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BEST CEFTIOFUR SODIUM ceftiofur sodium

Name: BEST CEFTIOFUR SODIUM ceftiofur sodium
Brand: JIU LONG
SKU: pr2511281546
Price: 102 USD
Availability: InStock

3 Inquiries

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CAS No.:

104010-37-9

Content:

90%

Port:

all chinese ports and airports

Brand:

JIU LONG

Packaging:

25kg/drum

Price valid (until):

2025-12-28

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Shandong Jiulong Veterinary APIs

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Tildipirosin,Tilmicosin Phosphate,Tilmicosin

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Ceftiofur Sodium is a third-generation cephalosporin antibiotic exclusively developed for veterinary use, with stronger water solubility and stability than its hydrochloride form. As a core veterinary antibacterial drug, it is widely used in the prevention and treatment of bacterial infections in livestock (swine, cattle, sheep) and poultry (chickens, ducks), especially for drug-resistant strains producing beta-lactamase.

Core Mechanism of Action: It exerts bactericidal effects by specifically binding to penicillin-binding proteins (PBPs) on the bacterial cell membrane, inhibiting the synthesis and cross-linking of bacterial cell wall peptidoglycan. This leads to the loss of bacterial cell wall integrity, osmotic pressure imbalance, and eventual bacterial lysis. Its key advantage is strong resistance to bacterial beta-lactamases (enzymes that inactivate antibiotics), making it effective against most drug-resistant Gram-negative and Gram-positive pathogens. The main antibacterial spectrum includes:

Gram-negative bacteria: Haemophilus parasuis (swine Glässer's disease), Pasteurella multocida (swine/bovine pasteurellosis), Escherichia coli (swine colibacillosis, poultry colibacillosis), Actinobacillus pleuropneumoniae (swine pleuropneumonia);
Gram-positive bacteria: Streptococcus suis (swine streptococcosis), Staphylococcus aureus (bovine mastitis, swine skin abscesses);
Other pathogens: Salmonella spp. (poultry pullorum disease, swine salmonellosis), Riemerella anatipestifer (duck serositis).

Main Application Scenarios:

Swine:
- Neonatal piglets (1-7 days old): Prevent and treat yellow/white diarrhea caused by E. coli via intramuscular injection (single administration, long-lasting protection);
- Weaned piglets: Control Glässer's disease (fever, joint swelling) and pleuropneumonia (cough, dyspnea) with water-soluble powders (mixed in drinking water) or injectables for severe cases;
- Sows: Treat postpartum metritis-mastitis-agalactia syndrome (MMA) via intramuscular injection, improving sow lactation and litter survival rate.
Cattle & Sheep:
- Dairy cows: Treat acute mastitis (caused by Staphylococcus aureus, Streptococcus agalactiae) via intramammary infusion or systemic injection, with no residue exceeding standards in milk (complies with EU MRLs);
- Beef cattle/sheep: Treat pasteurellosis (fever, nasal discharge) and foot rot (caused by Fusobacterium necrophorum) via intramuscular injection, reducing mortality.
Poultry (Chickens, Ducks):
- Broilers: Treat colibacillosis (air sacculitis, pericarditis) and salmonellosis (pullorum disease) via drinking water, reducing mortality by 30-50%;
- Layer hens: Prevent bacterial infections during peak egg production, avoiding egg drop caused by infections without affecting egg quality.

Product Advantages:

Excellent water solubility: Solubility ≥60g/100mL (25℃), higher than ceftiofur hydrochloride, making it easier to prepare high-concentration injectables or drinking water preparations, ensuring uniform drug intake for group animals;
Strong antibacterial & anti-resistance: Effective against beta-lactamase-producing strains, solving the problem of antibiotic resistance in intensive breeding;
Long-lasting efficacy: Elimination half-life is 10-14 hours in swine and 8-12 hours in cattle, requiring only 1 administration per day (injection or drinking water), reducing labor costs;
High safety: Low toxicity to target animals; no obvious irritation to injection sites (sterile grade); no teratogenic, mutagenic, or embryotoxic effects at recommended dosages; complies with international veterinary drug residue limits (EU MRLs, US FDA CVM standards);
Reliable quality:
- Ordinary grade: Produced in GMP workshops, with strict detection of purity, moisture, and related substances;
- Sterile grade: Manufactured in Class 100 sterile production areas, with 100% batch testing of sterility, bacterial endotoxins, and particulate matter; each batch is accompanied by a Certificate of Analysis (COA) for full quality traceability.

This product is a first-line antibacterial drug in global intensive livestock and poultry breeding industries, favored for its high efficacy and safety, and is an essential raw material for veterinary drug manufacturers to produce high-quality third-generation cephalosporin preparations.

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Basic Info

Product Name:

Ceftiofur sodium

Other Name:

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,sodium salt (1:1),(6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,monosodium salt,[6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(2-furanylcarbonyl)thio]methyl]-8-oxo-,monosodium salt,(6R,7R)-;Ceftiofur sodium;Naxcel;U 64279E;Ceftiofur sodium salt;sodium ceftiofur;Xceft;Excenell

CAS No.:

104010-37-9

Molecular Formula:

C19H17N5O7S3.Na

InChIKeys:

InChIKey=DJTLOEQCWGUKEM-JUODUXDSSA-N

Molecular Weight:

545.54

Exact Mass:

545.010925

EC Number:

1806241-263-5

HScode:

2941905990

Categories:

Veterinary Raw Materials

Characteristics

PSA:

259

XLogP3:

0.55630

Appearance:

Off-white Or Yellowish Crystalline Powder

Density:

1.81g/cm3

Water Solubility:

Freely soluble in aqueous solution

See More Ceftiofur sodium Properties 

Hazard Identification

Classification of the substance or mixture

Skin sensitization, Category 1

Respiratory sensitization, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H317 May cause an allergic skin reaction H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P284 [In case of inadequate ventilation] wear respiratory protection.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ceftiofur sodium Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Tildipirosin,Tilmicosin Phosphate,Tilmicosin

Location:
Yinfeng International Biopark, No.1177 Chunlan Road, High-tech district, Jinan City, Shandong Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
365

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
101-200

Year of Establishment:
2008

Certifications:
GMP

Company Profile

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Switzerland	Factory supply Ceftiofur sodium 99% White crystalline powder CAS 104010-37-9 for treatment of swine bacterial respiratory infection	10000 MT	Aug 28, 2023
Egypt	Ceftiofur Sodium	1000 KG	Apr 15, 2024
India	ceftifour sodium	130 KG	Dec 4, 2023

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