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Factory Supply Cosmetic Raw Material CAS 98-92-0 99% High Quality OEM Nicotinamide Powder

Name: Factory Supply Cosmetic Raw Material CAS 98-92-0 99% High Quality OEM Nicotinamide Powder
Brand: SINOV
SKU: pr2508281333
Price: 100 USD
Availability: InStock

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CAS No.:

98-92-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Qingdao

Brand:

SINOV

Packaging:

1vial

Price valid (until):

2025-09-28

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Description
Seller Information
Inquiry History

Description

Product Detail

1. Description

Nicotinamide, also known as nicotinamide, vitamin B3, or vitamin PP, is a water-soluble vitamin belonging to the B vitamin family. It is a constituent of coenzyme I (nicotinamide adenine dinucleotide, NAD) and coenzyme II (nicotinamide adenine dinucleotide phosphate, NADP). In the human body, the nicotinamide moiety in these two coenzyme structures exhibits reversible hydrogenation and dehydrogenation properties. It plays a role in hydrogen transfer during biological oxidation, promoting tissue respiration, biological oxidation processes, and metabolism. It is crucial for maintaining the integrity of normal tissues, especially the skin, digestive tract, and nervous system. When deficient, it can cause rough skin due to affected cellular respiration and metabolism. Therefore, this product is mainly used to prevent and treat rough skin, stomatitis, glossitis, and other conditions.

2. Application

Nicotinamide and nicotinic acid are commonly used under most conditions, and nicotinic acid is also converted into nicotinamide in the body of animals. When there is a deficiency of nicotinic acid and nicotinamide in the body, pellagra can occur. Therefore, they can prevent pellagra. They play a role in the metabolism of proteins and sugars, and can improve the nutrition of humans and animals. In addition to being used in medicine, they are also widely used as food and feed additives. The global production capacity has exceeded 30,000 tons. In Japan, nicotinamide is used for 40% of medicine, 50% of feed additives, and 10% of food additives. Nicotinic acid and nicotinamide are non-toxic and are naturally found in animal livers, kidneys, yeast, and rice sugar. The LD50 of nicotinamide for subcutaneous injection in rats is 1.7 grams/kilogram.

3. Main Efficacy

The whitening principle of niacinamide primarily lies in two aspects: Firstly, niacinamide can interfere with the transportation of melanin, confining it within melanocytes and preventing melanocytes from continuously producing melanin. This, in turn, avoids the transfer of melanin to the surface of the skin, which can cause skin darkening, thus achieving a whitening effect. Secondly, niacinamide has been proven to exhibit excellent anti-glycation properties. Glycation in the skin produces substances that are brown in color, making the skin appear darker. Niacinamide's anti-glycation properties contribute to skin whitening, thereby brightening the skin tone. Shop Professional Factory Supply High Qulity Bengenin-Detailed Image 2

Items	Specifications
Origin	China
Purity	5%-99%
Appearance	Powder
Color	White
Package	Drum, Plastic Container, Vacuum Packed
Shelf life	2 years
Storage	Cool Dry Place

ECHEMI Editorial Reference

It is white needle crystal or crystalline powder, no smell or odor slightly, slightly bitter taste. The relative density is 1.4, melting point is 131-132 ℃.1 g of the above the product is soluble in 1 ml of water, 1.5 ml ethanol or 10 ml glycerin, insoluble in ether. The pH of 10% aqueous solution is 6.5-7.5. in dry air to light and heat stability, in alkaline or acidic solution, heating generation to nicotinic acid. Rats by oral LD502.5-3.5g/kg ADI value does not make special provisions (ECC,
Nicotinamide is a white powder. (NTP, 1992)|DryPowder; OtherSolid|Solid|WHITE CRYSTALLINE POWDER.
Nicotinamide is a white powder. (NTP, 1992)|Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It derives from a nicotinic acid.|Mediatric is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.|Vitamin B refers to several water soluble vitamins often found together in foods, all of which are necessary for normal growth and metabolism, but none of which are synthesized in adequate amounts by humans. The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice. The major forms of vitamin B and selected other water soluble vitamins (biotin, pantothenic acid, choline) are discussed briefly in this record.|Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Basic Info

Product Name:

Nicotinamide

Other Name:

3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

CAS No.:

98-92-0

Molecular Formula:

C6H6N2O

InChIKeys:

InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

Molecular Weight:

122.12500

Exact Mass:

122.12

EC Number:

202-713-4

UNII:

25X51I8RD4

DEA Code Number:

1405

ICSC Number:

1703

NSC Number:

759115|27452|13128

DSSTox ID:

DTXSID2020929

NCI Thesaurus Code:

C2327

Color/Form:

White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

ATC Code:

A11HA01|A - Alimentary tract and metabolism

HScode:

2933399090

Categories:

Amino Acids and Proteins

Characteristics

PSA:

55.98000

XLogP3:

0.88080

Appearance:

Nicotinamide is a white powder. (NTP, 1992)

Density:

1.400 g/cm³ @ Temp: 25 °C

Melting Point:

130 °C

Boiling Point:

157 °C @ Press: 5 x 10^-4 Torr

Flash Point:

182°C

Refractive Index:

1.4660 (estimate)

Water Solubility:

1000 g/L (20 ºC)

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Vapor Pressure:

Vapour pressure, kPa at 35°C: 3.1

Vapor Density:

Relative vapour density (air = 1): 4.2

Toxicity:

LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

Odor:

Odorless

Taste:

Bitter taste

PH:

10% "wt in vol" solution in water is neutral to litmus

PKA:

3.35(at 20 °C)

Henrys Law Constant:

Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

Dissociation Constants:

3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

Collision Cross Section:

125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Å² [M+H]+

Experimental Properties:

Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

Air and Water Reactions:

Water soluble.

Reactive Group:

Amides and Imides

Reactivity Profile:

An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Autoignition Temperature:

480 °C

Physical Dangers:

Dust explosion possible if in powder or granular form, mixed with air.

See More Nicotinamide Properties 

Hazard Identification

Classification of the substance or mixture

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Separated from oxidants.

See More Nicotinamide Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

107 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Nicotinamide	45.00 KG	Jun 13, 2025
India	Nicotinamide	25.00 KG	Jun 12, 2025
India	Nicotinamide	50.00 KG	Jun 11, 2025
India	Nicotinamide	50.00 KG	Jun 13, 2025
United States	Niacinamide	1 KG	Feb 5, 2024
India	Nicotinamide	25.00 KG	Jun 11, 2025
Egypt	Niacinamide	1.00 KG	Aug 28, 2026
Russia	Niacinamide	1 KG	Dec 2, 2024
India	Niacinamide	100.00 KG	Aug 3, 2026
Pakistan	Niacinamide	5.00 KG	Sep 14, 2026
India	Niacinamide	200.00 KG	Sep 2, 2026
India	Niacinamide	1.00 KG	Aug 22, 2026
Nigeria	Niacinamide	100.00 KG	Aug 20, 2026
Uganda	Niacinamide	500 G	Aug 13, 2026
Pakistan	Niacinamide	10.00 MT	Jul 10, 2026
India	Nicotinamide	1 KG	Jul 1, 2026
South Korea	Niacinamide	150 KG	Jun 29, 2026
India	Niacinamide	1.00 MT	Jun 26, 2026
Nigeria	Niacinamide	100.00 KG	Jun 22, 2026
India	Niacinamide	1.00 KG	Jun 1, 2026

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Factory Supply Cosmetic Raw Material CAS 98-92-0 99% High Quality OEM Nicotinamide Powder

Product Description

Seller Information