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Home > Organic Chemistry > Aldehydes > 3,3-Bis(4-hydroxyphenyl)phthalide for Sale > Chemical Intermediate Medicine Raw Powder CAS 77-09-8 Medical Grade Phenolphthalein
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Chemical Intermediate Medicine Raw Powder CAS 77-09-8 Medical Grade Phenolphthalein

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CAS No.:

77-09-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Tianjin

Brand:

Goldstar

Packaging:

25kg per bag

Price valid (until):

2026-04-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

silver mercury,Cellulose acetate tow,SLES,LABSA,soap noodles,Lithium hydroxide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Phenolphthalein is a chemical that is commonly used as a colorimetric pH indicator. The compound has been observed to turn orange at pH <0, clear between pH 0-8.2, fuchsia between pH 8.2-12, and clear again at a pH above 12. It has been postulated that the mutagenic effects of Phenolphthalein at high doses can be attributed the enhancement intracellular free oxygen radicals. The compound has also been observed to induce mitotic abnormalities and micronuclei with kinetochores in vitro. In Syrian hamster embryos treated with 10-40 μM of Phenolpthalein a significant number of chromosomal aberrations occurred at the hprt locus. On human breast cancer cells Phenolphthalein has been observed to have weak estrogenic effects.
    Uses: acid-base indicator, chromatography reagents, organic synthesisl industry (such as the manufacture of laxatives)


    Items Standards
    Characteristics A white or almost white powder, practically insoluble in water, soluble alcohol.
    Melting Point It melts at about 260ºC
    Appearance of Solution The solution is clear and not more intensely coloured than reference solution Y7.
    Related Substances Less than 0.5%
    Heavy Metals Not mare than 0.001%
    Acidity or Alkalinity Complies
    Chlorides Not more than 0.01%
    Sulphates Not more than 0.02%
    Loss on Drying Not more than 0.5%
    Sulphated Ash Not more than 0.1%
    Assay 98.0%-101.0%(C20H1404)
    Microorganism TPC<1000cfu/g
    Y and M <100cfu/g
    E-coli - absent
    Staphylococcus Aureus - Absent
    Pseudomonas Aeruginosa - Absent
    Albicans Saccharomyces - Absent
    Package In 25KG drum



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     Specifications  


    TEST ITEM

    SPECIFICATION

    RESULTS

    Characteristics

    A white or almost white powder, practically insoluble in water, soluble in alcohol.

    A white powder, practically insoluble in water, soluble in alcohol.

    Melting Point

    It melts at about 260°C.

    261ºC.~262ºC.

    Identification

    A:Positive

    B:Positive

    A:Positive

    B:Positive

    Appearance of solution

    The solution is clear and not more intensely coloured than reference solution Y7

    Complies

    Related substances

    Less than 0.5%

    <0.5%

    Heavy metals

    Not more than0.001%

    <0.001%

    Acidity or alkalinity

    Complies

    Complies

    Chlorides

    Not more than 0.01%

    <0.01%

    Sulphates

    Not more than 0.02%

    <0.02%

    Loss on drying

    Not more than 0.5%

    0.12%

    Sulphated ash

    Not more than 0.1%

    0.01%

    Assay

    98.0%-101.0%(C20H14O4)

    99.6%


      Application  


    The pharmaceutical raw materials in pharmaceutical industry: it is suitable for habitual stubborn constipation, including tablets, suppositories and other formulations.

    1. It can be used for organic synthesis: mainly used in synthesizing plastics, especially in synthesizing the phthalazinone poly aryl ether ketone poly aryl ether ketone polymers. This kind of polymers, because of its excellent heat resistance, water resistance, corrosion resistance, heat aging resistance and good processability, fibers, coatings and composites made of it are widely used in the fields of electrical and electronic equipment, transportation and aerospace, atomic energy engineering.
    2. Used as acid and alkali indicator, non-aqueous solution titration indicator and chromatography analysis reagents.





      Package Detail  






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     Company Profile  



    Hebei Goldstar Technology Co.,Ltd. We are located in Hebei with convenient transportation access. We are a professional manufacturer and trader that is concerned with the research, development and production of chemical products. We committed to providing you with high-quality products and services. We always implement the concept of customer value creation, for customers tailored products,
    to meet the needs of different customers, and continuously provide customers with solutions and technical problems.Further exploration and innovation, and excellence.Welcome and look forward to customers from all of the world to contact us for create a bright future with us together.


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    Certificates

    Basic Info
    Product Name:

    3,3-Bis(4-hydroxyphenyl)phthalide

    Other Name:

    1(3H)-Isobenzofuranone,3,3-bis(4-hydroxyphenyl)-;Phenolphthalein;3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone;3,3-Bis(4-hydroxyphenyl)phthalide;Purga;Laxogen;Spulmako-lax;Lilo;Trilax;Koprol;Purgophen;Euchessina;Phthalimetten;Purgen;Phthalin;3,3-Bis(p-hydroxyphenyl)phthalide;NSC 10464;NSC 215214;TY 9;PX 0520-1;3,3-Bis-(4-hydroxy-phenyl)-3H-isobenzofuran-1-one;3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1-one;467-29-8;57214-20-7;390417-24-0;546094-13-7;1541170-18-6

