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API Neboglamine

22 Inquiries

Unit Price: Get Latest Price
CAS No.:

163000-63-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-07-12

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Neboglamine

    CAS number

    163000-63-3

    Synonym

    CR-2249; XY-2401; CR2249; XY2401; CR 2249; XY 2401; Neboglamine;

    Description

    Neboglamine is a glycine NMDA-associated agonist potentially for the treatment of schizophrenia.

    Structure

    Shop API Neboglamine-Detailed Image 1

    Molecular Formula

    C13H24N2O3

    Molecular Weight

    256.340

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 – 4 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Neboglamine More Info

    Neboglamine is a functional modulator of the glycine site on the N - methyl - D - aspartate (NMDA) receptor.

    Basic Information

    Chemical Name: (4S)-4 - amino - 5 - ((4,4 - dimethylcyclohexyl) amino) - 5 - oxopentanoic acid.

    Molecular Formula: C₁₃H₂₄N₂O₃.

    Molecular Weight: 256.34126 g/mol.

    Other Names: It was formerly known as nebostinel. Developmental code names include CR - 2249 and XY - 2401.

    Pharmacological Properties

    Target: It is a positive allosteric modulator of the glycine site of the NMDA receptor. The dysfunction of the NMDA receptor is associated with negative and cognitive symptoms in schizophrenia, so neboglamine may have a regulatory effect on these symptoms.

    Experimental Effects: In rat experiments, neboglamine, like haloperidol and clozapine, significantly increased the number of Fos - like immunoreactivity - positive cells in the prefrontal cortex, nucleus accumbens, and lateral septal nucleus, which is beneficial for promoting neuronal growth and regulating related brain functions. It also restored NMDA - mediated neurotransmitter release in frontal cortex punches exposed to the NMDA antagonist phencyclidine (PCP), indicating that it can regulate the function of the NMDA receptor and maintain the normal transmission of nerve signals.

    Clinical Research

    Treatment of Schizophrenia: Rottapharm is conducting Phase II clinical trials on neboglamine for the treatment of schizophrenia. It is expected to become a new treatment option for schizophrenia by regulating the function of the NMDA receptor and improving the negative and cognitive symptoms of patients.

    Treatment of Cocaine Addiction: Neboglamine is also in Phase II clinical trials for the treatment of cocaine abuse. It may help patients reduce their dependence on cocaine by regulating the central nervous system.

    Other Properties

    Nootropic - like Effects: Some studies suggest that neboglamine has cognitive - enhancing properties. It can enhance neurotransmitter activity in the brain, improve communication between neurons and synaptic plasticity, thereby improving learning ability, mental clarity, and overall cognitive performance. In addition, it also has neuroprotective properties, which can support brain health and reduce the risk of age - related cognitive decline.

    Shop API Neboglamine-Detailed Image 2

    Basic Info
    Product Name:

    (4S)-4-Amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxopentanoic acid

    Other Name:

    Pentanoic acid,4-amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxo-,(4S)-;Pentanoic acid,4-amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxo-,(S)-;(4S)-4-Amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxopentanoic acid;CR 2249;Nebostinel;Neboglamine

    CAS No.:

    163000-63-3

    Molecular Formula:

    C13H24N2O3

    InChIKeys:

    InChIKey=VCRGLZYPNNAVRP-JTQLQIEISA-N

    Molecular Weight:

    256.34100

    Exact Mass:

    256.34

    UNII:

    12EA34U5B8

    DSSTox ID:

    DTXSID2045787

    Categories:

    Characteristics
    PSA:

    95.91000

    XLogP3:

    2.80410

    Density:

    1.11g/cm3

    Boiling Point:

    477.1ºC at 760mmHg

    Flash Point:

    242.4ºC

    Refractive Index:

    1.515

    Vapor Pressure:

    2.03E-10mmHg at 25°C

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    22 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Neboglamine API

    100 G Dec 12, 2025
    Colombia

    Neboglamine

    5 MG Jun 12, 2025
    United States

    Neboglamine

    1 KG Aug 23, 2024
    United States

    neboglamine

    100 G Apr 27, 2026
    United States

    neboglamine

    100 G Apr 7, 2026
    United States

    Neboglamine

    150 G Feb 22, 2026
    United States

    Neboglamine

    10000 MG Jul 21, 2025
    Netherlands

    Neboglamine

    1 KG Sep 13, 2024
    Germany

    Neboglamine

    10 G May 18, 2024
    United States

    Neboglamine

    1 KG May 3, 2026
    Canada

    Neboglamine

    10 G Mar 14, 2026
    Hungary

    Neboglamine

    5 G Nov 12, 2025
    Canada

    Neboglamine

    10 G Dec 5, 2023
    United States

    Neboglamine/CR2249/CR 2249/XY-2401/XY 2401/XY2401/Neboglamine/CR-2249

    2 G Oct 4, 2023
    United States

    Nebostinel

    1 KG Sep 14, 2023
    United States

    Neboglamine

    100 G Mar 16, 2026
    Canada

    nebosintel

    1 KG Mar 16, 2026
    Germany

    Neboglamine

    1.5 G Feb 28, 2026
    United States

    Neboglamine

    10 G Oct 20, 2024
    Netherlands

    neboglamine

    1 KG Sep 19, 2024
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