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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Retatrutide for Sale > Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2
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Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2

TDS 6609 Inquiries

Unit Price: Get Latest Price
CAS No.:

2381089-83-2

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

LY

Packaging:

5mg 10mg 20mg 30mg 50mg 60mg

Price valid (until):

2025-10-19

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Tirzepatide,Semaglutide,Retatrutide

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Sales Manager: Lili
    Whatsapp: +86 187 1291 7923
    Email:lili@lianyi-kj.cn


     Product Detail  

    What is Retatrutide ?

    Retatrutide is an innovative triple receptor agonist drug developed by Eli Lilly, used for the treatment of type 2 diabetes and obesity. It targets GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptor (GCGR), regulating blood sugar and metabolism through multiple mechanisms: enhancing insulin secretion, suppressing appetite, delaying gastric emptying, and promoting fat burning. Clinical trials have shown that Retatrutide may be superior to existing GLP-1/GIP dual-targeted drugs (such as tiraglutide) in terms of lowering blood sugar and weight loss. Currently, it is in the III phase of research and is expected to be another major breakthrough in the field of metabolic treatment.

    Shop Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2-Detailed Image 1 Shop Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2-Detailed Image 2 Shop Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2-Detailed Image 3 Shop Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2-Detailed Image 4


    Benefits

    1. Rapidly stimulate insulin secretion, precisely lower post-meal blood sugar
    (1) Quickly activate pancreatic beta cells, promote insulin release
        Rhetalutide promotes calcium ion influx by closing ATP-sensitive potassium channels in beta cells. Within 30 minutes, it rapidly releases stored insulin, precisely controlling the peak of post-meal blood sugar (peaks within 1-2 hours), and its short-term effect lasts for 4-6 hours to avoid the risk of hypoglycemia before the next meal.
    (2) Glucose-dependent regulation, reducing the risk of basal hypoglycemia
        Rhetalutide has glucose-dependent secretion-promoting properties - it strongly stimulates insulin secretion when there is high post-meal blood sugar, and its effect weakens automatically when fasting. Compared to traditional sulfonylureas, it significantly reduces the risk of basal hypoglycemia, especially suitable for the elderly and individuals with glucose sensitivity.

    2. Flexible adaptation to diet, improving patients' medication compliance
    (1) Take medication with meals, can skip medication if meals are missed, avoiding ineffective medication
        Rhetalutide adopts the "take medication with meals" mode - it is only taken 15 minutes before meals. If there is no meal, it skips the medication. This flexible administration method avoids the risk of hypoglycemia when there is no food intake and adapts to irregular dietary rhythms, significantly improving medication safety and compliance.
    (2) Dose can be adjusted as needed, matching different meal calorie contents
        Rhetalutide supports flexible dose adjustment (0.5-4mg per dose). The dosage can be adjusted dynamically based on the calorie content of each meal. The daily dose does not exceed 16mg, achieving precise control of post-meal blood sugar, especially suitable for individuals with irregular diets.


    Items Specifications

    Product name

    Retatrutide

    CAS number

    2381089-83-2

    Side Effect

    No

    Usag

    Inj

    Pharmaceutical Technology

    Custom Synthesis

    Efficacy

    Weight Loss & Slimming

    Purity

    > 99.5% by HPLC

    Shipping

    7-15days

    Storage

    Sealed Storage, Away From Moisture

    Clinical Trial

    Type 2 Diabetes|Obesity|Overweight

    Transport Package

    Vials

    Specification

    5mg 10mg 15mg 20mg 30mg 50/60mg

    Origin

    China

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    Packing & Transportation

    We have professional packaging and shipping services.

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    Shop Ratetrutide a new generation of weight loss tool Triple Hormone Receptor Agonist GLP-1 Purity 99% 5mg CAS:2381089-83-2-Detailed Image 10


     Company Profile   

    Our company is a leading manufacturer and global supplier of high-quality pharmaceutical and chemical peptide products. We specialize in the research, development, and production of a diverse range of peptide-based compounds that meet the rigorous demands of the international pharmaceutical and biotech industries.

    Our core commitment is to excellence and reliability. All our manufacturing processes are strictly conducted in facilities that comply with international Good Manufacturing Practice (GMP) standards. This ensures the utmost quality, purity, and consistency in every product we deliver, providing our clients with complete confidence for their critical applications.

    With a strong focus on the global market, we have successfully established a widespread distribution network. Our products are extensively exported to over [Number, e.g., 40] countries worldwide, serving key regions including Europe, the Americas, Southeast Asia, the Middle East, and Africa.

    Driven by innovation and a customer-centric approach, our company is dedicated to being your trusted partner for premium peptide solutions, supporting advancements in healthcare and technology across the globe.



    ECHEMI Editorial Reference
    Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR, and GLP-1R with EC50 values of 2.32, 0.191 and 0.794 nM, respectively. It is an important tool for obesity research.Retatrutide potently activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R.Retatrutide is a synthetic peptide with glucose-lowering effects. It is an antidiabetic agent against type 2 diabetes (T2D), stimulating insulin and suppressing glucagon secretion in a glucose-dependent manner.Retatrutide was also shown to delay gastric emptying, lower fasting and postprandial glucose concentration, decrease food intake and reduce body weight in patients with type 2 diabetes.

    Certificates

    Basic Info
    Product Name:

    Retatrutide

    Other Name:

    Retatrutide;GIPR/GLP-1R;LY3437943Retatrutide;Retalutide;Retatrutide (sodium salt);Retatrutide RT5;retatrutide 5mg;Retatratide

    CAS No.:

    2381089-83-2

    Molecular Formula:

    C221H342N46O68

    Molecular Weight:

    4731.33

    EC Number:

    200-001-8

    Color/Form:

    White lyophilized

    Categories:

    Other Chemical Drugs

    Characteristics
    Water Solubility:

    Soluble in water (5mg/ml).

    Storage Conditions:

    -20°C

    Critical Temperature & Pressure:

    -20°C

    Research
    Class:

    Triple agonist — GCGR, GIPR, GLP-1R

    Status:

    Investigational (Phase 3)

    Mechanism:

    Simultaneously activates glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Engineered from the native GIP backbone with amino acid substitutions to confer GCGR and GLP-1R activity.

    EC50 (Human GCGR):

    5.79 nM

    EC50 (Mouse GIPR):

    0.191 nM

    EC50 (Mouse GLP1R):

    0.794 nM

    EC50 (Mouse GCGR):

    2.32 nM

    EC50 (Human GLP1R):

    0.775 nM

    EC50 (Human GIPR):

    0.0643 nM

    Source:

    Jastreboff AM, et al. N Engl J Med. 2023;389(6):514-526.DOI

    Clinical Development:

    NCT04881760; NCT05882045; NCT06354660

    References
    ChEMBL:

    CHEMBL5095485

    DrugBank:

    DB18993

    KEGG DRUG:

    D12430

    PubChem:

    PubChem

    Disclaimer:

    Retatrutide is an investigational compound not yet approved by FDA or EMA. This listing is for industrial and laboratory research use only. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Tirzepatide,Semaglutide,Retatrutide

    Location:

    Room 2012, No. 6-143, Section 2, Shanghai Road, Guta District, Jinzhou City, Liaoning Province

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    2

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2024

    Hebei Lianyi Technology Co., Ltd.

    (Jinzhou Hongbai Technology Co., Ltd. Subsidiary branch company)is a leading manufacturer and global supplier of high-quality pharmaceutical and chemical peptide products. We specialize in the research, development, and production of a diverse range of peptide-based compounds that meet the rigorous demands of the international pharmaceutical and biotech industries.

    Our core commitment is to excellence and reliability. All our manufacturing processes are strictly conducted in facilities that comply with international Good Manufacturing Practice (GMP) standards. This ensures the utmost quality, purity, and consistency in every product we deliver, providing our clients with complete confidence for their critical applications.

    With a strong focus on the global market, we have successfully established a widespread distribution network. Our products are extensively exported to over 20 countries worldwide, serving key regions including Europe, the Americas, Southeast Asia, the Middle East, and Africa.

    Driven by innovation and a customer-centric approach, Jinzhou Hongbai Technology Co., Ltd. is dedicated to being your trusted partner for premium peptide solutions, supporting advancements in healthcare and technology across the globe.

  • Inquiry History
    6609 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Retatrutide 2381089-83-2

    3 MT Mar 28, 2026
    United Kingdom

    Retatrutide - 2381089-83-2

    1 G Feb 10, 2026
    United States

    Retatrutide CAS 2381089-83-2 10mg vial

    20 MT Mar 7, 2026
    United States

    Factory Retatrutide API 99% Purity CAS 2381089-83-2

    5 KG Nov 10, 2025
    United Kingdom

    Peptide powder Retatrutide 99% pure for Body building cas 2381089-83-2 Weight Loss Peptide with COA

    1 MT Mar 22, 2026
    United States

    2381089-83-2

    100 G Jul 14, 2026
    United States

    2381089-83-2

    100 G Feb 24, 2026
    United States

    2381089-83-2

    100 MT Dec 9, 2023
    United States

    Retatrutide 2381089-83-2

    200 MG May 16, 2026
    United Kingdom

    2381089-83-2 retatrutide

    300 MG Feb 13, 2026
    United States

    Retatrutide 2381089-83-2 wholesale

    500 MT Nov 3, 2023
    Poland

    CAS 2381089-83-2 (Custom Peptide)

    40 MT Apr 10, 2026
    Austria

    Peptide Retatruide CAS 2381089-83-2

    100 MT Apr 4, 2026
    United States

    Retatrutide CAS 2381089-83-2 99%

    10 PCS Feb 21, 2026
    Austria

    Retatrutide CAS 2381089-83-2 10mg vial

    20 PCS Feb 10, 2026
    United States

    Tirzepatide 99.9% Liquid 2381089-83-2 TeruiOP

    1 MT Sep 6, 2023
    United States

    Retatrutide/LY3437943/GIPR/GLP-1R 98% Powder 2381089-83-2 Senwayer

    1 G Sep 3, 2023
    United States

    GLP-1 / GIP Retatrutide cas 2381089-83-2

    1 MT Oct 16, 2024
    United States

    Retatrutide 99% High Quality CAS 2381089-83-2

    1 G Jan 23, 2026
    United States

    Injection Peptide Tirzepatide/Retatrutide/ Semaglutide Peptides CAS 2381089-83-2

    10  Oct 21, 2023
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