InChIKey=GXJABQQUPOEUTA-RDJZCZTQSA-N

    Molecular Weight:

    384.23700

    Exact Mass:

    384.24

    EC Number:

    605-854-3

    UNII:

    69G8BD63PP

    NSC Number:

    681239

    DSSTox ID:

    DTXSID3040980

    NCI Thesaurus Code:

    C1851

    Color/Form:

    Powder

    ATC Code:

    L01XG01|L01XX32|L - Antineoplastic and immunomodulating agents

    HScode:

    2934999090

    Characteristics
    PSA:

    124.44000

    XLogP3:

    log Kow = 2.0 (est)

    Density:

    1.214

    Melting Point:

    122-124ºC

    Refractive Index:

    1.564

    Water Solubility:

    The solubility of bortezomib, as the monomeric boronic acid, is 3.3 to 3.8 mg/mL in a pH range of 2 to 6.5.

    Storage Conditions:

    Unopened vials may be stored at controlled room temperature 25 deg C (77 deg F); excursions permitted from 15 to 30 deg C (59 to 86 deg F). Retain in original package to protect from light.

    Vapor Pressure:

    5.1X10-20 mm Hg at 25 deg C (est)

    Henrys Law Constant:

    Henry's Law constant = 3.4X10-22 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    Hydroxyl radical reaction rate constant = 2.6X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 1, Oral

    Skin irritation, Category 2

    Eye irritation, Category 2

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides

    Location:

    Room 5003, 5th Floor, Yau Lee Centre, 45 Yuen Yuen Road, Kwun Tong, Hong Kong

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2024

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Brazil

    Bortezomibe

    1.00 KG Mar 28, 2025
    India

    Bortezomib  

    1.00 KG Jul 12, 2024
    Post an enquiry for this product
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