Epithalon 10mg Vials Epitalon CAS 307297-39-8 Peptides Supply

1.  Description

Chemical properties: Epitalon belongs to the linear tetrapeptide compound, with a molecular structure of H-Ala-Glu-Asp-Gly-OH and core functional groups of peptide bonds, carboxyl groups, and amino groups. The chemical properties are stable and not easily hydrolyzed in neutral to weakly acidic environments, avoiding the defect of easy degradation of long-chain peptides. High temperature (≤ 100 ℃) short-term treatment can still maintain structural integrity and has good compatibility with most bioactive ingredients.
      Physical properties: Epitalon is a white to off white crystalline powder at room temperature, odorless and tasteless, with excellent water solubility. It can quickly dissolve in aqueous systems such as pure water and physiological saline, as well as polar organic solvents such as methanol and ethanol. It is insoluble in non-polar solvents such as ether and petroleum ether. It needs to be stored under dry, sealed, and dark conditions (2-8 ℃), and the purity of research grade and application grade products is usually ≥ 98%.
      Source and Preparation: Epitalon does not exist in a natural form and is prepared entirely through solid-phase or liquid-phase synthesis methods. Using high-purity amino acids as raw materials, the target peptide chain is constructed through multiple reactions such as condensation, deprotection, and purification. Finally, high-purity products are obtained through column chromatography, recrystallization, and other methods. The synthesis process requires precise control of reaction conditions to ensure the integrity and purity of the peptide chain structure.

2.  Application

       In the field of biomedical research, Epitalon is a core tool and reagent for studying aging mechanisms, used for regulating telomerase activity, investigating cellular aging signaling pathways, investigating the mechanisms of neurodegenerative diseases (such as Alzheimer's disease), and aging related diseases (such as cardiovascular disease). Analyze the effects of cell models (such as fibroblasts and neurons) and animal models on telomere length, cell proliferation, and aging markers, providing experimental evidence for the development of anti-aging drugs.
      In the field of high-end dietary supplements, Epitalon is used as an anti-aging functional ingredient to develop dietary supplements such as capsules and freeze-dried powders, targeting people who are concerned about aging management, immune enhancement, and physical function maintenance. Its small molecule structure is easily absorbed by the human body and can assist in regulating aging related metabolism in the body. It is suitable for long-term anti-aging and health preservation, postoperative recovery, and other scenarios, and must comply with relevant regional dietary supplement compliance standards.
        Anti aging skin care products: Epitalon is added to high-end anti-aging skin care products (such as essence liquid, face cream, freeze-dried powder) based on cell repair and anti-aging activity. It can penetrate the stratum corneum of the skin, act on fibroblasts in the dermis layer, promote collagen and elastin synthesis, improve aging problems such as skin sagging, fine lines, and dullness, adapt to the anti-aging needs of mature and young skin, and is gentle, non irritating, and highly compatible.

3. Main Efficacy

Telomere protection and cellular aging delay effect: The core mechanism is to activate the expression of telomerase reverse transcriptase (TERT), promoting the maintenance and elongation of telomere length. Telomeres are the "protective caps" at the ends of chromosomes, and their shortening is a key marker of cellular aging. Epitelons prolong telomeres, inhibit telomere wear, delay the entry of cells into the aging phase, and promote the repair and regeneration of aging cells, maintaining normal tissue function in the body.
      Antioxidant and cell protective effects: Epitalon can clear oxidative substances such as reactive oxygen species (ROS) and hydroxyl radicals in the body, reducing damage to cell membranes, DNA, and telomeres caused by oxidative stress; Simultaneously upregulate the expression of antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GSH Px), enhance the body's own antioxidant defense system, and reduce the impact of oxidative damage on cells.
       Immune regulation and function enhancement effects: Epitalon regulates the activity of immune cells (such as lymphocytes and macrophages), promotes the secretion of immune factors (IL-2, IFN - γ), and enhances the body's immune response to infection and injury; Simultaneously improving cellular energy metabolism, enhancing mitochondrial function, relieving fatigue, maintaining youthful bodily functions, and having potential protective effects on nervous, cardiovascular, and other systems.
      Skin anti-aging and repairing effects: Epitalon acts on skin fibroblasts, promoting the synthesis of collagen fibers and elastin, increasing the thickness of the dermis layer of the skin, and improving skin laxity and fine lines; Simultaneously repairing damaged skin barriers, reducing water loss, brightening skin tone, enhancing skin toughness and radiance, achieving a dual effect of deep anti-aging and repair.