Nitrendipine 39562-70-4
1 Inquiries
39562-70-4
Food grade
99%
shenzhen
Flying
10g/1kg/ 10kg/ 25kg
2025-12-07
vitamin
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceNitrendipine is a calcium channel blocker with marked vasodilator action.Target: Calcium ChannelNitrendipine is a dihydropyridine calcium channel blocker. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine blocked Ca2+ currents very potently, with half-block by subnanomolar concentrations. The concentration dependence of block had the form expected for 1:1 binding, with an apparent dissociation constant (Kd) of 0.36 nM. In contrast, when cells we
Solid
Nitrendipine is a dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in the treatment of hypertension. It has a role as a calcium channel blocker, an antihypertensive agent, a vasodilator agent and a geroprotector. It is a C-nitro compound, a dihydropyridine, an ethyl ester, a diester, a member of dicarboxylic acids and O-substituted derivatives and a methyl ester.|Nitrendipine is a calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.|A calcium channel blocker with marked vasodilator action. It is an effective antihypertensive agent and differs from other calcium channel blockers in that it does not reduce glomerular filtration rate and is mildly natriuretic, rather than sodium retentive.Basic Info-
Product Name:
Nitrendipine
Other Name:3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,3-ethyl 5-methyl ester;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,ethyl methyl ester;BAY-e 5009;Nitrendipine;Bayotensin;Baypress;(±)-BAY E 5009;(±)-Nitrendipine;Nitrepin;Nitrendipin;Bylotensin;Deiten;Nidrel;Cardif;Baylotensin;86052-02-0;146904-08-7
CAS No.:39562-70-4
Molecular Formula:C18H20N2O6
InChIKeys:InChIKey=PVHUJELLJLJGLN-UHFFFAOYSA-N
Molecular Weight:360.36
Exact Mass:360.36
EC Number:254-513-1
NSC Number:758466
DSSTox ID:DTXSID0023373
ATC Code:C - Cardiovascular system
HScode:2933399090
Categories:
Characteristics-
PSA:
110
XLogP3:2.9
Appearance:yellow to green powder
Density:1.2±0.1 g/cm3
Melting Point:158 °C
Boiling Point:464.8°C at 760 mmHg
Flash Point:249.5±28.7 °C
Refractive Index:1.554
Water Solubility:soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.
Storage Conditions:Store at RT
Toxicity:LD50 in mice, rats (mg/kg): 39, 12.6 i.v.; 2540, >10000 orally (Hoffmann)
Collision Cross Section:182.2 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|181.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Dermal
Acute toxicity - Category 4, Inhalation
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H312 Harmful in contact with skin
H332 Harmful if inhaled
Precautionary statement(s) Prevention P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P317 Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
vitamin
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Location:
Room 2-502, Building 6, Luneng Tehran Garden Building, No.8 Changbin Road, Xiuying district, Haikou City, Hainan Province
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Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
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Average lead Time:
25
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Total Annual Revenue:
$2.5 million-$5 million
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Total Employees:
Less than 5
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Year of Establishment:
2023
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
United States
nitrendipine
10 MG Mar 10, 2026 Post an enquiry for this product
