High quality pruity 99% the product ofTezacaftorCAS1152311-62-0gh quality
1152311-62-0
Industrial Grade
99%
any port of china
Dideu
25kg/bag
2025-08-29
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceVX-661 is a second F508del CFTR corrector and help CFTR protein reach the cell surface.
Tezacaftor is a drug of the cystic fibrosis transmembrane conductance regulator (CFTR) potentiator class. It was developed by Vertex Pharmaceuticals and FDA approved in combination with [ivacaftor] to manage cystic fibrosis. This drug was approved by the FDA on February 12, 2018. Cystic Fibrosis is an autosomal recessive disorder caused by one of several different mutations in the gene for the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, an ion channel involved in the transport of chloride and sodium ions across cell membranes. CFTR is active in epithelial cells of organs such as of the lungs, pancreas, liver, digestive system, and reproductive tract. Alterations in the CFTR gene result in altered production, misfolding, or function of the protein and consequently abnormal fluid and ion transport across cell membranes. As a result, CF patients produce thick, sticky mucus that clogs the ducts of organs where it is produced making patients more susceptible to complications such as infections, lung damage, pancreatic insufficiency, and malnutrition.Basic Info-
Product Name:
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide
Other Name:Cyclopropanecarboxamide,1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-;1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide;VX 661;Tezacaftor;(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide;1537189-39-1;2135573-72-5
CAS No.:1152311-62-0
Molecular Formula:C26H27F3N2O6
InChIKeys:InChIKey=MJUVRTYWUMPBTR-MRXNPFEDSA-N
Molecular Weight:520.4975896
Exact Mass:520.50
UNII:8RW88Y506K
DSSTox ID:DTXSID40673070
ATC Code:R07AX31|R07AX
Categories:
Characteristics-
PSA:
113
XLogP3:99
Density:1.49±0.1 g/cm3(Predicted)
Boiling Point:610.8ºC at 760 mmHg
Flash Point:323.2±31.5 °C
Refractive Index:1.628
Water Solubility:H2O: Insoluble
Dissociation Constants:13.99, 0.19
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
-
Location:
https://www.dideu.com/en/
-
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
7 days
-
Total Annual Revenue:
Above $100 million
-
Total Employees:
Above 1000
-
Year of Establishment:
2016
Company Certificates-
ISO Certificate
-
REACH
">Company Profile -
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
More from this Seller
-
-
-
Paracetamol Acetaminophen CAS 103-90-2 BP USP EP API Grade
Pharmaceutical Grade / 99%
$150/KG EXW
-
-
-
-
Methyl 3-methyl-2-butenoate CAS 924-50-5 high-quality plant extract, reliable bulk and sample supply for global buyers
Pharmaceutical Grade / 99.9%
$1/MT FOB
-
-
-
-
Piroctone olamine CAS68890-66-4 high-quality plant extract, reliable bulk and sample supply for global buyers
Pharmaceutical Grade / 99.9%
$1/MT FOB
-
-
-
-
4-Methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one CAS 50650-75-4 high-quality plant extract, reliable bulk and sample supply for global buyers
Pharmaceutical Grade / 99.9%
$1/MT FOB
-
-
-
-
High quality Mirabegron CAS NO 223673-61-8
API / 99.5%
-