Bicalutamide RC10573
3 Inquiries
90357-06-5
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBicalutamide is a non-steroidal androgen receptor inhibitor.
Solid
N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide is a member of the class of (trifluoromethyl)benzenes that is 4-amino-2-(trifluoromethyl)benzonitrile in which one of the amino hydrogens is substituted by a 3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanoyl group. It is a member of (trifluoromethyl)benzenes, a monocarboxylic acid amide, a member of monofluorobenzenes, a nitrile, a sulfone and a tertiary alcohol.|Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers. Bicalutamide binds to the androgen receptor.|Bicalutamide is a nonsteroidal antiandrogen similar in structure to flutamide that is used widely in the therapy of prostate cancer and has been linked to rare instances of liver injury.Basic Info-
Product Name:
Bicalutamide
Other Name:Propanamide,N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-;Propanamide,N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,(±)-;N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide;ICI 176334;Casodex;(±)-4′-Cyano-α,α,α-trifluoro-3-[(p-fluorophenyl)sulfonyl]-2-methyl-m-lactotoluidide;Bicalutamide;Cosudex;ZD 176334;Casode;151262-58-7
CAS No.:90357-06-5
Molecular Formula:C18H14F4N2O4S
InChIKeys:InChIKey=LKJPYSCBVHEWIU-UHFFFAOYSA-N
Molecular Weight:430.37
Exact Mass:430.37
EC Number:618-534-3
NSC Number:759816|722665
DSSTox ID:DTXSID2022678
Color/Form:Crystals from 1:1 (v/v) mix of ethyl acetate and petroleum ether|Fine white to off-white powder
ATC Code:L02BB03|L - Antineoplastic and immunomodulating agents
HScode:29242995
Categories:
Characteristics-
PSA:
116
XLogP3:2.3
Appearance:Solid
Density:1.5±0.1 g/cm3
Melting Point:190-195 °C (decomp)
Boiling Point:650.3°C at 760 mmHg
Flash Point:347.1±31.5 °C
Refractive Index:1.578
Water Solubility:DMSO: >5mg/mL
Storage Conditions:Store at RT
Vapor Pressure:7.54X10-15 mm Hg at 25 deg C (est)
PKA:12None
Henrys Law Constant:Henry's Law constant = 2.82X10-15 atm-cu m/mol at 25 °C (est)
Dissociation Constants:12.0|pKa = 12.6 (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 2.99X10-11 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Vietnam
Bicalutamide
1 KG Feb 29, 2024 
United Kingdom
Bicalutamide
1 KG Nov 26, 2023 
Spain
Bicalutamide Powder Raw Material 99% Powder CAS 90357-06-5 EGC-Bicalutamide Powder Raw Material
5 G Jun 13, 2024 Post an enquiry for this product
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