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API Scopolamine

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CAS No.:

51-34-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-12-24

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    Scopolamine

    CAS number

    51-34-3

    Description

    Scopolamine is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Among the many uses are as an anesthetic premedication, in URINARY INCONTINENCE, in MOTION SICKNESS, as an antispasmodic, and as a mydriatic and cycloplegic.

    Related CAS #

    114-49-8 (HBr) 55-16-3 (HCl) 51-34-3 (free) 6533-68-2 (HBr trihydrate)

    Synonym

    Scopolamine; l-Scopolamine; Transderm SCOP; SEE; Hyoscine; (−)-Scopolamine; Isoptpo Hyoscine

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Scopolamine More Info

    Scopolamine is a naturally occurring tropane alkaloid derived from plants of the Solanaceae family, such as Datura stramonium and Scopolia carniolica. It is structurally similar to atropine and functions as a non-selective competitive antagonist of muscarinic acetylcholine receptors (M1–M5), exerting both central and peripheral anticholinergic effects .

    Mechanism of Action:

    Scopolamine works by blocking cholinergic transmission in the central nervous system, particularly by inhibiting signals from the vestibular nuclei to higher CNS centers and from the reticular formation to the vomiting center, which helps prevent motion-induced nausea and vomiting . It also reduces gastrointestinal motility and secretions, and causes sedation, pupillary dilation, and increased heart rate .

    Clinical Uses:

    Prevention of motion sickness via transdermal patch (e.g., Transderm Scop)

    Postoperative nausea and vomiting

    Premedication before anesthesia to reduce saliva and respiratory secretions

    Historically used for twilight sleep in obstetrics and to treat Parkinsonian tremors

    Side Effects:

    Common effects include drowsiness, dry mouth, blurred vision, and dizziness. At higher doses, it may cause hallucinations, delirium, or excitation .

    Pharmacokinetics:

    When applied via transdermal patch, scopolamine is absorbed slowly, reaching peak plasma levels in about 24 hours, with effects lasting up to 3 days. It crosses the blood-brain and placental barriers, and is metabolized extensively, with <10% excreted unchanged in urine.


    Shop API Scopolamine-Detailed Image 1

    Basic Info
    Product Name:

    (-)-Scopolamine

    Other Name:

    Benzeneacetic acid,α-(hydroxymethyl)-,(1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester,(αS)-;1αH,5αH-Tropan-3α-ol,6β,7β-epoxy-,(-)-tropate (ester);Benzeneacetic acid,α-(hydroxymethyl)-,9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester,[7(S)-(1α,2β,4β,5α,7β)]-;3-Oxa-9-azatricyclo[3.3.1.02,4]nonane,benzeneacetic acid deriv.;Scopolamine;Atrochin;Atroquin;(-)-Hyoscine;Hyoscine;9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol (-)-tropate;(-)-Scopolamine;Scopine (-)-tropate;6β,7β-Epoxy-3α-tropanyl S-(-)-tropate;6,7-Epoxytropine tropate;Scopine tropate;SEE;l-Scopolamine;Transderm-Scop;Scop;Scopoderm TTS;Tropic acid ester with scopine;Transcop;97991-84-9;14797-94-5;28901-63-5;58670-87-4;65319-33-7;226562-00-1

    CAS No.:

    51-34-3

    Molecular Formula:

    C17H21NO4

    InChIKeys:

    InChIKey=STECJAGHUSJQJN-FWXGHANASA-N

    Molecular Weight:

    303.35

    Exact Mass:

    303.35

    EC Number:

    200-090-3

    DSSTox ID:

    DTXSID6023573

    Color/Form:

    Viscous liquid

    ATC Code:

    A - Alimentary tract and metabolism|N - Nervous system|S - Sensory organs

    HScode:

    29399990

    Characteristics
    PSA:

    62.30000

    XLogP3:

    0.76

    Appearance:

    White crystalline powder

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    55 °C

    Boiling Point:

    460.3±45.0 °C at 760 mmHg

    Flash Point:

    232.2℃

    Refractive Index:

    1.614

    Water Solubility:

    95g/L(15 ºC)

    Storage Conditions:

    -20°C

    Vapor Pressure:

    7.18X10-9 mm Hg at 25 °C (est)

    Toxicity:

    Oral-Rat LD50 2650 mg/kg; Oral-Mouse LD50: 1275 mg/m3/4 hours

    Flammability characteristics:

    Combustible; Fire breaks down toxic nitrogen oxide fumes

    Specific rotation:

    D20 -28° (c = 2.7)

    Henrys Law Constant:

    Henry's Law constant = 3.36X10-16 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pKa = 7.75

    Experimental Properties:

    Crystals. Freely soluble in water, dilute alcohol; slightly soluble in absolute alcohol /Methyl nitrate/|Dihydrate: chisel-shaped prisms from ethanol+water, mp 38-40 °C. Monohydrate: efflorescent crystals, mp 55-57 °C. Anhydrous: long prisms, mp 82-82 °C. Very slightly soluble in water; soluble in alcohol, chlorform, ether, oils /DL-form/|ODORLESS /SCOPOLAMINE HYDROBROMIDE USP/|COLORLESS OR WHITE CRYSTALS OR WHITE GRANULAR POWDER /SCOPOLAMINE HYDROBROMIDE NF/|Hydroxyl radical reaction rate constant = 5.97X10-11 cy cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Acute toxicity - Category 1, Dermal

    Acute toxicity - Category 2, Inhalation

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H310 Fatal in contact with skin

    H330 Fatal if inhaled

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P262 Do not get in eyes, on skin, or on clothing.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P284 [In case of inadequate ventilation] wear respiratory protection.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P316 Get emergency medical help immediately.

    P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P320 Specific treatment is urgent (see ... on this label).

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    85 Inquiries
    Country Product Purchase Quantity Date Posted
    Bangladesh

    Scopolamine CAS 51-34-3 99%

    1 KG Oct 30, 2023
    United States

    Scopolamine 99.9% Powder 51-34-3 DW

    50 MT Oct 19, 2023
    Bangladesh

    Factory price CAS 51-34-3 Scopolamine powder

    100 G Nov 6, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    01850035067 MT Oct 14, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    1 20' Fcl Jun 16, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    1 KG Oct 17, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    10 G Nov 4, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    10 G Oct 21, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    100 G Oct 12, 2023
    Bangladesh

    Safe Delivery Scopolamine 99% Solid CAS 51-34-3

    1 KG Oct 10, 2023
    France

    Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder

    1 G Nov 6, 2023
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    Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder

    1 G Oct 30, 2023
    Bangladesh

    Best price scopolamin 99% cas 51-34-3 pure scopolamine Hyoscine

    20 G Nov 9, 2023
    United States

    Scopolamine hot sale CAS 51-34-3 wholesale Scopolamine powder

    5 G Sep 22, 2023
    Bangladesh

    Scopolamine 99% white powder 51-34-3 99% White A Scopolamine 99%

    10 G Dec 30, 2024
    France

    China Factory Sell 99% Scopolamine powder/ pure Scopolamine / API Scopolamine 51-34-3

    10 G Oct 24, 2023
    Bangladesh

    Scopolamine

    100 KG Apr 22, 2025
    Bangladesh

    Scopolamine

    1 KG May 21, 2026
    Bangladesh

    Scopolamine powder

    10 G Sep 8, 2025
    France

    Scopolamine

    100 KG Jul 3, 2024
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