    CAS No.:

    77-09-8

    Molecular Formula:

    C20H14O4

    InChIKeys:

    InChIKey=KJFMBFZCATUALV-UHFFFAOYSA-N

    Molecular Weight:

    318.32

    Exact Mass:

    318.32

    BRN:

    284423

    EC Number:

    201-004-7

    UNII:

    6QK969R2IF

    NSC Number:

    757271|215214|10464

    UN Number:

    1993

    DSSTox ID:

    DTXSID0021125

    NCI Thesaurus Code:

    C29359

    Color/Form:

    White or yellowish-white minute, triclinic crystals, often twinned|White rhombic needles|Pale yellow powder

    ATC Code:

    A - Alimentary tract and metabolism

    HScode:

    29322910

    Categories:

    Aldehydes

    Characteristics
    PSA:

    66.8

    XLogP3:

    3.6

    Appearance:

    White to yellow-white Solid

    Density:

    1.277 g/cm3 @ Temp: 32 °C

    Melting Point:

    262.5 °C

    Boiling Point:

    557.8±50.0 °C at 760 mmHg

    Flash Point:

    24 °C

    Refractive Index:

    1.693

    Water Solubility:

    H2O: <0.1 g/100 mL;soluble in alcohol. Slightly soluble in ether. Slightly soluble in dimethyl sulfoxide and insoluble in benzene or hexane.

    Storage Conditions:

    Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ) that bears appropriate label. An inventory should be kept, showing quantity of carcinogen & date it was acquired Facilities for dispensing should be contiguous to storage area.

    Vapor Pressure:

    6.7X10-13 mm Hg @ 25 deg C /Estimated/

    Odor:

    ODORLESS

    PKA:

    9.7(at 25 °C)

    Henrys Law Constant:

    Henry's Law constant = 9.0X10-16 atm-cu m/mol @ 25 °C /Estimated/

    Dissociation Constants:

    9.7 (at 25 °C)|pKa = 9.7 at 25 °C

    Collision Cross Section:

    172.1 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Solutions are colorless to pH 8.5; pink to deep-red, above pH 9|Forms an almost colorless solution in neutral or acid solution, pink to deep red in presence of alkali, but colorless in the presence of large amounts of alkali.|Hydroxyl radical reaction rate constant = 8.4X10-11 cu cm/molecule-sec @ 25 °C /Estimated/

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

    Reactivity Profile:

    PHENOLPHTHALEIN is incompatible with alkaloids. (NTP, 1992)

    Hazard Identification

    Classification of the substance or mixture

    Germ cell mutagenicity, Category 2

    Carcinogenicity, Category 1B

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H341 Suspected of causing genetic defects

    H350 May cause cancer

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    PRECAUTIONS FOR "CARCINOGENS": Storage site should be as close as practical to lab in which carcinogens are to be used, so that only small quantities required for ... expt need to be carried. Carcinogens should be kept in only one section of cupboard, an explosion-proof refrigerator or freezer (depending on chemicophysical properties ...) that bears appropriate label. An inventory ... should be kept, showing quantity of carcinogen & date it was acquired ... Facilities for dispensing ... should be contiguous to storage area. Chemical Carcinogens

  • Seller Information
    Business Type:

    Trader

    Main Products:

    silver mercury,Cellulose acetate tow,SLES,LABSA,soap noodles,Lithium hydroxide

    Location:

    Room 2701, Building4,Tatan International Trade Plaza, South of Shengli street, Qiaoxi District ,Shijiazhuang city

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    15

    Total Annual Revenue:

    $10 million-$25 million

    Total Employees:

    11-50

    Year of Establishment:

    2020

    Management principles
    Our company offers a variety of products which can meet your multifarious demands. We have adhered to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy the potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with an irresistible force.

    Passed the ISO 9001: 2008 certificate
    We specialize in chemical products that have covered most regions of China and exported to foreign countries and regions such as Europe, USA and Southeast Asia. For many years, the company has taken advantage of its merits to develop high-tech well-known products. Our capacity and efficiency have been improved rapidly. The National Ministry of Science and Technology named our company "National Key High-tech Enterprise" in 2003. The company has passed the ISO 9001: 2008 certificate of CQC.

    Business philosophy
    We will continue to focus the development on the principle of an "energy-saving, emission reducing and recycling economy", to insist on independent innovation and technology-driven, to covert practical resources and technical advantages into an industrial advantage, and to combine reasonably the economic benefits with society. At the same time, Loman Corp. will practice our struggle goal of "the super excellent Loman, the global Loman, the centennial Loman".

    Comply with ISO 9001 and ISO 2000 standards
    We now have more than 80 people in our team and built research centers in Jinan and Qingdao. Our manufacturing site is allocated to the chemical industry parks of Zhangqiu, Heze, Dezhou and Ningxia Fine Chemical Park. We strictly comply with ISO 9001 and ISO 2000 standards in the manufacturing process, and our lab and workshop are tightly in accordance with GMP standards. Our products are best selling in Europe, South and North America, Asia Pacific area and Africa. We sincerely welcome new and regular customers around the world to visit us for business negotiation.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Phenolphthalein

    25.00 KG Oct 12, 2025
    Post an enquiry for this product
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