Norethisterone Acetate RC07909
51-98-9
Pharmaceutical Grade
99%
Royalchem
25kg/drum
Yes
2030-01-01
Pharmaceutical intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceNorethindrone acetate is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
Norethisterone acetate is a 3-oxo Delta(4)-steroid that is norethisterone in which the hydroxy group has been converted to its acetate ester. It has a role as a synthetic oral contraceptive and a progestin. It is a 3-oxo-Delta(4) steroid, a terminal acetylenic compound and an acetate ester. It derives from a norethisterone.|Norethindrone Acetate is the orally bioavailable acetate salt of norethindrone, a synthetic progestin with some anabolic, estrogenic, and androgenic activities. As do all progestins, norethindrone binds to and activates nuclear progesterone receptors (PRs) in target tissues such as the pituitary and reproductive system; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes, followed by various transcriptional events and histone acetylation. Physiological effects include the inhibition of luteinizing hormone (LH) release, an increase in the endometrial luteal-phase, and alterations in endocervical mucus secretion.|Acetate ester of norethindrone that is used as a long-term contraceptive (CONTRACEPTIVE AGENTS).Basic Info-
Product Name:
Norethisterone acetate
Other Name:19-Norpregn-4-en-20-yn-3-one,17-(acetyloxy)-,(17α)-;19-Nor-17α-pregn-4-en-20-yn-3-one,17-hydroxy-,acetate;(17α)-17-(Acetyloxy)-19-norpregn-4-en-20-yn-3-one;17-Acetoxy-19-nor-17α-pregn-4-en-20-yn-3-one;17α-Ethinyl-19-nortestosterone acetate;17β-Hydroxy-19-nor-17α-pregn-4-en-20-yn-3-one acetate;Norethindrone acetate;Norethisteron acetate;Norethisterone acetate;Norethynyltestosterone acetate;Norethysterone acetate;Norlutate;Norlutin acetate;17α-Ethynyl-19-nortestosterone acetate;17α-Ethinyl-19-nortestosterone 17β-acetate;17α-Ethinyl-4-estrene-17β-ol-acetate-3-one;17β-Acetoxy-19-nor-17α-pregn-4-en-20-yn-3-one;19-Norethynyltestosterone acetate;Norethindrone 17-acetate;19-Norethisterone acetate;17β-Acetoxy-17α-ethinyl-4-estren-3-one;Norlutin A;Orlutate;Primolut-Nor;SH 420;Norethisterone 17-acetate;Milli-Anovlar;Progylut;Gynophase;Gynovlane;Miniphase;Aygestin;Milligynon;NSC 22844;Estalis
CAS No.:51-98-9
Molecular Formula:C22H28O3
InChIKeys:InChIKey=IMONTRJLAWHYGT-ZCPXKWAGSA-N
Molecular Weight:340.46
Exact Mass:340.46
EC Number:200-132-0
UNII:9S44LIC7OJ
NSC Number:22844
DSSTox ID:DTXSID4023381
NCI Thesaurus Code:C702
ATC Code:H01CC54
HScode:2915299090
Categories:
Characteristics-
PSA:
43.37000
XLogP3:3.99
Density:1.1±0.1 g/cm3
Melting Point:161.5 °C
Boiling Point:454.7±45.0 °C at 760 mmHg
Flash Point:197.1±28.8 °C
Refractive Index:1.556
Water Solubility:3.162mg/L(10 ºC)
Toxicity:dlt-mus-orl 1120 mg/kg/4W MUREAV 26,535,74
Collision Cross Section:186.3 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Carcinogenicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H351 Suspected of causing cancer
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Pharmaceutical intermediates
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Location:
Room 336, Building 7, No. 177 Xingqiao North Road, Xingqiao Street, Linping District, Hangzhou
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Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
14 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
Less than 5
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Year of Establishment:
2025
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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