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High Quality Inhibitors Pure 98% HPLC CS-1013 OTX015 OXT-015 CAS 202590-98-5

Name: High Quality Inhibitors Pure 98% HPLC CS-1013 OTX015 OXT-015 CAS 202590-98-5
Brand: HORLDEN
SKU: pr2506201092
Price: 320 USD
Availability: InStock

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CAS No.:

202590-98-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

HORLDEN

Packaging:

1g/bottle

Price valid (until):

2026-07-01

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Xi'an Horlden Bio-Tech Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

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Product Description
Seller Information

Description

Shop High quality Nootropics Selank Raw Powder Selank Peptide 10mg Vials CAS 129954-34-3-Detailed Image 1

Shop High quality Nootropics Selank Raw Powder Selank Peptide 10mg Vials CAS 129954-34-3-Detailed Image 2

Product Name	OXT-015
CAS NO.	202590-98-5
Purity	99%
Molecular formula	C25H22ClN5O2S
MOQ	1 g

OTX015 inhibits the binding of BRD2, BRD3, and BRD4 to AcH4 with IC50 ranging from 92 to 112 nM, and inhibits the growth of various human cancer cell lines with GI50 ranging from 60 to 200 nM. OTX015 leads to rapid downregulation of c-MYC expression and exhibits synergistic antiproliferative effects in combination with ALK inhibitors in ALKposALCL cell lines.

OTX015 (oral) significantly inhibits the growth of Ty82 BRD-NUT midline carcinoma tumors in nude mice by 79% at 100 mg/kg qd and 61% at 10 mg/kg.

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You can ask us for quotation and product information via Email, Phone, WhatsApp and other channels.

Email: rock@horlden.com
WhatsApp/ Signal: +86 18829283179

Shop High quality Nootropics Selank Raw Powder Selank Peptide 10mg Vials CAS 129954-34-3-Detailed Image 4

1.What's your payment terms?

Standard terms: T/T in advance. Also L/C at sight is acceptable for large amount.

2.What's your shipping time?

We have bulk in stock, which means we can ship it to you immediately.

3.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

4.How do you ship the order normally?

For large qty order,ship the goods by sea. For small qty order, by air or express. We supply optional express for you, including DHL, FEDEX,UPS,TXT,EMS,and so on.

5.What's your loading port?

Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou

ECHEMI Editorial Reference

Birabresib (OTX-015) is a potent bromodomain (BRD2/3/4) inhibitor with IC50s ranging from 92 to 112 nM.
Birabresib is under investigation in clinical trial NCT02698176 (A Dose Exploration Study With MK-8628 in Participants With Selected Advanced Solid Tumors (MK-8628-006)).|Birabresib is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4 with potential antineoplastic activity. Upon administration, birabresib binds to the acetylated lysine recognition motifs on the bromodomain of BET proteins, thereby preventing the interaction between the BET proteins and acetylated histone peptides. This disrupts chromatin remodeling and gene expression. Prevention of the expression of certain growth-promoting genes, including c-Myc-dependent target genes, may lead to an inhibition of tumor cell growth. Characterized by a tandem repeat of bromodomain at the N-terminus, the BET proteins BRD2, BRD3, BRD4 are transcriptional regulators that play an important role in cellular growth.

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Basic Info

Product Name:

(6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide

Other Name:

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide,4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-,(6S)-;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide,4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-,(S)-;(6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide;OTX 015;MK 8628;Birabresib;(-)-OTX 015;(S)-2-(4-(4-Chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]-triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetaMide;OXT 015

CAS No.:

202590-98-5

Molecular Formula:

C25H22ClN5O2S

InChIKeys:

InChIKey=GNMUEVRJHCWKTO-FQEVSTJZSA-N

Molecular Weight:

491.99248

Exact Mass:

491.99

UNII:

X40LKS49S3

NCI Thesaurus Code:

C103298

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

121

XLogP3:

4.5

Density:

1.45±0.1 g/cm3

Refractive Index:

1.730

Water Solubility:

H2O: Practically insoluble (0.015 g/L) (25 ºC)

See More (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More (6S)-4-(4-Chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Chemical,Intermediate,5-amino-1mq,SLU-PP332,Tirzepatide,Peptide

Location:
9th Floor, Room 923, Building 3, Shiyuan Daguan, Xingtai 1st Street, Chanba Ecological District, Xi'an City, Shaanxi Province

Payment Terms:
100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
11-50

Year of Establishment:
2015

Xi'an Horlden Bio-Tech Co., Ltd is committed to promoting health application products such as chemical daily necessities, APIs, pharmaceutical intermediates and Cosmetic raw materials.

We have established friendly business relationships with hundreds of customers from over 50 countries and regions. Our team is committed to providing customers with the highest quality products at reasonable prices and satisfactory service. For many years, our company has won the trust and favor of our customers with high-quality products, first-class services, and competitive prices.

We will create the highest quality and most stable supply channel for customers, adhering to the spirit of serving customers, relying on strong funds and good cooperation reputation in the industry, to provide customers with higher quality products and services. At the same time, we are willing to strengthen exchanges and sincere cooperation with domestic and foreign merchants to create a better future together. It is your best supplier.

Welcome to Xi'an Horlden Bio-Tech Co., Ltd!
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Product Name	Grade / Content	Price	Supplier Name	Details
OTX-015	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry

High Quality Inhibitors Pure 98% HPLC CS-1013 OTX015 OXT-015 CAS 202590-98-5

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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