Monobenzone CAS 103-16-2 White Crystal Powder USP Standard 99% Assay

More Info

Monobenzone is a topical depigmenting agent used to treat hyperpigmentation, such as various pigmentation spots, age spots, melanoma, etc., with significant effects. It can decompose melanin in the skin, prevent the production of melanin in the skin, restore healthy color to the skin without damaging melanocytes, and has low toxicity. It is usually made into ointment.

Pharmacodynamics

The topical application of monobenzone in animals increases the excretion of melanin from melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.

The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes. Therefore, monobenzone is used as a topical medicine to permanently depigment normal skin surrounding vitiliginous lesions only in patients with disseminated (greater than 50 percent of body surface area) idiopathic vitiligo. Monobenzone is also being considered for the treatment of melanoma .

Applications

Vitiligo Depigmentation:

Monobenzone is FDA-approved for depigmenting normal skin in cases of extensive vitiligo (affecting over 50% of the body).

Side Effects

Monobenzone can cause skin irritation, itching, and increased sensitivity to sunlight.

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We can send you a samll free sample, and you only need to pay for the shipping cost.

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