3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole
1 Inquiries
143322-58-1
shanghai
25kg/drums
2025-10-03
Dichloromethane,Linocaine hydrochloride
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceSolid
Solid
Eletriptan is an N-alkylpyrrolidine, that is N-methylpyrrolidine in which the pro-R hydrogen at position 2 is replaced by a {5-[2-(phenylsulfonyl)ethyl]-1H-indol-3-yl}methyl group. It has a role as a serotonergic agonist, a vasoconstrictor agent and a non-steroidal anti-inflammatory drug. It is a member of indoles, a N-alkylpyrrolidine and a sulfone. It is a conjugate base of an eletriptan(1+).|Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.|Eletriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist. The mechanism of action of eletriptan is as a Serotonin 1b Receptor Agonist, and Serotonin 1d Receptor Agonist.|The triptans are a group of serotonin receptor agonists that are useful in the therapy of vascular headaches and migraine. The triptans are generally used in low doses for a limited period of time and have not been associated with serum enzyme elevations, but some have been implicated in rare instances of clinically apparent, acute cholestatic hepatitis.Basic Info-
Product Name:
Eletriptan
Other Name:1H-Indole,3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-;1H-Indole,3-[(1-methyl-2-pyrrolidinyl)methyl]-5-[2-(phenylsulfonyl)ethyl]-,(R)-;3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethyl]-1H-indole;Eletriptan;UK 116044;(R)-5-[2-(Benzenesulfonyl)ethyl]-3-[(N-methylpyrrolidin-2-yl)methyl]-1H-indole
CAS No.:143322-58-1
Molecular Formula:C22H26N2O2S
InChIKeys:InChIKey=PWVXXGRKLHYWKM-LJQANCHMSA-N
Molecular Weight:382.52
Exact Mass:382.52
UNII:22QOO9B8KI
DSSTox ID:DTXSID9046861
ATC Code:N02CC06|N - Nervous system
Categories:
Characteristics-
PSA:
61.6
XLogP3:3.9
Appearance:yellow foam
Density:1.2±0.1 g/cm3
Boiling Point:613.4±55.0 °C at 760 mmHg
Flash Point:324.8±31.5 °C
Refractive Index:1.634
Water Solubility:Readily soluble as hydrobromide formulation
Storage Conditions:Hygroscopic, Refrigerator, Under Inert Atmosphere
Vapor Pressure:1.58E-16mmHg at 25°C
Collision Cross Section:186.1 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
Serious eye damage, Category 1
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H302 Harmful if swallowed
H318 Causes serious eye damage
H412 Harmful to aquatic life with long lasting effects
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P273 Avoid release to the environment.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Dichloromethane,Linocaine hydrochloride
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Location:
BUILDING 1,HISENSE INTELLIGENCE VALLEY,NO.2116,OF PHOEIX ROAD, HIGH-TECH ZONE ,JINAN CITY ,SHANDONG PROVINCE,CHINA
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Payment Terms:
D/P,L/C,D/A
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Average lead Time:
15
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2016
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Egypt
Eletriptan
25 KG Sep 2, 2025 Post an enquiry for this product