 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 3,5-Diamino-1,2,4-triazole for Sale > 1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2 buy - large image1

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2 buy - image1

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2 buy - image2

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2 buy - image3

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2 buy - image4

1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2

Name: 1H-1,2,4-Triazole-3,5-diamine CAS:1455-77-2
Brand: Orient
SKU: pr2511281651
Price: 5 USD
Availability: InStock

TDS 1 Inquiries

Unit Price: Get Latest Price 

CAS No.:

1455-77-2

Grade:

Industrial Grade

Content:

99%

Port:

SHANGHAI

Brand:

Orient

Packaging:

25kg/bag,500kg/bag, customized

Price valid (until):

2025-12-28

Contact Supplier

 Chat Now

Qingdao Orient Chemical Co.,LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

pharmaceutical intermediates,peptides,electronic chemicals

 Visit Store

Product Description
Seller Information
Inquiry History

Description

1H-1,2,4-Triazole-3,5-diamine Basic information

Product Name:	1H-1,2,4-Triazole-3,5-diamine
Synonyms:	3,5-DiaMino-1,2,4-triazole, 98% 25GR;3,5-Diamino-1H-1,2,4-triazole, Guanazole;1,2,4-triazolidine-3,5-diiMine;Guanazole SynonyMs 1H-1,2,4-Triazole-3,5-diaMine;(5-amino-2H-1,2,4-triazol-3-yl)amine;Guanazole (VAN) (8CI);4H-1,2,4-TRIAZOLE-3,5-DIAMINE;3-AMINO-1H-1,2,4-TRIAZOL-5-YLAMINE
CAS:	1455-77-2
MF:	C2H5N5
MW:	99.09
EINECS:	215-937-2
Product Categories:	Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks;Triazoles
Mol File:	1455-77-2.mol

1H-1,2,4-Triazole-3,5-diamine Chemical Properties

Melting point	202-205 °C (lit.)
Boiling point	473.7±28.0 °C(Predicted)
density	1.686±0.06 g/cm3(Predicted)
refractive index	1.7330 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,2-8°C
solubility	H₂O: clear to hazy
pka	12.10±0.40(Predicted)
form	powder
color	white
Water Solubility	Soluble in water.
BRN	112467
Stability:	Stability Air sensitive. Reacts with acids and oxidizing agents.
InChIKey	PKWIYNIDEDLDCJ-UHFFFAOYSA-N
CAS DataBase Reference	1455-77-2(CAS DataBase Reference)
NIST Chemistry Reference	3,5-Diamino-1,2,4-triazole(1455-77-2)
EPA Substance Registry System	Guanazole (1455-77-2)

Safety Information

Hazard Codes	Xn,Xi,C
Risk Statements	22-34
Safety Statements	36/37-45-36/37/39-27-26
WGK Germany	3
RTECS	XZ4535000
TSCA	Yes
HS Code	29339990

1H-1,2,4-Triazole-3,5-diamine Usage And Synthesis

Chemical Properties	colourless crystals or faintly yellow powder
Uses	3,5-Diamino-1,2,4-triazole is used as an inhibitor of DNA synthesis. It also serves as an antitumor agents in the treatment of epigenetically-based diseases. It acts as a corrosion inhibitor for copper.
Definition	ChEBI: An aromatic amine that is 1,2,4-triazole substituted at positions 3 and 5 by amino groups.
General Description	Colorless crystals.
Air & Water Reactions	1H-1,2,4-Triazole-3,5-diamine is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble.
Reactivity Profile	The triazoles, of which 1H-1,2,4-Triazole-3,5-diamine is a member, are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type of substitution to the triazole ring. The amine substituted derivatives, 1H-1,2,4-Triazole-3,5-diamine, tend not to be explosion sensitive. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. 1H-1,2,4-Triazole-3,5-diamine forms salts readily with acids.
Health Hazard	SYMPTOMS: 1H-1,2,4-Triazole-3,5-diamine is stable under normal laboratory conditions.
Fire Hazard	Flash point data for 1H-1,2,4-Triazole-3,5-diamine are not available. 1H-1,2,4-Triazole-3,5-diamine is probably combustible.
Safety Profile	Human systemic effects by intravenous route: leukopenia (reduced white blood cell count) and thrombo cytopenia (reduced blood platelet count). Human mutation data reported. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
Synthesis	127099-85-8 1455-77-2 1. 500 mL of water was added to a 2000 mL three-necked flask and 200.0 g of dicyandiamide was added with vigorous stirring for 20 minutes to form a turbid liquid. 2. 155 g of hydrazine sulfate was added to the cloudy liquid and the mixture was heated to 50°C. 3. 72 mL of 80% water was added slowly. 3. 72 mL of 80% hydrazine hydrate was added slowly, followed by warming the reaction system to 120°C to 125°C, during which all solids gradually dissolved. 4. the reaction mixture was stirred continuously at 120°C to 125°C for 16 hours, during which time a small amount of solids precipitated out of solution. 5. Upon completion of the reaction, the heating was stopped and the reaction mixture was cooled to room temperature. 6. The pH of the reaction mixture was adjusted to 9 by adding 100 mL of 10% sodium carbonate solution. 7. The reaction mixture was transferred to a 2 L dispensing funnel and the organic phase was extracted with 500 mL of dichloromethane. 8. The organic phase was washed with water and dried with anhydrous sodium sulfate. 9. Dichloromethane was removed by evaporation to give a white solid product. 10. The white solid was dried in a hot air oven to give a final product of 169 g of 3,5-diamino-1,2,4-triazole in 72% yield based on dicyandiamide.
Purification Methods	The triazole crystallises from water or EtOH. [Beilstein 26 III/IV 1161.]

