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Carmustine 154-93-8

KOSHER ISO FDA 2 Inquiries

Unit Price: Get Latest Price
CAS No.:

154-93-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shenzhen

Brand:

Flying

Packaging:

1kg

Sample Available:

Yes

Price valid (until):

2025-10-04

Company Type:
Trader
Location:
China
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
Average Lead Time:
25 days
Qualification:
Main Products:

vitamin

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Superiority

    1.High quality and competitive price.
    2.Free sample for your evaluation.
    3.Promptly delivery by well-reputed shipping lines.
    4.Trial order is available for testing after samples.
    5.We will inform you all the information at every stage in advance.
    6.Packaging can gear to buyers’ special request. 

    Our service

    1. Reply your inquiry in 24 working hours.
    2. Customized design is available. OEM are welcomed.
    3. Exclusive and unique solution can be provided to our customer by our well-trained and professional engineers and
    staff.
    4. Professional factory: We are manufacturer, specializing in producing all kinds of herb extract for more than 10 years, competitive with good quantity.
    5. As an honest seller, we always use superior raw material, advanced machines, skilled technicians to ensure our products to be finished in high quality and stable feature.


    Hainan Flying International Trade Co., Ltd., was established in 2020, It is a professional supplier of Human APIs, Veterinary, Food Additives, Vitamins, Chemicals, Plant Extract and natural active ingredients. It has absolute advantage because of strong research strength, modern management system and high-quality marketing team.

    For customer’s needs, OEM service is also acceptable. If you have a good idea in new product production but lack of laboratory device and human resource, we are glad to solve this problem for you. Sincerely hope to strengthen exchanges and cooperation with friends from both home and abroad.

    .






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    RAQ





    Q1: How to confirm the Product Quality before placing orders?
    A: By sending you available samples. Or if you have special requirements for the goods, we can prepare samples according to your requirement for confirmation.

    Q2: Can you supply free samples?
    A: Yes, we can provide a free sample, but the shipping cost will be paid by the customers. You can either pay the shipping cost or arrange a courier to collect the samples.

    Q3: How do you treat quality complaints?
    A: All our products are strictly tested by our QC and confirmed by QA; unqualified material will not be released to customers. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.

    Q4: What's your MOQ ?
    A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
    Q: Is there a discount ?
    A: Yes, for larger quantity, we always support with better price.

    Q5: How to start orders or make payments ?
    A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.


    ECHEMI Editorial Reference
    Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.
    1,3-bis(2-chloroethyl)-1-nitrosourea is an orange-yellow solid. (NTP, 1992)|Solid
    1,3-bis(2-chloroethyl)-1-nitrosourea is an orange-yellow solid. (NTP, 1992)|Carmustine is a member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group. It has a role as an alkylating agent and an antineoplastic agent. It is a member of N-nitrosoureas and an organochlorine compound.|A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (From Merck Index, 11th ed)|Carmustine is an Alkylating Drug. The mechanism of action of carmustine is as an Alkylating Activity.|Carmustine (BCNU) is a parenterally administered alkylating agent used alone and in combination with other antineoplastic agents in the treatment of several forms of cancer including leukemias, lymphomas, and breast, testicular, ovarian, gastric and pancreatic cancer. Carmustine therapy is associated with minor transient serum enzyme elevations and has been linked to cases of acute liver injury including cholestatic hepatitis and acute veno-occlusive disease.|Carmustine is an antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily. (NCI04)

    Certificates

    Basic Info
    Product Name:

    Carmustine

    Other Name:

    Urea,N,N′-bis(2-chloroethyl)-N-nitroso-;Urea,1,3-bis(2-chloroethyl)-1-nitroso-;N,N′-Bis(2-chloroethyl)-N-nitrosourea;BCNU;1,3-Bis(2-chlorethyl)-1-nitrosourea;Carmustine;1,3-Bis(β-chloroethyl)-1-nitrosourea;NSC 409962;Carmustin;1,3-Bis(2-chloroethyl)-1-nitrosourea;BiCNU;Gliadel;Becenun;SK 27702;SRI 1720;Nitrumon;FDA 0345;Carmubris;DTI 015;Gliadel Wafer;1,3-Bis(2-chloroethyl)nitrosourea;Becenum;1159711-15-5;1191292-23-5

    CAS No.:

    154-93-8

    Molecular Formula:

    C5H9Cl2N3O2

    InChIKeys:

    InChIKey=DLGOEMSEDOSKAD-UHFFFAOYSA-N

    Molecular Weight:

    214.05

    Exact Mass:

    214.05

    EC Number:

    205-838-2

    UNII:

    U68WG3173Y

    NSC Number:

    758392|409962

    UN Number:

    2811

    DSSTox ID:

    DTXSID8022743

    NCI Thesaurus Code:

    C349

    Color/Form:

    Light yellow powder|Light yellow powder that melts to an oily liquid

    ATC Code:

    L01AD01|L - Antineoplastic and immunomodulating agents

    HScode:

    2924199090

    Characteristics
    PSA:

    61.8

    XLogP3:

    1.5

    Appearance:

    Oily liquid to amorphous solid

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    31 °C

    Boiling Point:

    404ºC

    Refractive Index:

    1.549

    Water Solubility:

    H2O: <0.1 g/100 mL at 18 ºC

    Storage Conditions:

    −20°C

    Vapor Pressure:

    2.9X10-4 mm Hg at 25 deg C (est)

    Toxicity:

    Oral-rat LD50: 20 mg/kg; Oral-Mouse LD50: 19 mg/kg

    Flammability characteristics:

    Combustion produces toxic nitrogen oxides, chloride fumes; poisoning: nausea, vomiting, decreased white blood cells and platelets, bone marrow damage

    Henrys Law Constant:

    Henry's Law constant = 4.8X10-11 atm-cu m/mol at 25 °C (est)

    Experimental Properties:

    Polifeprosan 20 with carmustine implant ... off-white to pale yellow wafer /Gliadel wafer/|Hydroxyl radical reaction rate constant = 3.6X10-12 cu cm/molecule-sec at 25 °C (est)

    Air and Water Reactions:

    Insoluble in water.

    Reactive Group:

    Amides and Imides

    Reactivity Profile:

    1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA decomposes rapidly in acid and in solutions above pH 7; most stable in petroleum ether or aqueous solution at pH 4. (NTP, 1992)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Carcinogenicity, Category 1B

    Reproductive toxicity, Category 1B

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H350 May cause cancer

    H360 May damage fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Carmustine powder must be refrigerated at 2 - 8 deg C. Both the powder and its solutions must be protected from light.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    vitamin

    Location:

    Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    25 days

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    Less than 5

    Year of Establishment:

    2023

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Taiwan, China

    Carmustine

    100 MG Nov 5, 2024
    India

    Carmustine

    5 G Jun 23, 2025
    Post an enquiry for this product
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