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Dapagliflozin base 461432-26-8

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Unit Price: Get Latest Price
CAS No.:

461432-26-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Zentrachem

Packaging:

25kgs in drum

Price valid (until):

2025-10-29

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,100% TT in advance
Average Lead Time:
14 days
Qualification:
Main Products:

pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    samples available


     we are capable of:


    1) quick quotation, normally within 1-2 days

    2) full marketing research

    3) price control and quality(regulatory) control

    4) all stage support from sample, pilot, registration and commercial

    5) sourcing for prodcut which is very new or hard to find

    6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing



    What are the MOQ and lead time?


    MOQ varies (high-value chemicals may negotiate to g-kg-level).

    Lead time typically 2-4 weeks, with expedited options upon request.


    How do we ensure product quality and compliance?


    We enforce a 3-step protocol:

    ① Source only from ISO-certified suppliers;

    ② Provide batch-specific COA/COO;

    ③ Dedicated team monitors global regulations (e.g., China NECIC, EU SCIP).


    Do we offer customized synthesis?


    Yes!

    We provide end-to-end solutions from R&D to scale-up production.

    Technical specs (e.g., purity, CAS#) and intended use documentation are required.


    How do we handle logistics and customs?


    We support CIF/FOB/DDP/DAP terms, partner with global logistics providers,

    and have in-house experts for HS code classification, hazardous material documentation, etc.


    How do we manage raw material price fluctuations?


    We mitigate risks via long-term contracts, multi-region sourcing,

    and futures hedging, supplemented with quarterly market analysis reports.

    Items Specifications






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    ECHEMI Editorial Reference
    Dapagliflozin (BMS-512148) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.
    Dapagliflozin is a C-glycosyl comprising beta-D-glucose in which the anomeric hydroxy group is replaced by a 4-chloro-3-(4-ethoxybenzyl)phenyl group. Used (in the formo f its propanediol monohydrate) to improve glycemic control, along with diet and exercise, in adults with type 2 diabetes. It has a role as a hypoglycemic agent and a sodium-glucose transport protein subtype 2 inhibitor. It is a C-glycosyl compound, an organochlorine compound and an aromatic ether.|Dapagliflozin is a sodium-glucose cotransporter 2 inhibitor indicated for managing diabetes mellitus type 2. When combined with diet and exercise in adults, dapagliflozin helps to improve glycemic control by inhibiting glucose resorption in the proximal tubule of the nephron and causing glycosuria. Dapagliflozin was approved by the FDA on Jan 08, 2014.|Dapagliflozin is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of dapagliflozin is as a Sodium-Glucose Transporter 2 Inhibitor.|Dapagliflozin is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Dapagliflozin selectively and potently inhibits SGLT2 compared to SGLT1, which is the cotransporter of glucose in the gut.

    Certificates

    Basic Info
    Product Name:

    Dapagliflozin

    Other Name:

    D-Glucitol,1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-,(1S)-;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol;Dapagliflozin;BMS 512148;(2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol;2195352-53-3

    CAS No.:

    461432-26-8

    Molecular Formula:

    C21H25ClO6

    InChIKeys:

    InChIKey=JVHXJTBJCFBINQ-ADAARDCZSA-N

    Molecular Weight:

    408.875

    Exact Mass:

    408.87

    EC Number:

    1592732-453-0

    UNII:

    1ULL0QJ8UC

    NCI Thesaurus Code:

    C78126

    ATC Code:

    A10BD|A10BK01|A - Alimentary tract and metabolism

    Characteristics
    PSA:

    99.4

    XLogP3:

    2.3

    Density:

    1.349

    Melting Point:

    65

    Boiling Point:

    609°C

    Flash Point:

    322.1±31.5 °C

    Refractive Index:

    1.614

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 4, Oral

    Eye irritation, Category 2

    Reproductive toxicity, Category 1B

    Reproductive toxicity, Additional category for effects on or via lactation

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H302 Harmful if swallowed

    H319 Causes serious eye irritation

    H360 May damage fertility or the unborn child

    H362 May cause harm to breast-fed children

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P263 Avoid contact during pregnancy and while nursing.

    Response

    P301+P317 IF SWALLOWED: Get medical help.

    P330 Rinse mouth.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

    Location:

    Rm 301, Bld 2, Taohuahu Neighborhood Center, Hangzhou, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,100% TT in advance

    Average lead Time:

    14 days

    Total Employees:

    5-10

    Year of Establishment:

    2025

    Zentra Chemical, headquartered in Hangzhou, China, is aiming to be a global leader in chemical trading and integrated solutions.

    Specializing in Pharmaceutical intermediates, Agrochemical intermediates, Fine chemicals, and Cosmetic ingredients, we deliver end-to-end services spanning sourcing, supply chain optimization, customized synthesis, cost management, and quality assurance.

    Our mission is to empower clients worldwide with agile, sustainable, and value-driven partnerships in the ever-evolving chemical industry.


      Why us  


    Supplier, distributor & marketer of chemicals with >20 yrs of experience, with  Integrated sourcing solutions.

    Wide product range , We can source any fine chemical you require, unlimited range, including intermediates and products for agrochemicals, cosmetics, APIs, nanotechnology, additives, flavors, fragrances, photography, plant extracts, electronics industries and more.

    We can solve your sourcing problems through our own or third party manufacturing in the  most transparent way.

    We supply  all stage support from sample, pilot, registration and commercial.

    Through selected  pre-qualified partners  under exclusive arrangements, we offer  Contract manufacturing and custom synthesis , Kilo to Multi-ton scale production.


      Capability  


    with hundreds of local manufacturers(pre-qualified), we are capable of:

    1) quick quotation, normally within 1-2 days;
    2) full marketing research;
    3) price control and quality(regulatory) control;
    4) all stage support from sample, pilot, registration and commercial;
    5) sourcing for prodcut which is very new or hard to find;
    6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing.

  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    Austria

    Dapagliflozin

    1.00 G Jul 14, 2026
    United Arab Emirates

    Dapagliflozin

    5 KG Jul 15, 2026
    India

    Dapagliflozin

    0.10 G Jul 7, 2026
    India

    Dapagliflozin

    7 MT Nov 24, 2025
    United States

    Dapagliflozin

    10 G Jul 13, 2026
    India

    Zinc Carnosine

    50 KG Apr 23, 2026
    Germany

    Dapagliflozin

    1 KG Mar 31, 2026
    India

    Dapagliflozin

    1 KG Nov 5, 2024
    India

    Dapagliflozin

    200 KG Jun 12, 2024
    India

    Dapagliflozin

    15 KG Jun 5, 2026
    Portugal

    Dapagliflozin

    1 KG Jun 9, 2025
    Post an enquiry for this product
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