retaglutide ; weight loss;e;white powder;99.9%purity;Good Feedback Retatrutide weight loss 10/12/15mg

Product Information

Retatrutide i s an active compound released by Eli Lilly in June 2023. It is a triple (GLP-1/GIP/Gcg) agonist based on the GLP/GI dual receptor agonist Tirzepatide through a hybrid glucagon (GlucagonGcg) related structure, and is a drug for the treatment of obesity and type 2 diabetes. This active compound can activate receptor agonists in our body, which helps control blood sugar and weight loss management .

Retatrutide, LY3437943

CAS: 2381089-83-2

Molecular Formula: C221H342N46O68

Molecular Weight: 4731.33

Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Product Description

Product pictures

📝 How does retatrutide work?

Retatrutide works as a powerful triple-agonist, meaning it works on three key hormone receptors:

• The human glucagon receptor (GCGR)
• The glucose-dependent polypeptide receptor (GIP receptor)
• The glucagon-like peptide-1 receptor (GLP-1)

This unique receptor profile allows retatrutide to effectively:

• Regulate appetite, feelings of fullness, and gastric emptying
• Regulate metabolism
• Regulate blood sugar levels

The activation of the GIP, GLP-1, and GCG receptors simultaneously by retatrutide leads to better weight reduction and cardiometabolic benefits compared to targeting a single receptor. GIP is involved in glucose and lipid metabolism, GLP-1 regulates insulin secretion and appetite, and GCG plays a role in fat breakdown for energy use.

Clinical trials show that retatrutide could be the most powerful drug to be developed for the treatment of obesity. A trial published in the New England Journal of Medicine revealed that retatrutide helped patients achieve significant body weight loss. The weight-loss results at 48-weeks with the 12 mg (higher dose) retatrutide group achieved a mean weight reduction of -24.2%, while the placebo group only saw a -2.1% change.

Control Blood Sugar

Weight Loss

Indications and Efficacy:

1.  Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.

2.Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

3.Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

4. Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.

🌡️ Storing retatrutide: Refrigeration and room temperature

To ensure the efficacy and safety of retatrutide, proper storage is crucial. The storage requirements for retatrutide depend on whether the medication is in use or not.

To ensure the safety and effectiveness of retatrutide, it is crucial to keep the following considerations in mind:

• Avoid freezing: Retatrutide should never be frozen. If a pen has been frozen, it should be discarded, and a new pen should be used
• Check for damage: Before using a retatrutide pen, it is essential to inspect it carefully. If the pen is damaged, it should not be used, and a new pen should be obtained.
• Proper labelling: When storing retatrutide pens, ensure that they are properly labelled to avoid confusion with other medications or products
• Keep out of reach: Retatrutide pens should be stored out of the reach of children to prevent accidental ingestion or misuse.