(R)-3-(3-fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one RC00185

Manufacturer: Hangzhou Royalchem Co.,LTD.

Website:  www.cnroyalchem.com

【 Providing a complete set of intermediates and impurities for Tedizolid 】

【 Providing a complete set of intermediates and impurities for Tedizolid 】

【 Providing a complete set of intermediates and impurities for Tedizolid 】

Based on the search results, here is the detailed product information for  168828-72-6 ((R)-3-(3-fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one) :

1.  Basic Information

CAS Number : 168828-72-6

Molecular Formula : C 14 H 17 FN 2 O 3 S

Molecular Weight : 312.36 g/mol 

MDL Number : MFCD08234639 

2.  Chemical Names and Synonyms

IUPAC Name :
(5R)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one

Common Synonyms :

(R)-3-(3-Fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one

(R)-{3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl}methanol

(S)-3-(3-fluoro-4-thiomorpholinophenyl)-4-(hydroxymethyl)oxazolidin-2-one  (Note: Stereoisomer)  

3.  Physicochemical Properties

Density : 1.381 ± 0.06 g/cm³ (Predicted) 

Melting Point : 520.1 ± 50.0 °C (Predicted)

pKa : 14.05 ± 0.10 (Predicted) 

Appearance : Solid (typically white to pale red) 

4.  Synthetic Routes

Two primary methods are reported:

From (R)-(-)-Glycidyl Butyrate :

Yield: ~78% .

From 3,4-Difluoronitrobenzene :

Specific yield not disclosed .

5 .  Structural and Safety Data

Storage : Recommended at 2–8°C .

Handling : Use standard lab precautions for handling fluorinated/organosulfur compounds.