High Quality Riociguat CAS 625115-55-1 99% Assay White Powder API in Stock
3 Inquiries
625115-55-1
Pharmaceutical Grade
99%
Shanghai
HyperChem
1kg/Bag, 25kg/drum
2025-09-03
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceRiociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension.
Riociguat is a carbamate ester that is the methyl ester of {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamic acid. It is used for treatment of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension It has a role as a soluble guanylate cyclase activator and an antihypertensive agent. It is a pyrazolopyridine, an aminopyrimidine, an organofluorine compound and a carbamate ester.|Riociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO FC II or III. Riociguat is marketed under the brand Adempas® by Bayer HealthCare Pharmaceuticals. Treatment with riociguat costs USD $7,500 for 30 days of treatment.|Riociguat is a Soluble Guanylate Cyclase Stimulator. The mechanism of action of riociguat is as a Guanylate Cyclase Stimulator.|Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension. Riociguat has not been linked to significant serum enzyme elevations during therapy or to instances of clinically apparent acute liver injury.Basic Info-
Product Name:
Riociguat
Other Name:Carbamic acid,N-[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-,methyl ester;Carbamic acid,[4,6-diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]methyl-,methyl ester;Riociguat;BAY 632521;BAY 63-2521;Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate;Adempas;Methyl N-[4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-(methyl)carbamate;911138-23-3
CAS No.:625115-55-1
Molecular Formula:C20H19FN8O2
InChIKeys:InChIKey=WXXSNCNJFUAIDG-UHFFFAOYSA-N
Molecular Weight:422.4156632
Exact Mass:422.42
EC Number:1308068-626-2
UNII:RU3FE2Y4XI
ATC Code:C02KX05|C - Cardiovascular system
Categories:
Characteristics-
PSA:
138
XLogP3:1.6
Density:1.51
Boiling Point:567.2°C at 760 mmHg
Flash Point:296.8±30.1 °C
Refractive Index:1.720
Water Solubility:4 mg/L at 25°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements
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Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2013
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Certifications:
Certification Report by Bureau Veritas
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Bulgaria
Riociguat
10 G Aug 18, 2025 
Portugal
riociguat
10 G Jun 9, 2025
Bulgaria
Riociguat
10 G Jul 23, 2025 Post an enquiry for this product
