Product Name: Diphenylphosphinic Chloride
CAS No.: 1499-21-4
Molecular Formula: C₁₂H₁₀ClOP
Purity: ≥97%
Appearance: White to off-white crystalline powder

Product Overview

Diphenylphosphinic Chloride (CAS 1499-21-4) is a highly versatile and reactive organophosphorus compound. It serves as a critical building block in organic synthesis, particularly valued in pharmaceutical R&D and advanced material science. Its unique structure, featuring a phosphorus center bonded to two phenyl groups and a highly reactive acid chloride group, makes it an ideal precursor for synthesizing a wide range of derivatives.

Key Features & Advantages:

• High Purity & Quality: We guarantee a consistent purity of ≥97%, ensuring reliable performance and high yields in your synthetic applications.

• Versatile Synthetic Intermediate: The reactive P-Cl bond allows for facile nucleophilic substitution, enabling the introduction of the diphenylphosphinyl moiety into target molecules.

• Critical for Ligand Synthesis: An essential precursor for creating sophisticated phosphine ligands, which are crucial in metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck reactions).

• Peptide Coupling Agent: Effectively used as a coupling reagent in the synthesis of peptides and amides.

• Strict Quality Control: Every batch is rigorously tested and accompanied by comprehensive analytical data (including NMR and HPLC) to meet the stringent requirements of our clients.

Primary Applications:

• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs). Scientific literature indicates its use in synthesizing potential drug candidates, such as Kv1.5 potassium channel inhibitors for the treatment of atrial fibrillation.

• Catalyst & Ligand Synthesis: A key starting material for the preparation of bidentate phosphine ligands, which are indispensable in homogeneous catalysis.

• Agrochemicals & Material Science: Used in the synthesis of molecules for agrochemicals (herbicides, pesticides) and advanced materials (e.g., flame retardants, photopolymerization initiators).

• Organic Synthesis: A valuable reagent for constructing P-C, P-N, and P-O bonds to create novel organophosphorus compounds.

Packaging & Storage:

• Packaging: Available from grams to multi-kilogram quantities. Custom packaging options are available to suit your needs.

• Storage: Handle with care. Must be stored under an inert atmosphere (e.g., N₂) in a cool, dry, and well-ventilated place. Moisture-sensitive and corrosive.

Why Choose Our Product?

We specialize in providing high-value chemical intermediates for research and industrial applications. We are committed to delivering not only superior product quality but also exceptional technical support. Our competitive pricing and reliable supply chain make us your ideal partner for both R&D and scale-up projects.

Contact us today to request a quotation, a sample, or a detailed technical data sheet!

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