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Email: domi@xtjytech.com
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Xingtai Junyi Technology Co.，Ltd. Was established in 2019. It mainly deals in peptide products, synthetic peptide amino acids, beauty and slimming products, and beauty freckle removal cosmetic raw materials. It has strong R&D capabilities, superb synthesis technology, and advanced quality control methods. It effectively promotes joint ventures with major companies and manufacturers, and serves the society and users with the concept of industrial development. It always adheres to market demand-oriented, continuously synthesizing new high-tech freckle and wrinkle removal beauty peptide products, which are mainly exported to the United States, Europe, South Africa, Nigeria and other countries and regions. It has rich export experience and ensures transportation safety.
Retatrutide (LY3437943) acetate is a triple agonist peptide for the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R).
Retatrutide acetate inhibits human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643, and 0.775 nM, respectively. It exhibits activity on mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191, and 0.794 nM, respectively.
In vivo, Retatrutide (LY3437943) acetate engages with GCGR and enhances glucose tolerance in an ipGTT by acting through GIP or GLP-1 receptors. Activation via the glucagon receptor by Retatrutide acetate leads to significant weight reduction and increased energy expenditure. Retatrutide acetate can be utilized in research related to obesity.
Retatrutide achieves comprehensive metabolic regulation through triple receptor activation:
※ GLP-1R: Slows gastric emptying, enhances satiety, and reduces appetite.
※ GIPR: Regulates hunger signals in the central nervous system, further suppresses appetite and improves energy metabolism.
※ GCGR: Promotes glucagon secretion, accelerates fat and glycogenolysis, and increases basal metabolic rate.
CAS: 2381089-83-2
Molecular Formula: C221H342N46O68
Molecular Weight: 4731.33
Sequence: H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Appearance: White Powder
Purity (HPLC): ≥99.0%
Single Impurity (HPLC): ≤1.0%
Sodium Content (HPLC): 5.0%-12.0%
Moisture Content (Karl Fischer): ≤10.0%
Peptide Content: ≥80.0%
Storage: Store at 2-8 degrees Celsius in a dry and cool place.
Packaging: 1g-1kg, plastic bottle
Intended Use: For scientific research purposes
Clinical data |
Other names | LY-3437943 |
Identifiers |
CAS Number | |
UNII | |
ChEMBL | |
Chemical and physical data |
Formula | C223H343F3N46O70 |
Molar mass | 4845.444 g·mol −1 |
Indications and Efficacy:
Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.
Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.
Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.
Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.
Q: How to store it?
A: If it hasn't been opened, just put it in cool dry place, if it is opened, you may put it in cold storage for 2-5 degree condition.
Q: How to order this product?
A: You can click "contact Supplier" , or write an email to my inbox, and send us a inquiry, leave your number if possible, we will contact with you as soon as possible, then we can talk order details.
Q: How about the delivery time?
A: Shipped within 48 hours after payment is received.Small orders are shipped via express door-to-door.The goods arrive in about7-10 days.
Q ： ls cash on delivery ?
A:in most cases,we don't support cash on delivery.
Q: How much is the commodity?
A: As we all know, the price of chemicals is not fixed, but fluctuates with the market.
You need to contact me to get the latest product price, we promise to give you the most favorable price.
Q:About the after-sale service?
A:After purchasing the products from our Company, we have a professional technical team and after-sales team to serve you and solve all your problems in the future.
About us
Xingtai Junyi Peptides Technology Co.,Ltd is a leading and dedicated pharmaceutical distributor committed to improving patient outcomes by facilitating access to innovative and life-changing medications. We specialize in the reliable, compliant, and efficient sourcing and distribution of high-demand therapeutics, with a core focus on patide.
Our Mission
Our mission is to bridge the gap between cutting-edge pharmaceutical innovation and the healthcare providers and patients who need it most. We achieve this by ensuring a seamless, secure, and transparent supply chain for critical medications like Retatrutide, adhering to the highest standards of quality, regulatory compliance, and ethical business practices.
Core Focus: patide Expertise
Patide represents a significant advancement in metabolic disease treatment. As specialists in this vital medication, we offer:
Reliable Supply:We maintain robust partnerships and supply chain networks to ensure consistent availability of genuine Retatrutide.
Regulatory Compliance:We operate with strict adherence to all national and international regulations governing the pharmaceutical trade, including licensing, cold chain management (where applicable), and documentation.
Quality Assurance: We guarantee the authenticity and integrity of our products, sourcing only from authorized and vetted channels. Quality control is paramount at every stage.
Market Knowledge:Our team possesses deep expertise in the Retatrutide market, its indications, and the evolving needs of healthcare providers and payers.
Efficient Distribution:We leverage optimized logistics to deliver Retatrutide safely and promptly to pharmacies, hospitals, clinics, and authorized healthcare facilities.
Who We Serve: We partner with:
Pharmacies (Retail, Hospital, Specialty): Providing a dependable source for fulfilling patient prescriptions.
Hospitals and Healthcare Systems: Supporting formularies and patient care protocols requiring Retatrutide.
Wholesalers & Distributors: Acting as a key supplier within the pharmaceutical supply chain.
Authorized Healthcare Providers:Facilitating access for clinics and practices treating eligible patients.
Our Commitment:
Patient-Centricity: Ultimately, our work enables better patient access to transformative therapies like Retatrutide.
Integrity: We conduct business with transparency, honesty, and unwavering ethical standards.
Partnership: We strive to build long-term, collaborative relationships based on trust and mutual success with our clients.
Excellence: Continuous improvement in our processes and services is fundamental to our operations.
Why Partner With Us for patide?
Choose Xingtai Junyi Peptides Technology Co.,Ltd for your patide supply needs and benefit from our specialized focus, proven reliability, stringent compliance, and commitment to excellence. We are more than a distributor; we are a dedicated partner in advancing metabolic health.
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