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PDRN CAS: 100403-24-5

1. Product introduction:

Product name: PDRN

Other names:   DEOXYRIBONUCLEIC ACID

CAS: 100403-24-5  

Purity:  ≥99%min

Grade:   cosmetic  grade

MF:   N/A

MW: N/A  

Shelf life: 2 years

Appearance: White powder

2.Description:

PDRN (polydeoxyribonucleotide) is a DNA fragment extracted from salmon germ cells or salmon seminal vesicles. Its base composition is 98% similar to human DNA. This characteristic makes it a highly biocompatible renewable material, known as the 'life repair factor in the ocean'.

Molecular structure: Composed of long-chain polymers ranging from 50-1500kDa, appearing as white powder or fibrous solid, soluble in water.

1. Application :

Anti inflammatory, repairing, anti-aging trio

PDRN activates cell regeneration through a dual pathway:

Adenosine A2A receptor activation:

The adenosine released after decomposition binds to the A2A receptor on the cell membrane, inhibiting the expression of pro-inflammatory factors such as TNF - α and IL-6, while promoting the secretion of anti-inflammatory factors such as IL-10, significantly inhibiting the inflammatory response

Nucleotide remediation pathway:

The nucleotides and bases produced by decomposition directly participate in DNA repair and synthesis, especially in hypoxic or damaged cells, by supplementing purine and pyrimidine libraries, accelerating cell proliferation and tissue regeneration.

1. Core application scenarios

Medical beauty:

1. Repair skin damage: reduce scar formation, improve complex scars such as acne scars and ice cone scars, with a patient satisfaction rate of over 85%.

2. Anti aging: By activating fibroblasts, the synthesis of collagen increases by 2-3 times, while inhibiting the degradation of collagen by MMP-1, improving skin laxity and fine lines.

3. Sensitive muscle repair: Combined with salicylic acid, compound acid, or photoelectric radiofrequency instruments, it inhibits the release of inflammatory factors, repairs damaged cells, and strengthens the skin barrier.

Daily chemical products:

1. As an active ingredient in cosmetics, it is added to gel, essence, lotion, facial mask, etc. to improve the hydration ability of skin and reduce the generation of fine lines and wrinkles.

5 . Packing and shiping :

Generally, the product will be packed in two plastic bags and one foil bag, and then a fiber drum for 25kg.