Shop 4,4'-Diphenylmethane diisocyanate 101-68-8-Detailed Image 1

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 2

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 3

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 4

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 5

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 6

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 7

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 8

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 9

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 10

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 11

Shop Trimellitic Anhydride C9H4O5 552-30-7-Detailed Image 12

—— Q&A ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.

Certificates

Basic Info

Product Name:

3,5-Diamino-1,2,4-triazole

Other Name:

1H-1,2,4-Triazole-3,5-diamine;Guanazole;3,5-Diamino-1,2,4-triazole;3,5-Diamino-s-triazole;NSC 1895;3,5-Diamino-1H-1,2,4-triazole;NSC 166592;NSC 167391;NSC 167392;503-88-8

CAS No.:

1455-77-2

Molecular Formula:

C2H5N5

InChIKeys:

InChIKey=PKWIYNIDEDLDCJ-UHFFFAOYSA-N

Molecular Weight:

99.09

Exact Mass:

99.09

EC Number:

215-937-2

UNII:

I01TWM5267

NSC Number:

1895

DSSTox ID:

DTXSID0025367

NCI Thesaurus Code:

C531

HScode:

29339990

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

93.6

XLogP3:

-0.7

Appearance:

Guanazole appears as colorless crystals. (NTP, 1992)

Density:

1.686±0.06 g/cm3(Predicted)

Melting Point:

205 °C (decomp)

Boiling Point:

473.7±28.0 °C(Predicted)

Flash Point:

271.6±11.2 °C

Refractive Index:

1.7330 (estimate)

Water Solubility:

H2O: clear to hazy ;soluble in water.1H-1,2,4-Triazole-3,5-diamine is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble .

Storage Conditions:

Store in a cool, dry place. Keep container closed when not in use.

Vapor Pressure:

3.85E-09mmHg at 25°C

Air and Water Reactions:

This compound is sensitive to air. Dust can be explosive when suspended in air at specific concentrations. Water soluble.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Alerts:

Explosive

Reactivity Profile:

The triazoles, of which GUANAZOLE is a member, are a group of highly explosive materials that are sensitive to heat, friction, and impact. Sensitivity varies with the type of substitution to the triazole ring. The amine substituted derivatives, guanazole, tend not to be explosion sensitive. Metal chelated and halogen substitution of the triazol ring make for a particularly heat sensitive material. Azido and nitro derivatives have been employed as high explosives. No matter the derivative these materials should be treated as explosives. GUANAZOLE forms salts readily with acids. (NTP, 1992)

See More 3,5-Diamino-1,2,4-triazole Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled H315 Causes skin irritation H319 Causes serious eye irritation
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 3,5-Diamino-1,2,4-triazole Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
pharmaceutical intermediates,peptides,electronic chemicals

Location:
Room 102, 1st Floor, East Office Building, No. 45 Pengwan Road, Qianwan Bonded Port Area, Qingdao Zone, China (Shandong) Pilot Free Trade Zone

Payment Terms:
100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$10 million-$25 million

Total Employees:
51-100

Year of Establishment:
2024

A reliable supplier is like insurance.

We are mainly specilized in supply of pharmaceutical intermediates, electronic chemicals，food additives, and other fine chemical products.
Integrity is the foundation, quality is life. We would like to work together with you to build a greener and brighter future.

Website: orientchem.cc
Email: scarlett@orientchem.cc
WhatsApp: +86 17753254221

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
Italy	Guanazole 3,5-Diamino-1,2,4-Triazole	100 KG	Jan 9, 2025

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
China Most Professional Factory Supply High Qulity 3,5-Diamino-1,2,4-triazole;Guanazole CAS 1455-77-2	Pharmaceutical Grade/99		LEADER BIOCHEMICAL GROUP	Inquiry
Guanazole 3,5-Diamino-1,2,4-Triazole(1455-77-2)	/99	$15-16/KG FOB	LUYUNJIA CHEMISTRY XIAMEN LIMITED	Inquiry
1H-1,2,4-Triazole-3,5-diamine 1455-77-2	/		Shandong zhishang chemical Co.,Ltd	Inquiry
Guanazole 3,5-Diamino-1,2,4-Triazole cas 1455-77-2	/		SHANDONG LOOK CHEMICAL CO.,LTD	Inquiry
Guanazole	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry