Dirithromycin RC01837
62013-04-1
Pharmaceutical Grade
99%
Royalchem
25kg/drum
2029-12-31
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceDirithromycin(LY 237216) is a macrolide glycopeptide antibiotic by binding to the 50S subunit of the 70S bacterial ribosome to inhibit the translocation of peptides.Target: AntibacterialDirithromycin is a new macrolide with a spectrum and degree of in vitro antimicrobial activity similar to that of erythromycin. Compared with erythromycin, dirithromycin has a long elimination half-life enabling once-daily administration, and it also achieves a greater cellular:extracellular concentrationBasic Info
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Product Name:
Dirithromycin
Other Name:4,16-Dioxa-14-azabicyclo[11.3.1]heptadecan-5-one,7-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-,(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-;Erythromycin,9-deoxo-11-deoxy-9,11-[imino[2-(2-methoxyethoxy)ethylidene]oxy]-,[9S(R)]-;4,16-Dioxa-14-azabicyclo[11.3.1]heptadecane,erythromycin deriv.;(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-7-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-3-ethyl-2,10-dihydroxy-15-[(2-methoxyethoxy)methyl]-2,6,8,10,12,17-hexamethyl-9-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one;Antibiotic AS-E 136;Dirithromycin;LY 237216;ASE 136;Dirythromycin;KT 237216;Dynabac;Valodin;Noriclan;Nortron;77045-98-8
CAS No.:62013-04-1
Molecular Formula:C42H78N2O14
InChIKeys:InChIKey=WLOHNSSYAXHWNR-DWIOZXRMSA-N
Molecular Weight:835.07
Exact Mass:835.07
EC Number:1308068-626-2
DSSTox ID:DTXSID7048956
ATC Code:J - Antiinfectives for systemic use
HScode:29419000
Categories:
Characteristics-
PSA:
196
XLogP3:1.6
Appearance:white to off-white solid
Density:1.2±0.1 g/cm3
Melting Point:186-189 °C (decomp)
Boiling Point:871.8°C at 760 mmHg
Flash Point:481.0±34.3 °C
Refractive Index:1.533
Water Solubility:Poor
Storage Conditions:2-8°C
Toxicity:LD50 in mice (g/kg): >1 s.c.; >1 orally (Maier)
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product