Veterinary API 99% GS-441524 1191237-69-0

GS-441524 More Info

GS-441524 (CAS No. 1191237-69-0) is a nucleoside analogue with demonstrated antiviral activity, originally developed as a therapeutic agent for veterinary applications. Structurally related to adenosine, this small molecule compound functions as a RNA-dependent RNA polymerase inhibitor, exhibiting specific activity against certain single-stranded RNA viruses. The compound gained significant attention during recent years due to its potential application in treating coronavirus infections in animals. Its molecular design allows for intracellular conversion to the active triphosphate form, which competitively inhibits viral replication while maintaining relatively low cytotoxicity in mammalian cells compared to similar antiviral compounds.

Application Fields

The primary veterinary application of GS-441524 focuses on the treatment of feline infectious peritonitis (FIP), a previously fatal coronavirus disease in cats. Clinical studies have shown remarkable efficacy in both effusive and non-effusive forms of FIP when administered as an injectable or oral formulation. Emerging research explores potential applications against other coronavirus infections in various animal species. While not currently approved for human use, the compound serves as an important research tool for studying coronavirus replication mechanisms and evaluating potential therapeutic approaches for related viral diseases.

Market Landscape

The market for GS-441524 operates primarily within the veterinary pharmaceutical sector, with growing demand from specialty compounding pharmacies and veterinary clinics worldwide. Despite lacking formal regulatory approval in many jurisdictions, the compound has become widely used off-label for FIP treatment, creating a unique market dynamic. The increasing prevalence of FIP diagnoses and successful treatment outcomes have driven significant interest from animal health companies considering formal drug development. Current production is concentrated in specialized API manufacturers, with quality control being a critical factor due to the compound's sensitive nature and therapeutic importance.

Regulatory & Handling Considerations

As an unapproved investigational compound in most regions, GS-441524 requires careful handling under appropriate regulatory frameworks for research chemicals. Manufacturers must implement strict quality control measures to ensure purity and consistency, particularly when producing material for therapeutic use. Special storage conditions (typically -20°C protected from moisture) are necessary to maintain compound stability. Veterinary professionals using this material should be aware of potential legal and liability considerations regarding off-label use. Transportation typically follows general chemical safety protocols rather than specific hazardous material classifications, though proper documentation of contents is essential for international shipments.

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Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.