 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Sotorasib for Sale > Sotorasib, AMG 510 2296729-00-3

Sotorasib, AMG 510 2296729-00-3

Name: Sotorasib, AMG 510 2296729-00-3
Brand: Zentrachem
SKU: pr2509181602
Price: 0.1 USD
Availability: InStock

ISO COA 2 Inquiries

Unit Price: Get Latest Price 

CAS No.:

2296729-00-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Zentrachem

Packaging:

25kgs in drum

Sample Available:

Yes

Price valid (until):

2025-11-30

Contact Supplier

 Chat Now

Hangzhou Zentra Bio-Chemical Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,100% TT in advance

Average Lead Time:

14 days

Qualification:

Main Products:

pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

samples available

we are capable of:

1) quick quotation, normally within 1-2 days

2) full marketing research

3) price control and quality(regulatory) control

4) all stage support from sample, pilot, registration and commercial

5) sourcing for prodcut which is very new or hard to find

6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing

What are the MOQ and lead time?

MOQ varies (high-value chemicals may negotiate to g-kg-level).

Lead time typically 2-4 weeks, with expedited options upon request.

How do we ensure product quality and compliance?

We enforce a 3-step protocol:

① Source only from ISO-certified suppliers;

② Provide batch-specific COA/COO;

③ Dedicated team monitors global regulations (e.g., China NECIC, EU SCIP).

Do we offer customized synthesis?

Yes!

We provide end-to-end solutions from R&D to scale-up production.

Technical specs (e.g., purity, CAS#) and intended use documentation are required.

How do we handle logistics and customs?

We support CIF/FOB/DDP/DAP terms, partner with global logistics providers,

and have in-house experts for HS code classification, hazardous material documentation, etc.

How do we manage raw material price fluctuations?

We mitigate risks via long-term contracts, multi-region sourcing,

and futures hedging, supplemented with quarterly market analysis reports.

Items Specifications

ECHEMI Editorial Reference

Sotorasib (AMG510) is a chiral compound and a potent KRAS G12C covalent inhibitor with potential antitumor activity.
ChEBI:Sotorasib is a pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRAS(G12C) mutations. It has a role as an antineoplastic agent. It is a member of acrylamides, a N-acylpiperazine, a pyridopyrimidine, a member of monofluorobenzenes, a member of methylpyridines, a tertiary carboxamide, a tertiary amino compound and a member of phenols.
Sotorasib, also known as AMG-510, is an acrylamide derived KRAS inhibitor developed by Amgen. It is indicated in the treatment of adult patients with KRAS G12C mutant non small cell lung cancer. This mutation makes up >50% of all KRAS mutations. Mutant KRAS discovered in 1982 but was not considered a druggable target until the mid-2010s. It is the first experimental KRAS inhibitor. The drug [MRTX849] is also currently being developed and has the same target. Sotorasib was granted FDA approval on 28 May 2021.
Class: non-kinase; Treatment: KRAS(G12C) NSCLC; Other name: AMG 510; Elimination half-life: 5.5 h; Protein binding = 89%

Certificates
Basic Info

Product Name:
Sotorasib

Other Name:
PYRIDO[2,3-D]PYRIMIDIN-2(1H)-ONE, 6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-[4-METHYL-2-(1-METHYLETHYL;Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-, (1R)-;AMG-510(Sotorasib);6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one;Storasib;CID 137278711;Pyrido[2,3-d]pyrimidin-2(1H)-one, 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]-, (1R)- 6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(4-methyl-2-propan-2-ylpyridin-3-yl)-4-[(2S)-2-methyl-4-prop-2-enoylpiperazin-1-yl]pyrido[2,3-d]pyrimidin-2-one;Sotorasib

CAS No.:
2296729-00-3

Molecular Formula:
C30H30F2N6O3

InChIKeys:
NXQKSXLFSAEQCZ-UHFFFAOYSA-N

Molecular Weight:
560.6

Color/Form:
White to yellow

Categories:
Bulk Drug Intermediates

Characteristics

Density:
1.36±0.1 g/cm3(Predicted)

Boiling Point:
730.5±70.0 °C(Predicted)

Water Solubility:
Water : 33.33 mg/mL (59.46 mM; ultrasonic and adjust pH to 11 with NaOH)

PKA:
6.52±0.35(Predicted)

Critical Temperature & Pressure:
Store at -20°C, stored under nitrogen

See More Sotorasib Properties 
Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,excipients,plant extracts,food additives,CDMO,fine cheimcals

Location:
Rm 301, Bld 2, Taohuahu Neighborhood Center, Hangzhou, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,100% TT in advance

Average lead Time:
14 days

Total Employees:
5-10

Year of Establishment:
2025

Zentra Chemical, headquartered in Hangzhou, China, is aiming to be a global leader in chemical trading and integrated solutions.

Specializing in Pharmaceutical intermediates, Agrochemical intermediates, Fine chemicals, and Cosmetic ingredients, we deliver end-to-end services spanning sourcing, supply chain optimization, customized synthesis, cost management, and quality assurance.

Our mission is to empower clients worldwide with agile, sustainable, and value-driven partnerships in the ever-evolving chemical industry.

Why us

Supplier, distributor & marketer of chemicals with >20 yrs of experience, with Integrated sourcing solutions.

Wide product range , We can source any fine chemical you require, unlimited range, including intermediates and products for agrochemicals, cosmetics, APIs, nanotechnology, additives, flavors, fragrances, photography, plant extracts, electronics industries and more.

We can solve your sourcing problems through our own or third party manufacturing in the most transparent way.

We supply all stage support from sample, pilot, registration and commercial.

Through selected pre-qualified partners under exclusive arrangements, we offer Contract manufacturing and custom synthesis , Kilo to Multi-ton scale production.

Capability

with hundreds of local manufacturers(pre-qualified), we are capable of:

1) quick quotation, normally within 1-2 days;

2) full marketing research;

3) price control and quality(regulatory) control;

4) all stage support from sample, pilot, registration and commercial;

5) sourcing for prodcut which is very new or hard to find;

6) CMO/CDMO, from pilot-scale development to industrial-scale manufacturing.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Pakistan	Sotorasib	1 MT	Sep 9, 2026
Pakistan	Sotorasib	1 KG	Sep 24, 2026

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Sotorasib CAS 2296729-00-3 First-in-Class KRAS G12C Covalent Inhibitor for NSCLC Research kr	Reagent Grade/99	$100-130/G FOB	Jinan topfull chemical co.,ltd	Inquiry
2296729-00-3 \| ChemExpress	/		ChemExpress	Inquiry

Sotorasib, AMG 510 2296729-00-3

Product Description

Seller Information

Inquiry History

More Choices Find All Products for Sale 

Related Searches

More from this Seller

Items	Specifications